Pomegranate seed oil

Schubert, S.Y., Lansky, E.P., and Neeman, I., Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids, J. Ethnopharmacol., 66, 11, 1999. 

Pomegranate seed oil administered orally or intramuscularly increased the uterine weight in ovariectomized mice and increased vaginal cornification in immature female rabbits (Sharaf 1969 Sharaf and Nigm 1964). 

A polyphenol-rich fraction of pomegranate seed oil inhibited 17p-hydroxysteroid dehydrogenase type 1 at concentrations ranging from 100 to 1000 pg/ml. The oil also inhibited proliferation of estrogen receptor (ER)-positive human breast cancer cells (MCF-7), inhibited invasion of MGF-7 across a membrane, and induced apoptosis in ER-negative human breast cancer cells (MDA-MB-435) (Kim et al. 2002). An older study indicated that dried pomegranate seed contains the compound estrone at a concentration of 17 mg/kg (Heftmann et al. 1966) a more recent analysis indicated that no estrone was present (Choi et al. 2006). 

Pomegranate seed oil was not toxic to brine shrimp larvae (Fatope et al. 2002). 

A lack of adverse effects was noted in rats administered a diet containing 0.01 to 1% pomegranate seed oil for up to 32 weeks (Kohno et al. 2004). 

Kohno, H., R. Suzuki, Y. Yasui, et al. 2004. Pomegranate seed oil rich in conjugated linolenic acid suppresses chemically induced colon carcinogenesis in rats. Cancer Sci. 95(6) 481-486. 

Abbreviations CLA, conjugated linoleic acid PGO, pomegranate seed oil BGO, bitter gourd seed oil CTO, catalpa seed oil PMO, pot marigold seed oil ND, not detected. 

Sharaf A, Nigm SAR. The oestrogenic acitvity of pomegranate seed oil. J Endocrinol 1964 29 91-92. 

The fruits of pomegranate (Punica granatum, L. Punicaceae) are popular in the East and far East countries. The dried pericarp has been utilized in folk medicine for colic, colitis, diarrhea, dysentery, leucorrhea, menorrhagia, oxyuriasis, paralysis and rectocele. The flavonoid extract from cold pressed seed oil showed 31-44% inhibition of sheep COX-1 enzyme and 69-81% inhibition of soybean lipoxygenase [181]. 

Pomegranate and Gac stand for pomegranate and gac seed oil, respectively. Numbers correspond to the references cited, nd stands for not detected. 

Preheat oven to 350°F. Place broccoli in a casserole dish, and pour canola oil, curry powder, and lemon juice evenly over florets. Cover and bake until tender, about 20 minutes. Mix mango chunks into broccoli. Spoon contents onto two salad plates, and sprinkle half of the pomegranate seeds evenly over each plate. Serve warm. 

V2 cup brown sugar 4 cup olive or canola oil 1 tablespoon ground ginger 1 tablespoon curry powder 1 cup unpeeled mango chunks 1 cup canned peach halves, drained 1 cup pineapple chunks, drained 1 cup black mission figs >2 cup pomegranate seeds >2 cup walnut pieces 1 cup fresh or frozen blackberries... 

The first phytooestrogen identified in plants was oestrone, found in small quantities in pahn and pahn kernel oils (obtained from oil pahn, Elaeis guineensis, Arecaceae) and pomegranate seeds Punica granatum, Punicaceae). 

Punica granatum (pomegranate) (Punicaceae) [seed], Malus domestica (Rosaceae) fruit vegetable oil animals Oestrone isolated by Edward Doisy (USA) (Nobel Prize, Medicine, 1943, with Henrik Dam, Vitamin K)... 

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