Sudden infant death syndrome, and

Gates PN, Pridham JB, Webber JA. Sudden infant death syndrome and volatile antimony compounds. Lancet 1995 345(8946) 386-7. 

Sudden infant death syndrome and multiple immunizations... 

Studies report a great variation in liver zinc concentrations, maybe due to the different techniques used (Table 2). Kollmeier et al. (1992) studied the distribution of zinc in adult liver parenchyma from necropsy material, and found a small variation in intraorgan metal concentrations. They reported that zinc concentrations in the liver do not seem to be associated with sex or age (Kollmeier et al., 1992). Another study, conducted with children by Coni et al. (1996), confirmed these findings. They measured the concentration of metal in necropsy material from infants that died of sudden infant death syndrome and from pediatric control subjects, and found that a small liver sample is repaesentative of liver concentration in the whole liver. 

In the early 1980s there were concerns about the safety of whole cell pertussis vaccines in particular, it was claimed by some that the vaccine was associated with sudden infant death syndrome and encephalopathy [21 ]. Immunization rates fell, and many vaccines were withdrawn from the market. However, epidemiological studies have consistently failed to identify an association. It has been recently argued that such reactions may have occurred in metaboli-cally vulnerable children, specifically those with defects in fatty acid oxidation, in whom the combination of anorexia and fever due to the vaccine may have resulted... 

True. Nicotine, carbon monoxide and other harmful chemicals from the burning tobacco travel in the mother s bloodstream and can reach the foetus. This can result in impaired development and reduced birth weight. Tobacco smoke can also be harmful to young children and babies (sudden infant death syndrome). 

The diphtheria, pertussis, and tetanus (DPT) vaccine, which has prevented more than 95% morbidity from these diseases, has been linked with convulsions, encephalitis, and sudden infant death syndrome. ... 

Aim B, Milerad J, Wennergren G, Skjaerven R, Oyen N, Norvenius G, Daitveit AK, Helweg-Larsen K, Markestad T, Irgens LM. (1998). A case-control study of smoking and sudden infant death syndrome in the Scandinavian countries, 1992 to 1995. The Nordic Epidemiological SIDS Study. Arch Dis Child. 78(4) 329-34. 

Ford RP, Schluter PJ, Mitchell EA, Taylor BJ, Scragg R, Stewart AW. (1998). Fleavy caffeine intake in pregnancy and sudden infant death syndrome. New Zealand Cot Death Study Group. Arch Dis Child. 78(1) 9-13. 

Schellscheidt J, Oyen N, Jorch G. (1997). Interactions between maternal smoking and other prenatal risk factors for sudden infant death syndrome (SIDS). Acta Paediatr. 86(8) 857-63. 

Scottish frequency of the common G985 mutation in the medium-chain acyl-CoA dehydrogenase (MCAD) gene and the role of MCAD deficiency in sudden infant death syndrome (SIDS). 

In addition to all of the adverse effects and contraindications previously described for morphine, the following contraindications apply specifically to these drugs. They are contraindicated in pregnant women because of their potential teratogenic effects. They also can cause respiratory depression in the mother, which reduces oxygenation of fetal blood, and in the newborn the incidence of sudden infant death syndrome (SIDS) in the newborn is also increased. 

Sudden infant death syndrome. Water-soluble smoke extract, in cell culture supernatants of mouse fibroblasts (L-929 cell line), produced an increase in TNF-a from respiratory syncytial virus-infected cells. It decreased TNF-a from cells incubated with toxic shock syndrome toxin. Incubation with cigarette smoke extract decreased the NO production from respiratory syncytial virus-infected cells and increased the NO production from cells incubated with toxic shock syndrome toxin. Monocytes from a minority of individuals demonstrated extreme TNF-a responses and/or very high or very low NO. The proportion of samples in which extreme responses with a very high TNF-a and very low NO were detected was increased in the presence of the three agents to 20% compared with 0% observed with toxic shock syndrome toxin. One to 4% was observed with cigarette smoke extract or respiratory syncytial virus L Symphatomimetic activity. Water extract of the dried leaf, administered intravenously to cats at doses of 0.05 and 10-20 mg/kg. 

D. M. Weir, A. Busuttil, and C. Blackwell. Exposure to cigarette smoke, a major risk factor for sudden infant death syndrome effects of cigarette smoke on inflammatory responses to viral infection and bacterial toxins. FEMS Immunol Med Microbiol 1999 25(1-2) 145-154. 

Exposure to powerful drugs does have a serious impact on infant mortality, including low birth weight, developmental disabilities, and sudden infant death syndrome (SIDS). Use of crack cocaine has declined somewhat since the 1990s, but a 2001 study by the Journal of the American Medical Association concluded that much of the damage previously attributed to cocaine use may in fact be attributable to alcohol or tobacco that was also used by the mothers in question. Even moderate use of alcohol poses a risk to the fetus. 

Tester, D. J., Carturan, E., Dura, M., Reiken, S., Wronska, A., Marks, A. R., and Ackerman, M. J. (2006b). Molecular and Functional Characterization of Novel RyR2-Encoded Cardiac Ryanodine Receptor/Calcium Release Channel Mutations in Sudden Infant Death Syndrome. Heart Rhythm 3(5-Sl) S67. 

Sudden infant death syndrome (SIDS) is strongly linked to smoking in pregnant women and new mothers. Children of smoking mothers are more likely to have motor control problems, perception impairments, symptoms of hyperactivity, and conduct disorder in childhood. These children have a higher risk for cancer later in life. 

Mosko S, Richard C, McKenna J. Infant arousals during mother-infant bed sharing implications for infant sleep and sudden infant death syndrome research. Pediatrics 1997 100 841-849. 

Anderson HR Cook DG (1997) Passive smoking and sudden infant death syndrome Review of the epidemiological evidence. Thorax, 52 1003-1009. 

The hazards of cocaine specific for pregnant women include premature rupture of placental membranes, spontaneous abortion, abnormal labor, and several general medical risks (e.g., hypertension). Their babies typically have growth retardation with consequent lowered birthweight. Cocaine use is also related to sudden infant death syndrome, characterized by abnormal respiratory control, particularly during sleep. 

DPT shots kill at least two to four people a year, according to the Institute of Medicine study and perhaps as many as 900 a year- including a great number misclassified as victims of sudden infant death syndrome- according to the independent National Vaccine Information Center. James Cherry MD, a physician and professor of pediatrics at the University of California at Los Angeles is a widely recognized pertussis expert who has been a leader on advisory committees that help frame immunization policy for the American Academy of Pediatrics and the Centers for Disease Control. Back in 1979, at a symposium he said, All physicians are aware that pertussis vaccine occasionally produces severe reactions and that these may be associated with permanent sequellae [complications caused by the vaccine] or even death. ... 

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