Recognition of neutral molecules

The binding and recognition of neutral molecules make use of electrostatic, donor-acceptor and especially of hydrogen bonding interactions [2.119-2.123]. Polar organic molecules such as malonodinitrile form weak complexes with crown ethers and related ligands [2.120]. 

S. E. Matthews and P. D. Beer, Calixarene-based Anion Receptors, in Reference lb, p. 421. A. Arduini, A. Pochini, A. Secchi and F. Ugozzoli, Recognition of Neutral Molecules,in Reference lb, p. 457. 

The chiral molecular recognition of neutral molecules has become an important subject in the fields of analytical, biochemical and pharmaceutical technologies. 

Arduini. A. Pochini, A. Secchi, A. Ugozzoli, F. Recognition of Neutral Molecules. In Calixarenes 2001 Asfari, Z.. Bohmer, V., Hanowfield, J.. Vicens. J.. Eds. Kluwer Academic Publisher Dordrecht, 2001 457-475. 

Canceill, J. Cesario. M. Collet A. Guilhem, J. Riche, C. Pascard. C. Selective recognition of neutral molecules H NMR study of the complexation of CH2CI2 and CH2Br2 by Cryptophane-D in solution and crystal-structure of its CH2CI2 cavitate. J. Chem. Soc., Chem. Commun. 1986. 339-341. 

Webb TH and WUcox CS (1993) Enantioselective and diastereoselective molecular recognition of neutral molecules. Chemical Society Reviews 22 383 395. Wenzel TJ (1987) NMR Shift Reagents. Boca Raton (FL) CRC Press. 

Webb TH, Wilcox CS. Enantioselective and diastereoselec-tive molecular recognition of neutral molecules. Chem. Soc. Rev. 1993 22(6) 383-395. 

Towards electrochemical recognition of neutral guest species by redox-active receptor molecules... 

IV. Electrochemical Recognition of Neutral Guest Species Redox-Active Cavitand Host Molecules... 

Not all separations can be accomplished with simple buffers. For example, chiral recognition and separation of neutral molecules always require additives. Even charged-molecule separations can often be improved via secondary equi-... 

In contrast to the recognition of cations or anions, the eiectrochemical sensing of neutral molecules by redox-active receptors is less common. A number of supramo-... 

One of the chief reasons for the recent extensive work in this field has been the recognition that ion-molecule reactions are highly relevant to radiation chemistry. The possibility that certain simple reactions, such as the formation of H3+, participate in the mechanism of product formation was appreciated much earlier 14), but wider applicability of this concept required that the generality of such reactions be demonstrated by an independent, unequivocal method. Mass spectrometry has been the predominant means of investigating ion-molecule reactions. The direct identification of reactant and product ions is appealing, at least in part, because of the conceptual simplicity of this approach. However, the neutral products of ion-molecule reactions cannot be determined directly and must be inferred. Gross chemical measurements can serve as an auxiliary technique since they allow identification of un-... 

Effective charge and transition-state structure in solution, 27, 1 Effective molarities of intramolecular reactions, 17,183 Electrical conduction in organic solids, 16,159 Electrochemical methods, study of reactive intermediates by, 19, 131 Electrochemical recognition of charged and neutral guest species by redox-active receptor molecules, 31, 1... 

Receptor molecules, redox-active, electrochemical recognition of charged and neutral guest species... 

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