Lip Hydroxysteroid dehydrogenase type

Seckl,J.R.andWalker,B.R.Minireview liP-Hydroxysteroid dehydrogenase type 1 — A tissue-specific amplifier of glucocorticoid action. Endocrinology 142 1371-1376, 2001. [Pg.857]

Rollinger et al. used a previously experimentally validated pharmacophore model for lip-hydroxysteroid dehydrogenase type 1 (lip-HSDl) to screen the DIOS database [95]. On the basis of the reported plant constituents in the hit list, triterpenoids... [Pg.142]

Adie, J.E. (2010) Stmcture-based dmg design of lip-hydroxysteroid dehydrogenase type 1 inhibitors. PhD. thesis. University of Edinburgh. [Pg.166]

Banhegyi G, Benedetti A, Fulceri R, Senesi S (2004) Cooperativity between lip-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the lumen of the endoplasmic reticulum. J Biol Chem 279(26) 27017-27021... [Pg.3822]

Wamil M, Seckl JR (2007) Inhibition of lip-hydroxysteroid dehydrogenase type 1 as a promising therapeutic target. Drug Discov Today 12(13/14) 504—520... [Pg.3822]

Tanahashi T, Munea T, Morita H, Tanahashi H, Isomura Y, Suwa T, Daido H, Gomez-Sancehz CE, Yasuda K (2002) Glycyrrhizic acid suppresses type 2 lip-hydroxysteroid dehydrogenase expression in vivo. J Steroid Biochem Mol Biol 80 441-447... [Pg.3821]

Fig. 25 Mouse liver microsome (MLM) half-life data for piperidine-based 11 P-hydroxysteroid dehydrogenase type I (lip-HSDl) inhibitors...

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