Threadworms

Two drugs, both available without prescription - mebendazole and piperazine - are 

The fingernails can harbour eggs wash hands thoroughly and scrub under fingernails after using the toilet and keep fingernails short. Do not share towels. Wash all crockery, cutlery and cooking utensils carefully. 

A customer comes in to buy treatment for threadworm for the third time in 6 months. She says that her 6-year-old son keeps on getting infected even though she is taking scrupulous hygiene precautions. She has no idea how he keeps on catching it. What advice would you give  

Which of the following statements regarding treatment of threadworm infection with mebendazole is correct  

Questions on some topics have been poorly answered in the registration examination. These are usually highlighted in the Royal Pharmaceutical Society pre-registration bulletins and it may be useful to give these issues extra attention when revising. 

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The hexahydrate fonns colourless crystals, m.p. 44 C (104 C when anhydrous), b.p. 126 C. Made by the action of alcoholic ammonia on 1,2-dichloroethane, piperazine is used in human and veterinary medicine in the treatment of threadworm and roundworm infestations. 

Many parasitic worms cause systemic infections outside the gastrointestinal tract. These include Strong loides stercoralis (threadworm), Trichinella spiralis Dracunculus medinensis and the several species of nematodes that cause filariasis (Mansonellaperstans and Onchocerca volvulus). 

The exact mechanism of action of thiabendazole (Mintezol) is unknown. This drug appears to suppress egg or larval production and tiierefore may interrupt die life cycle of the helminth. Thiabendazole is used to treat threadworm. Thiabendazole may cause hypersensitivity reactions, drowsiness, and dizziness. 

Threadworm infections are caused by Enterobius vermicularis. The infestation starts when the patient ingests the worm s ova, which then hatch and infect the small intestine. The female threadworms migrate to the caecum and anus so that at night they lay their eggs in the perianal area. The eggs produce a sticky... 

Vermox is the proprietary preparation of mebendazole, which is an anthelmintic. A single dose of mebendazole is indicated in the management of threadworms, with a second dose 2-3 weeks later avoiding re-infection, which tends to be common. 

Staphylococcus aureus, Haemophilus influenzae, Streptococcus pyogenes and Pseudomonas aeruginosa are all microorganisms that can cause otitis media. Enterobius vermicularis is a threadworm leading to an infection characterised by itchy anus and the presence of white worms. 

Vermox is a proprietary preparation of mebendazole, an anthelmintic drug indicated for threadworm or ringworm infections. Mebendazole is administered as a single dose. A second dose can be administered 2-3 weeks after the first dose to prevent re-infection. All members of the family must be treated if the infection is detected in one family member. Use of mebendazole in children under 2 years is not recommended. 

Mebendazole is a benzimidazole carbamate derivative that is used for the treatment of threadworm, roundworm, whipworm and hookworm infections. It is not recommended for women who are pregnant and in children under 2 years because the manufacturer reports that toxicity in animal studies has been reported. 

Strongyloides stercoralis (threadworm) Ivermectin Albendazole or thiabendazole... 

N.A. Abutilon indicum (L.) Sweet Mucilage, tannins, asparagine." For bronchitis, skin conditions such as boils and ulcers, threadworms. 

Mebendazole is a broad-spectrum anthelmintic drug producing high cure rates in infestations by Ascaris, threadworms, hookworms, and whipworms. The drug is practically insoluble in water and... 

Elecampane is stated to possess expectorant, antitussive, diaphoretic, and bactericidal properties. Traditionally, it is used in the treatment of bronchial and tracheal catarrh, cough associated with pulmonary tuberculosis, and dry irritating cough in children. Alantolactone is used as an anthelmintic in the treatment of roundworm, threadworm, and whipworm infection. 

Tansy has anthelmintic, carminative, and antispasmodic properties and is known to act as a stimulant to abdominal viscera. Traditionally, it has been used for nematode infestation, topically for scabies (as a decoction) and pruritus ani (as an ointment), and specifically for roundworm or threadworm infestation in children. 

Thiabendazole has broad-.spectmm anthelmintic activity. It is used to (real enterobiasis, strongyloidiasis (threadworm infection), a.scariasis, uncinariasis (hookworm infection), and trichuriasis (whipworm infection). It has also been u.sed to relieve symptoms associated with cutaneous larva migrans (creeping eruption) and the inva.sive phase of trichinosis. In addition to its use in human medicine, thiabendazole is widely used in veterinary practice to control intestinal helminths in iive.stock. 

Nematoddes are pestiddes that kill parasitic worms such as roundworms or threadworms. Early ne-matocides were used as soil fumigants. Since the 1960s, a completely new group of nonfumigant ne-matocides has been developed. All are organophos-phorus or carbamate pesticides with marked (acute oral and dermal) toxicity to humans. 

The threadworm (Enterobius vermicularis) infests the human intestine. Reinfection and transfer to others are easily achieved by swallowing eggs. 

Mebendazole is the first-choice treatment for threadworm infection. 

Because the life cycle of the threadworm is about 30 days and some worms may be in the larval stage when the first dose is taken, the manufacturer recommends a second dose after 14 days to eliminate reinfection. 

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