Recognition molecules

SHARON N, LIS H (1989) Lectins as cell recognition molecules. Science. 246 227-34. 

I. P. Fraser, H. Koziel, and R. A. B. Ezekowitz, The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity, Semin. Immunol., 10 (1998) 363-372. 

Giese, K. P.,Martini, R., Lemke, G., Soriano, P. and Schachner, M. Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons. Cell 71 565-576,1992. 

The sensors in this section can also be utilized to detect chemicals in liquid through the bulk solution refractive index change induced by the presence of target chemicals. Since no recognition molecules are used, this type of chemical sensing may usually have low specificity. However, these sensors may perform excellently in conjunction with other technologies such as capillary electrophoresis, mass spectrometer, and liquid chromatography in chemical detection. 

Affinity liquid chromatography and chiral separations (enantiomer separations) require similar analyte properties. The solutes may have interactions through hydrogen-bonding, ligand formation, or Coulombic forces with the surface of stationary phase materials or the sites of additives however, the selectivity is controlled by the steric effects of the structures of the analyte molecules and the recognition molecules (chiral selectors). 

Lipoproteins are classified into five groups. In order of decreasing size and increasing density, these are chylomicrons, VLDLs (very-low-density lipoproteins), IDLs (inter-mediate-density lipoproteins), LDLs (low-density lipoproteins), and HDLs (high-density lipoproteins). The proportions of apoproteins range from 1 % in chylomicrons to over 50% in HDLs. These proteins serve less for solubility purposes, but rather function as recognition molecules for the membrane receptors and enzymes that are involved in lipid exchange. 

Schachner M (1997) Nemal recognition molecules and synaptic plasticity. Cmr Opin Cell Biol 9 627-634... 

Poon, I. K., Flulett, M. D., and Parish, C. R. (2010). Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via FcgammaRI on phagocytes. Blood 115, 2473-2482. 

Peles, E., Nativ, M., Campbell, P.L., Sakurai, T., Martinez, R., Lev, S., Clary, D.O., Schilling, I, Barnea, G. and Plowman, G.D. The carbonic acid anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin (1995) Cell 82, 251-260... 

Additional Cell Adhesion Proteins Are Required to Mediate the Immune Response Immune Recognition Molecules Are Evolutionarily Related... 

These recognition molecules can either repel or attract growing axons, sending directions for axonal travel like a semaphore signaling a navy ship (Fig. 1 — 19). Indeed, some of these molecules are called semaphorins to reflect this function. Once the axon growth tip reaches port, it is told to collapse by semaphorin molecules called collapsins, allowing the axon to dock into its appropriate postsynaptic slip... 

Stahl, S.M. (1998) Recognition molecules are trailblazers for axon pathways. Journal of Clinical Psychiatry 59(5), 215—6. 

The common microbial patterns render recognition by organisms and their self/ nonself recognition is based on innate mechanisms. The common microbial patterns include lipopolysaccharides (LPS), mannose, fucose, technoic acid and /V-formyl peptides. These common microbial patterns are called pattern recognition molecules (PRMs) or pattern recognition receptors (PRRs). 

Lu, J., the, C., Kishore, U., and Reid, K. B. M. (2002). Collectins and ficolins Sugar pattern recognition molecules of the mammalian innate immune system. Biochim. Biophys. Acta 1572, 387-400. 

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