Teratological

Environmental Resources Technology Environmental Teratology Information Center Database Eacihties Index System... 

Teratologic Evaluation of FDA 71-33, Stannous Chloride in Mice, PB 221,780, prepared by Pood Dmg Research Labs, for PDA, National Technical Information Service, Springfield, Va., Oct. 1972. 

Mn Inhalation Teratology Study in Rats with Cyclohexanone, a study performed by Bio/dynamics, Inc., East Millstone, N.J., for The Industrial Health Foundation, Aug. 1984. 

Teratology. Society (1994). FDA classification system of drugs for teratogenic risk. Teratology 49, 446- 47. 

Webster, W.S., Gemain, M.A., Edwards, M.J. (1985). The induction of microphthalmia, encephalo-cele, and other heat defects following hypothermia during the gastrulation process in the rat Teratology 31, 73-82. 

Ciba-Geigy Ltd (1983) Report on Irgastab T 265 (TK12152) teratology study in rats. Basel, Ciba-Geigy Ltd (Test No. 820465.2.1983). 

EPA 1978e. Teratology and acute toxicity of selected chemical pesticides administered by inhalation. Research Triangle Park, NC U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory. EPA-600/1-78-003 NTIS PB-277 077. 

FroschI. 1990. Prenatal toxicology of Wofatox 80 in rats. Teratology 42(2) 26A. 

Komeil AA, Abdalla MA, Younis HM, et al. 1988. Teratogenicity of three different insecticides in pregnant mice [Abstract]. Teratology 38 21 A. 

Kumar KBS, Devi KS. 1996. Methyl parathion induced teratological study in rats. J Environ Biol 17 51-57. 

FMC. 1980b. Final report Teratology study with FMC 5462 in rats. Conducted for Food Machinery and Chemical Corporation. Raltech Scientific Services, Madison, WI. Raltech study no. 79041. 

Colborn, T., Smolen, M.J., and Rolland, R. (1998). Environmental neurotoxic effects the search for new protocols in functional teratology. Toxicology and Industrial Health 14, 9-23. 

Meteyer, C.U., Loeffler, I.K., and Fallon, J.F. et al. (2000). Hind limb malformations in free-living northern leopard frogs Rana pipiens) from Maine, Minnesota, and Vermont suggest multiple etiologies. Teratology 62, 151-171. 

Ottinger, M.A., Abdelnabi, M., and Quiim, M. et al. (2002). Reproductive consequences of EDCs in birds—What do laboratory effects mean in field species Neurotoxicology and Teratology 24, 17-28. 

The initial concern for the possible hazard to humans exposed to 2,4,5-T was precipitated by teratologic studies conducted by Bionetics Research Institute under contract from The National Cancer Institute (2). In these studies, large doses of 2,4,5-T were administered to pregnant rats and mice for nine of the 21 days of pregnancy. The incidence of fetal abnormalities was slightly higher in the treated animals than in control animals. Later tests indicated that these abnormalities (cleft palate) may have been caused by 27 8 ppm of 2,3,7,8-tetrachloro-dibenzo-p-dioxin present as a contaminant in the 2,4,5-T sample used in the Bionetic study (3). After the results of the study were made known, the Panel on Herbicides of the President s Science Advisory Committee studied the total 2,4,5-T situation. The report of this committee was published in March, 1971 (4). 

Organization ofTeratology Information Services (www.otispregnancy.org) (Lists and links to teratology information services by locale many have telephone "warm-lines.")... 

Kelman BJ, Sikov MR. 1984. Transplacental movements of americium-241 in the guinea pig and early distribution kinetics in the dam. Teratology 29(2) 40A. 

Rommereim DN, Sikov MR. 1986. Relative embryotoxicity of 239Pu and241 Am in rats. Teratology 33(3) 93C-94C. 

Sikov MR, Rommereim DN. 1986. Evaluation of the embryotoxicity of uranium in rats. Teratology 33(3) 41C. 

IRDC. 1981. Teratology study in rats. International Research and Development Corporation. 

Monsanto. 1979. Summaries of mutagenicity studies, neurotoxicity studies, teratology studies, long term feeding studies, and 90-day inhalation studies on aryl phosphate ester products. 

Noda T, Mortia S, Ohgaki S. 1984. A Safety Evaluation of Chemicals Used in Household Products (V) Teratological Studies in 2-Ethylhexyl Diphenyl Phosphate in Rats. Annu Rep. Osaka City Inst. Public Health Environmental Science 46 82-88. 

---