Enantioseparation recognition molecule

CyDs offer several advantages as chiral selectors for CE. The most important is that these macrocydic molecules possess a quite universal chiral recognition ability for many different dasses of organic compounds. In addition, CyDs are water soluble, transparent in the UV range, relatively inexpensive, and nontoxic. All of these contribute significantly to the status of CyDs as one of the most useful chiral selectors in CE. Free hydroxyl groups on the outer rim of CyDs offers various derivatiza-tion possibilities for introduction of nonionic and ionic groups into the structure of CyDs. Several CyD derivatives developed to be used in enantioseparations are presented in Chapter 2. 

Owing to some unique properties, cyclodextrins have been successfidly established as very useful chiral selectors in all instrumental analytical enantioseparation techniques. Further studies are required for a better understanding of the fine mechanisms of enantioselective recognition of these wonderful macrocydic molecules as well as for evaluation of their potential for preparative scale enantioseparations. 

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