Towards electrochemical recognition of neutral guest species by redox-active receptor molecules

4 Towards electrochemical recognition of neutral guest species by redox-active receptor molecules 

As part of an ongoing research programme aimed at the construction of redox-active calixarene-based host molecules designed to sense neutral 

Electrochemical studies of the behaviour of [100] (5 X 10 4 mol dm-3 in dichloromethane solution containing 0.1 mol dm-3 [NBu ]BF4 as supporting electrolyte) have been carried out using cyclic and square-wave voltammetric techniques. The receptor itself undergoes two quasi-reversible oxidations at Epi = +350 mV and Ep2 = +450 mV referenced to Ag/Ag+. Rotating disk 

Preliminary electrochemical investigations on the effects of addition of potential neutral guests (DMF, DMSO, ethanol) to a solution of [100] in CH2C12 show an interesting effect. For example Fig. 59 shows the CV of [100] in CH2C12 background solution upon addition of progressive amounts of DMF. 

Shinkai and co-workers (Ori and Shinkai, 1995) have recently extended their work using ferroceneboronic acid derivatives to the detection of neutral molecules. A chiral ferroceneboronic acid [101] bearing a tertiary amino group 

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