Teratology Information Services

5 TERATOLOGY INFORMATION SERVICES 5.1 California Teratogen Registry 

The Dutch Teratology Information Center of The Netherlands is consulted by physicians, pharmacists, midwives, clinical geneticists, and veterinarians. Relevant patient data are stored in a computer. Whether a pregnancy is aborted or carried to term, information is kept on the conception products involved in each case (ref. 35). 

In Paris, the Centre de Renseignements sur les Agents Teratogenes supplies to medical professionals information on teratogenic risk when conception is 

ETIC is the most comprehensive of the on-line computer systems that provide access to the worldwide literature of teratology and reproductive toxicology. The ETIC file is continuously updated and improved to meet the changing needs of those responsible for testing, evaluating, and regulating substances to which humans are exposed. 

The focus of this chapter has been on information resources available primarily in the United States. There are, no doubt, resources in other countries that have not been covered. The authors welcome inquiries concerning the topics discussed in this paper. 

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Organization ofTeratology Information Services (www.otispregnancy.org) (Lists and links to teratology information services by locale many have telephone "warm-lines.")... 

McElhatton, P.R., Garbis, H.M., Elefant, E., Vial, T., Bellemin, B., Mastroiacovo, P., Arnon, J., Rodriguez-Pinilla, E., Schaefer, C., Pexieder, T, Merlob, P., and Dal Verme, S. (1996) The outcome of pregnancy in 689 women exposed to therapeutic doses of antidepressants. A collaborative study of the European Network of Teratology Information Services (ENTIS). Reprod Toxicol 10 285-294. 

OTIS Fact Sheets. Organization of Teratology Information Services. Available from < http //www.otispregnancy.org>. 

De Santis M, Di Gianantonio E, Cesari E, Ambrosini G, Straface G, Clementi M. First-trimester itraconazole exposure and pregnancy outcome a prospective cohort study of women contacting teratology information services in Italy. Drug Saf 2009 32 239-44. 

Teratologic Evaluation of FDA 71-33, Stannous Chloride in Mice, PB 221,780, prepared by Pood Dmg Research Labs, for PDA, National Technical Information Service, Springfield, Va., Oct. 1972. 

The Toxicology Information Services at the Karolinska Institutet 1n Stockholm, Sweden, publish a monthly bulletin entitled Teratology Lookout. This excellent source of references of interest to experimental teratologists and clinicians is compiled by an advisory panel. The secondary sources Biological Abstracts, Biological Abstracts/RRM, and Chemical Abstracts and the MEDLARS data bases are scanned by the use of computer profiles to spot pertinent material. Keywords have been added to each reference, and most references include author addresses. The contents are divided into seven... 

J. O Brien, S. Rosenwasser and M. Feingold, Teratogen Information Service preliminary analysis of data, Teratology, 33(3) (1986) 50C. 

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