Who must report

Community Right to Know reporting (hazardous substances inventories) is required in New Jersey from selected employers. The identification of the employers who must report is based on their standard industrial classification (SIC) code. In the New Jersey Worker and Community Right to Know Act (N.J.S.A. 34 5A-1... 

The ability of a system to meet its requirements and specifications must be demonstrated and documented before it can be accepted and fielded as a military system. Performance tests of a military detector system typically are performed by the contractor (Contractor Tests) and by the government (Government Tests). The former often are witnessed by government personnel who independently report on the methodology and results. Contractor testing is conducted at contractor facilities and at government facilities (but... 

Section 8(e) is a reporting responsibility which went into effect January 1, 1977 (the date the law was effective). This requires any manufacturer, processor 0r distributor who learns of information which supports a conclusion that a substance or mixture presents a substantial risk, must report this to the Agency immediately. 

For most laboratories it is essential that their identity in a profieieney test is kept eonfidential, beeanse pnblic reports abont poor perfornianee eould ruin a laboratory. In the PT provider organization the identity of the laboratories should also be known only to a small number of persons, who must be regularly instraeted about their duty to keep this information eonfidential. The provider may be required to report the performance of the laboratories to an authority. In this case the participants have to agree upon this procedure prior to participation. 

Studies are conducted to evaluate the adverse effects of chemicals and drugs, and are usually based on an earlier study plan. Deviations from study plans are not common. However, such deviations cannot be anticipated or totally ignored. In such a situation, there is a need for documentary evidence. Whereas an amendment is a planned change to the study plan, a deviation is an unplanned change that occurs during the study. Study information, such as a deviation from the study plan, should be noted in documentation. Such notes may be initiated by other personnel involved in the study but should be acknowledged by the study director who must approve any corrective action taken. The study director should consider whether to consult with other scientists to determine the impact of any such information on the study and should report (and discuss where necessary) these deviations in the final report. 

The data are complex, but several major trends are apparent. First, there is an interaction between presentation order and question asked, such that the reverse order (in which the premise containing the lower pair of items is stated first) is easier than the forward order (stating the upper pair first) when the subject must report the top-most object (e.g., Who is... 

Much from the integrated summaries described above may be reused in this report, with the exception of the expert, who must personally sign the report. Expert reports contain the expert s curriculum vitae, and part of the regulatory review process is to evaluate whether the expert is actually qualified for this role. The choice of expert is important, and his/her independence is crucial because the role is that of a reviewer and not of a sponsor. Experts may nonetheless be drawn from within the sponsoring company with appropriate protections, although those from outside may carry more credibility in some jurisdictions. 

All research personnel must search for clues about safety events from many sources, such as information in clinical records at the study sites information in data collection forms (e.g. CRFs, diary cards, quality-of-life forms, psychiatric rating scales, etc.), occurrence of missed and/or unscheduled visits, dropouts and withdrawals use of any concomitant medications/devices and abnormal laboratory data. AEs may also occur simply as a result of study procedures and study participation. Information about definitions of AEs and requirements for reporting AEs must be clearly stated in the protocol and explained to the site staff, who must also be educated in the correct procedure and immediate requirement for reporting any AE suspected to be serious or unexpected as per the regulatory definitions. 

Staff must report findings such as presentation of false, misleading and fraudulent information provided to WHO. 

Compression characteristics are extremely important for bulk size reduction operations (Murthy and Battacharya, 1998), especially in military and domestic applications. Compressed powders can be used by armed forces for field rations, by astronauts during space travel, and by hikers and others who must carry their own food supplies. Powders can be compressed by mechanical presses with savings in transportation costs, storage space (Van Heyst, 1983), and packaging material. Webb and Hufnagel (1943) reported a 42% savings in space with compressed dry whole milk (Van Heyst, 1983). 

Alendronate is currently the drug of choice to prevent osteoporosis in patients who must be maintained on steroids for their antiinflammatory and immunosuppressive effects. The drug also decreases bone resorption during menopause and is sometimes favored in patients who are at risk for neoplasias if treated with sex hormones. Care must be taken with alendronate to avoid esophageal ulceration. Estrogen hormone replacement therapy +/- vitamin D also has proven value for slowing bone resorption in menopause, and increases in bone mass have been reported for combinations of estrogens with alendronate. 

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