Merit

The preceding definitions of economic potential and total annual cost can be simplified if it is accepted that they will be used to compare the relative merits of difierent structural options in the flowsheet and difierent settings of the operating parameters. Thus items which will be common to the options being compared can be neglected. 

The factor enabling interpolation of reduced properties of a pure compound or mixture between two reduced properties calculated on two reference fluids merits attention in order to understand its meaning. 

Two features in relation to the essential requirements merit further explanation, the so-called recognised third party organisations and the European approvals for materials. 

It may therefore be argued that the merit of conventional NDT using existing acceptance criteria is limited to the aspect of evaluating the welder s performance because this has always been the best we could. 

Micellar structure has been a subject of much discussion [104]. Early proposals for spherical [159] and lamellar [160] micelles may both have merit. A schematic of a spherical micelle and a unilamellar vesicle is shown in Fig. Xni-11. In addition to the most common spherical micelles, scattering and microscopy experiments have shown the existence of rodlike [161, 162], disklike [163], threadlike [132] and even quadmple-helix [164] structures. Lattice models (see Fig. XIII-12) by Leermakers and Scheutjens have confirmed and characterized the properties of spherical and membrane like micelles [165]. Similar analyses exist for micelles formed by diblock copolymers in a selective solvent [166]. Other shapes proposed include ellipsoidal [167] and a sphere-to-cylinder transition [168]. Fluorescence depolarization and NMR studies both point to a rather fluid micellar core consistent with the disorder implied by Fig. Xm-12. 

The sharpness of the frequency response of a resonant system is conunonly described by a factor of merit, called the quality factor, Q=v/Av. It may be obtained from a measurement of the frill width at half maxuuum Av, of the resonator frequency response curve obtained from a frequency sweep covering the resonance. The sensitivity of a system (proportional to the inverse of tlie minimum detectable number of paramagnetic centres in an EPR cavity) critically depends on the quality factor... 

Scattering and recoiling contribute to our knowledge of surface science tln-ough (i) elemental analysis, (ii) structural analysis and (iii) analysis of electron exchange probabilities. We will consider the merits of each of these tluee areas. 

Thus, when a large set of chemical reactions has to be investigated, an inductive learning process, deriving knowledge on chemical reactions and reactivity from a series of reactions, still has many merits. Such chemical knowledge can be put into models that then allow one to predict the course of new reactions. 

In view of this, early quantum mechanical approximations still merit interest, as they can provide quantitative data that can be correlated with observations on chemical reactivity. One of the most successful methods for explaining the course of chemical reactions is frontier molecular orbital (FMO) theory [5]. The course of a chemical reaction is rationali2ed on the basis of the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO), the frontier orbitals. Both the energy and the orbital coefficients of the HOMO and LUMO of the reactants are taken into account. 

The merit of the mathematical model [17] inherent in the BE- and R-matrices lies in the fact that it emphasized two essential points ... 

Such an analysis of the Hterature for assigning reaction types to different reaction schemes definitely has merits. However, it does not say anything about the importance of a reaction type, such as how frequently it is actually performed in the laboratory. 

It has already been said that the merits of a method for charge calculation can be assessed mainly by its usefulness in modeling experimental data. Charges from the PEOE procedure have been correlated with Cls-ESCA shifts [28], dipole moments [33], and NMR shifts [34], to name but a few. 

The reasons for this lack of work are manifold The problem is quite complex and difficult to tackle. The information in reaction databases is inherently biased only known reactions, no reactions that failed, are stored. However, any learning also needs information on situations where a certain event will not happen or will fad. The quality of information stored in reaction databases often leaves something to be desired reaction equations are incomplete, certain detads on a reaction are often incomplete or missing, the coverage of the reaction space is not homogeneous, etc. Nevertheless, the challenge is there and the merits of success should be great ... 

The method is incorporated into the CORA (Classification of Organic Reactions for Analysis) system [Sf Here, wc want to illustrate the merits of this approach by an example of its application to a specific problem, the prediction of the regioselec-tivity of a ring closure reaction. This is detailed in the following tutorial. 

Information-oriented systems are based on a Hbrary of known retro-reactions which have been collected and evaluated by a group of chemists while coding them in electronic form. In addition, information on the scope and the expected yield under various conditions, as well as a strategic merit, is usually stored. 

The Japanese program system AlPHOS is developed by Funatsu s group at Toyo-hashi Institute of Technology [40]. AlPHOS is an interactive system which performs the retrosynthetic analysis in a stepwise manner, determining at each step the synthesis precursors from the molecules of the preceding step. AlPHOS tries to combine the merits of a knowledge-based approach with those of a logic-centered approach. 

They then compared measured and predicted fluxes for diffusion experiments in the mixture He-N. The tests covered a range of pressures and a variety of compositions at the pellet faces but, like the model itself, they were confined to binary mixtures and isobaric conditions. Feng and Stewart [49] compared their models with isobaric flux measurements in binary mixtures and with some non-isobaric measurements in mixtures of helium and nitrogen, using data from a variety of sources. Unfortunately the information on experimental conditions provided in their paper is very sparse, so it is difficult to assess how broadly based are the conclusions they reached about the relative merits oi their different models. 

Method, There are two standard methods for the estimation of urea, (i) the hypobromite method, (ii) the urease method (p. 519). The chief merit of the hypobromite method is the rapidity of the analysis the results obtained are considered sufficiently accurate for most medical requirements, e.g., for the estimation of urea in urine. For accurate metabolic work, however, the urease method should be employed. 

The merits of the above contact rings for laboratory fractionating columns appear to have been overlooked. 

The main use of organocadmium compounds is for the preparation of ketones and keto-esters, and their special merit lies in the fact that they react vigorously with acid chlorides of all types but add sluggishly or not at all to multiple bonds (compare addition of Grignard reagents to carbonyl groups). Some t3rpical syntheses are ... 

Some reference to the use of nitrous acid merits mention here. Primary aromatic amines yield diazonium compounds, which may be coupled with phenols to yield highly-coloured azo dyes (see Section IV,100,(iii)). Secondary aromatic amines afford nitroso compounds, which give Liebermann a nitroso reaction Section IV,100,(v). Tertiary aromatic amines, of the type of dimethylaniline, yield p-nitroso derivatives see Section IV,100,(vii). ... 

The extensive work of Lubineau further demonstrated the merits of water with respect to the rates and selectivities of the Diels-Alder reaction. Since 1985 he has published a large number of articles dealirig mainly with dienes that were rendered water soluble through the temporary introduction of a... 

The merits of (enantioselective) Lewis-acid catalysis of Diels-Alder reactions in aqueous solution have been highlighted in Chapters 2 and 3. Both chapters focused on the Diels-Alder reaction of substituted 3-phenyl-1-(2-pyr idyl)-2-prop ene-1-one dienophiles. In this chapter the scope of Lewis-acid catalysis of Diels-Alder reactions in water is investigated. Some literature claims in this area are critically examined and requirements for ejfective Lewis-acid catalysis are formulated. Finally an attempt is made to extend the scope of Lewis-acid catalysis in water by making use of a strongly coordinating auxiliary. 

Artieles addressing the merits of varions optimization algorithms are... 

This chapter covers a number of concepts or properties that did not relate to material discussed in earlier chapters. Some of these techniques are seldom needed. Others just do not merit a chapter of their own because they are easy to apply. 

There are numerous articles and references on computational research studies. If none exist for the task at hand, the researcher may have to guess which method to use based on its assumptions. It is then prudent to perform a short study to verify the method s accuracy before applying it to an unknown. When an expert predicts an error or best method without the benefit of prior related research, he or she should have a fair amount of knowledge about available options A savvy researcher must know the merits and drawbacks of various methods and software packages in order to make an informed choice. The bibliography at the end of this chapter lists sources for reviewing accuracy data. Appendix A of this book provides short reviews of many software packages. 

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