Recognition Molecules Are Evolutionarily Related

Antigen-specific reactions involving T cells, (a) Killer T cells interact and destroy target cells that display complexes of processed antigen with an MHC I protein. Effective interaction requires that the TCR [Pg.846]

In this supplement we considered the major findings that led to our understanding of the immune system in vertebrates, especially mice and humans. The following points are the highlights of our discussion. [Pg.846]

Two different classes of white cells (lymphocytes) are associated with the immune response The B cells and the T cells. B cells produce antibodies that are secreted and aggregated foreign substances known as antigens. T cells are of different types Some of them assist B cells to become antibody-forming cells others mount an attack on antigens of their own. [Pg.846]

According to some estimates, each organism is capable of making more than a million different antibodies from a limited amount of genetic information. This feat is accomplished with the help of somatic recom- [Pg.846]

Complement is a group of serum proteins that aids in the defense against microorganisms and removal of antibody-antigen complexes. [Pg.846]

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