Schedule 3 compound

The CWC addresses the destruction of the agents, which are defined under the CWC as Schedule 1 compounds, but it also addresses agent precursors, known as CWC Schedule 2 compounds. Schedule 2 compounds can be present in some types of agent treatment residues, such as RRS and EDS neutralent. These compounds are not considered hazardous constituents under the federal RCRA program however, some states have shown concern for some of these compounds in their regulatory programs. Like the chemical agents, there are no federal or state RCRA standards for their treatment. Further, applicability of the CWC to wastes that may contain low concentrations of Schedule 2 compounds... 

While most of the Schedule 1 compounds do not have commerical uses, nitrogen mustard (HN-2) has been used in chemotherapy, and both ricin and saxitoxin have demonstrated legitimate roles in medicine. Otherwise, there are no legitimate or even plausible uses for significant quantities of any Schedule... 

Security issues include the control of DEA scheduled compounds. For the less controlled substances, locked cages provide sufficient security however, the... 

Figure 2. Similarity of mass spectra of (a) scheduled compound chloropicrine and (b) nonscheduled compound carbon tetrachloride...

Method 3, however, poses an additional challenge to the participants if no reference standard is available because it implies that the participants must have the chemical synthesized. Laboratories that are capable of synthesizing CWC-related compounds, in general, show a high competence in the analysis of authentic/proficiency test samples. Commercially available Scheduled compounds, alcohols, and thioalcohols are listed in Annex 2. 

ANNEX 2. LIST OF COMMERCIALLY AVAILABLE SCHEDULED COMPOUNDS,... 

The analytical data (spectra) for each chemical available in the OCAD for each technique varies from single to multiple entries. It is quite common to find at least three MS spectra for particular widely known scheduled compounds. This has several advantages, for instance, if on-site data is requested, there is a range of choice of data to choose from. Spectra acquired from different instruments or conditions can be selected to suit the scenario of an inspection. As the database grows, however, analytical data determined to be redundant or of low quality maybe replaced. 

Applications of those rules are illustrated by examples for scheduled compounds and derivatives associated with the Scheduled compounds. 

Examples of names of Schedule compounds Schedule Name... 

Spectrometry of Chemical Weapons Convention Scheduled Compounds. 264... 

ELECTRON IMPACT MASS SPECTROMETRY OF CHEMICAL WEAPONS CONVENTION SCHEDULED COMPOUNDS... 

Determination of the intact CW agents in urine or blood may proceed by the methods commonly applied to water samples. Extraction with an organic solvent and subsequent cleanup with a Florisil column is a well-established procedure. Rather volatile, scheduled compounds can often be successfully recovered and purified from biological materials by means of dynamic headspace stripping and subsequent adsorption on Tenax tubes these tubes are then subjected to GC/MS analysis. 

For the GC/MS analysis of unknown chemicals, more or less universal procedures have to be used, because of the large variety in matrices and scheduled compounds. This requires the use of ROPs rather than of standard operating procedures (SOPs), because ROPs allow modification of procedures in the process of analysis (validation on the job). However, SOPs have to be followed for instrument calibration and validation. 

OPCW proficiency tests currently require the identification of between six and nine analytes (scheduled compounds or their degradation products) in matrices such as water, soil, and organic extracts. Identification must be confirmed by two independent techniques, and both identification and reporting must be in accordance with strict criteria. Although not mandatory, most laboratories rely on comparison with authentic compounds to confirm identification in order to minimize any chance of a false positive. If the authentic compound requires synthesis, then these tests are demanding in terms of time as well as in terms of detection and identification. 

These compounds vary in their specific mechanism of action and often have different effects on the individual patients. Thus, they are generally used in combinations, eg, corticosteroids with an alkylating agent, or an antimetaboUte with a plant alkaloid in a rotating schedule. 

Compounds available in the United States are Hsted in Table 1. Whereas they vary in degree, all of them share similar HabiUties of cardiovascular side effects, the potential for central nervous system (CNS) stimulation, the development of tolerance, and abuse potential. AH, with the exception of ma2indol, are derivatives of phenethylamine. The introduction of an oxygen atom on the -carbon of the side chain tends to reduce CNS stimulant properties without decreasing the anorectic activity. Following the Federal Controlled Dmg Act of 1970, dmgs were classified into one of five schedules according to medical utiUty and abuse potential. 

The University of Idaho and USFWS, with funds from the Bonneville Power Administration, are also gathering data for registration of erythromycin. Erythromycin is intended for control of bacterial kidney disease in salmonid fingerlings that can also be transmitted by broodstock to the eggs (9). If research is completed on schedule and data indicate that the compound is safe and effective, registration is scheduled for 1994 (see Antibiotics, MACROLIDES). 

Requirements for labelling of containers for supply may differ from those for conveyance. Key features of a supply label are to identify the substance (the chemical name in most cases) and any hazards and safety precuations. In Europe the classification, packaging and labelling of dangerous substances is covered by Directive 67/548/EEC as amended. This requires labels to identify appropriate risk and safety phrases (Tables 12.2 and 12.3) depending upon product properties. A substance is considered dangerous if in Part lA of an approved list or if it exhibits hazardous properties as defined in Schedule 1 for supply, or Schedule 2 for conveyance as shown in Tables 12.4 and 12.5. Substances not tested should be labelled Caution — substance not yet fully tested . Criteria for risk phrases are provided, e.g. as in Table 12.6 for toxic compounds. 

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