Estrogen menopause

Schairer C et al. Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk. JAMA 2000 283 485-491. 

Oral post-menopausal estrogen replacement therapy increases circulating concentrations of C-reactive protein, but in 68 women who took a combination of transdermal 17-beta-estradiol and micronized progesterone there was no significant effect of transdermal estrogen on C-reactive protein concentrations compared with placebo (86). 

Femtrace Estrodiol acetate 0.45, 0.9, 1.8 mg Tablet Vasomotor symptom from menopause Estrogen receptor Povidone, lactose monohydrate, MCC, croscarmellose Na, silicon dioxide, magnesium stearate Warner Chilcott... 

Premarin Conjugated estrogens USP 0.3, 0.45, 0.625, 0.9, 1.25 mg Tablet Vasomotor symptom from the menopause Estrogen receptor Calcium phosphate tribasic, calcium sulfate, camauba wax, cellulose, glyceryl monooleate, lactose, magnesium stearate, hypromellose, glaze, PEG, stearic acid, sucrose, tinanium dioxide Wyeth... 

Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA (2008) Menopause, estrogen, and gonadotropins in Alzheimer s disease. Adv Clin Chem 45 139-153... 

Dupont WD, Page DL. Menopausal estrogen replacement therapy and breast cancer. Arch Intern Med 1991 151 67-72. 

Estrogenic agents, listed in Table 5, hasten sexual maturation in the female. The widest use of estrogens is in the treatment of the menopause. Estrogens are also used in the control of cancer of the prostate in the male. 

Women produce less estrogen after menopause. Estrogen inhibits calcium loss and bone erosion. Reduced estrogen levels result in more rapid calcium and bone loss. Osteoporosis can be minimized if adequate calcium intake occurs, especially from adolescence through young adulthood, and if estrogen replacements are taken after menopause. 

Pearce CL, Chung K, Pike MC, Wu AH. Increased ovarian cancer risk associated with menopausal estrogen therapy is reduced by adding a progestin. Cancer 2009 115 531-9. 

Since dietary cereals are low in sulfur-containing amino acids, they produce an alkaline urine which favors the retention of bone minerals. In post-menopausal women, there appears to be some interaction between the diet and the effect produced by estrogens on bone mineral content (28). 

In premenopausal women the ovary is the richest source of aromatase and hence estrogen. Aromatase is confined to the granulosa cells and is produced under the influence of gonadotropins (FSH and LH). Despite being a rich source of aromatase, three separate studies have shown that aromatase inhibitors are unable to sufficiently suppress ovarian estrogen production to postmenopausal levels. One explanation for this phenomenon may be a compensatory rise in gonadotrophins which maintains adequate estrogen production, despite the presence of the inhibitor. As such aromatase inhibitors cannot be used in premenopausal breast cancer patients. After menopause, ovarian... 

ERT is a clinical treatment whereby premenopausal estrogen levels are restored and the symptoms of menopause are relieved. 

Estrogens and progestins are diminished in menopausal or ovarectomized women. In hormone replacement therapy (HRT), these hormones are substituted to alleviate hot flushes, mood changes, sleep disorders, and osteoporosis. 

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