Performance testing protocols

Forensic Serology. Blood, often associated with crimes of violence, is powerfiil physical evidence. Its presence suggests association with the criminal act and blood can be used to associate suspects and locations with the bleeder. Blood is a complex mixture of cellular material, proteins, and enzymes and several tests are available for suspected bloody evidence. A typical test protocol involves (/) determining whether blood is present, (2) determining if it is human blood, (J) typing the blood, and (4) when appHcable, performing DNA typing. 

Performance. Consumer acceptance is a criterion on which cosmetic marketers caimot compromise. Whereas the likes and dislikes of consumers are in a state of constant flux, some product features are critical. A deodorant that does not deodorize or a hair coloring that fades in sunlight is unacceptable. Performance is tested by in vitro techniques during formulation, but the ultimate test of a product s performance requires in-use experience with consumers and critical assessment by trained observers. Performance tests can sometimes be combined with in-use safety tests, and protocols for such programs have been developed. 

Flame arresters cannot be designed from first principles and can only be proven by tests simnlating the conditions of nse. The riser should ensure that a flame arrester has been properly tested to meet the intended purpose, and should be prepared to stipulate the required performance standard or test protocol to be followed. 

According to test protocols described above, RPA-FT test were performed at 100°C, 1 Hz on all samples additional tests at 100°C, 0.5 Hz were performed on IMA TR, IMA FM, and IMA-AG samples. Essentially three types of data will be discussed hereafter The complex modulus G (as derived from the main torque component in the FT torque spectrum), the corrected total torque harmonic component, i.e., cTTHC, and the Q1/Q2 ratio. 

Michael Story is retired from Thermo Electron Corporation. He was involved in the research, design, and commercialization of mass spectrometers for 37 years, and is a cofounder of the Finnigan Corporation. He was a member of previous NRC committees on commercial aviation security (1988-1993) and chaired the Panel on Test Protocol and Performance Criteria. 

The final goal of models used for testing or screening is to verify whether a special condition or feature is present or not. In this case the model system should be selected a priori based on scientific consensus and the testing protocols must be standardized in order to obtain comparable values when the same test is performed by two different laboratories or operators. Moreover, the existence of standardized methodologies could be very useful for regulators which need a certain degree of reliability to make appropriated decisions. 

A number of behavioral ratings scales and psychometric and performance tests, listed in Tables 20.16 to 20.18, are briefly summarized below, since many of these scales and tests may be used to evaluate safety as well as efficacy. The following comments on the tests provide only a few highlights readers who are interested in more details are advised to obtain additional information before choosing the tests that appear most relevant to be included in their particular protocol. 

The LC control software, either stand-alone or as part of an overall data-handling system, should be tested by means of a separate OQ protocol. This protocol only needs to address the communica-tions/control integrity of the hardware (e.g., setting up a run/sequence with the proper instrument parameters, the ability to start and stop the pump, etc.). It should cover all the required instrument control functions listed as part of the protocol s functional specifications. It does not need to include specific hardware performance testing, such as linearity or flow rate. The latter tests are performed separately, as part of the individual hardware validation described below. 

Facility personnel who perform testing and maintenance on fire protection equipment and systems must be trained, experienced, and knowledgeable in the systems and the protocols for testing and maintenance. Knowledge can include work history, educational experience, craft certification, manufacturer certification, field verification, and job assessment and testing. Facility person-... 

A significant challenge with using mist systems is determining whether the conditions of a particular manufacturer s limitation are representative of the actual conditions in which the system will be used. An engineering analysis should be performed to evaluate the significance of any variations between the actual fire hazard and the known performance capabilities of the water mist system. It is important that the test protocol contain these factors ... 

The pH, solubility, volatility, and stability of a substance in test vehicles can affect the performance of mutagenicity tests and therefore influence the design of test protocols. 

The 3T3 NRU test may easily be performed under GLP conditions in contract research organizations (CROs) and a high-throughput screening (HTS) method was recently reported in the literature. The HTS method produced no false positives, although some false negatives were observed, suggesting that the standard 3T3 NRU test protocol remains necessary for the final selection of nonphototoxic compounds [42]. 

The medical records of the volunteers who received cholinesterase-reactivating chemicals consisted of the test protocol, physicians orders, nursing notes (Including clinical observations), a checklist of symptoms, and laboratory and performance test results. The reports of physicians examinations and physical findings were generally not Included. Volunteers were identified by number. The Committee on Toxicology s assessment was based on records and summaries provided by the Department of the Army and NRC staff. The procedures were described fully in Volume 1. In most cases, the analysis was based on summaries of drug administrations prepared by a consultant to the Panel. 

Having chosen the analytical instrument or system, Installation Qualification, IQ, should be carried out to ensure that the equipment works the way the vendor or manufacturer specifies it should. IQ should be performed in accordance with a written test protocol with acceptance criteria with certification from the installation engineer, who is suitably qualified. Full written records of all testing carried out should be maintained as well as ensuring that adequate documentation and manuals have been supplied. The latter should include any Health Safety information from vendor or manufacturer. 

Evaluation of salt fog (ASTM B-117) and humidity resistance (ASTM D-2247) after 300 h of exposure was conducted on scribed panels of cold rolled steel (CRS), phosphatized steel, oily CRS, and aluminum. In accordance with test protocols, performance was rated from 2 to 10,2 representing the most extensive rusting and largest blisters and 10 representing the absence of any rust or blisters. Additionally, the frequency of the blisters was assessed by indicating dense (D), medium (M), or few (F). 

The PQ is the phase in which either a technical system is tested over a long period of time (e.g., water system), or a complex technical system is tested overall (connected filling line). For many systems OQ is the last phase performed during qualification. If there are only a few performance tests needed, it might be more practical to include them during OQ or process validation. Combining OQ and PQ decreases the number of documents (less documentation work in the future) and cuts approval time and effort. Again, the procedure for PQ is the same as for IQ and OQ ([develop PQ protocols, approve PQ protocols (by the quality assurance, production, and technical departments), perform PQ, work out the PQ report, and approve the PQ report (by the quality assurance, production, and technical departments)]. The documentation and test description are identical to those in the OQ phase. 

The Californian Collaborative for High Performance Schools requires contractors bidding for the construction of new schools and other public building projects to guarantee that they will only use materials whose emissions have been tested and certified by an accredited laboratory using the 01350 test protocol (see Table 6.1). 

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