Database Medline

Figure 1.2 Journals that have published the most papers on combinatorial library design. Total number of papers published on this subject according to the Chemical Abstract Service s CAPLUS and MEDLINE databases for all years through 2004 plus three-quarters of 2005.

All of the science disciplines contribute to the body of information and knowledge that is used by pharmaceutical researchers, educators, and practitioners. Questions and information needs that arise within a pharmaceutical specialty will not necessarily be met by the literature associated with that specialty [13]. Researchers and academics particularly need access to a broad range of science literature. English is widely used however, the biomedical literature is and has been truly international [13]. About 86% of the current MEDLINE database is English language even though only 52% of current cited articles were published in the United States [20]. 

The aim of this chapter is to review the current knowledge on dairy food consumption and obesity-related chronic illness. Recent articles published in PubMed and Medline databases were critically appraised to describe the current knowledge and propose directions for future research. 

The PubMed site (http //www.ncbi.nlm.nih.gov/Entrez) is developed by the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), located at the National Institutes of Health (NIH). It has been developed in conjunction with publishers of biomedical literature as a search tool for accessing literature citations and linking to full-text journals at web sites of participating publishers. This site allows online access to the Medline database containing bibliographic citations and abstracts from journals dating back to 1966. 

Note SciFinder retrieves information contained in databases produced by Chemical Abstracts Service (CAS) as well as in the MEDLINE database of the National Library of Medicine (NLM). 

With the arrival of the World Wide Web and its ability to facilitate global communication came the opportunity to expand the services of the NLM. In 1997, the cumbersome methods of searching the MEDLINE database were replaced with user-friendlier search systems, namely Internet Grateful Med and PubMed. Moreover, searching via these resources was now free. These search systems fueled a 10-fold increase in the use of MEDLINE to 75 million searches annually. Today, more than 250 million MEDLINE searches are performed each year. In addition to MEDLINE, users can access almost any of the NLM databases from the NLM health information page, http //www.nlm.nih.gov/hinfo.html. 

MEDLINE is a bibliographic database that contains more than 11 million references to journal articles from 4300 national and international biomedical journals, covering the period from 1966 to the present.Types of journals indexed in MEDLINE include pharmacy, allied health, nursing, medicine, veterinary medicine, dentistry, pre-clinical science, and life science journals. Each week, nearly 8000 reference citations, created by the NLM and its partners, are added to the MEDLINE database. 

Provision of free access to the MEDLINE database Development of... 

MEDLINE database, known as PubMed on the NLM platform, is available free worldwide, and is considered the premier source for searching the clinical medical literature back to 1966. Embase is the other key clinical database, produced by Elsevier and known for its international scope and exceptional coverage of the drug literature. 

Proteomics is a newly coined term that refers to the field of study of the proteome. The term was defined for the first time in 1994 as the PROTEin products of a genOME. Since its introduction, the term has found widespread acceptance across the breadth of biological research. A simple search of the Medline database circa October 2000 indicated an almost exponential increase in the number of published articles about proteomics (see Eigure 9.1) since 1995. 

FIGURE 2.23 Number of studies utilizing the MAE technique during the last 7 years. (Source CALPUS and MEDLINE databases.)... 

A large-scale retrospective study of the literature over the period 1966 to 1996 using the Medline database identified 41 cases of neurotoxic adverse effects in 41 patients with low therapeutic concentrations of lithium. Of these patients, 10 were taking haloperidol. ... 

Use Core 3 functions, once you have PubMed XML file with all records searched for malaria keyword (pubmed.xml) to load data into citation table of medline database programmatically. 

Because of the potential to revolutionize treatment of a broad range of human diseases, including some of mankind s most-hated and currently intractable afflictions, gene therapy has been heavily investigated over the past decade. More than 17,000 papers containing the keywords gene therapy have appeared in the MEDLINE database since 1990. The first gene therapy clinical trial, for... 

The data to support this suboptimal use of TLC is reflected by literature search information on the complete Medline Database from 1966 to the present (December, 1994 Table 1). Even accounting for flawed bibliographic citation either by the investigators or library scientists (7) the numbers on the TLC of nucleic acids remain small. Sherma s timely reviews of TLC and our personal discussions further support this contention, by reviewing all data on nucleic acids in one brief paragraph (8). 

Data on the mechanisms of vestibular toxicity and its development in association with aminoglycoside exposure have been extracted from the MEDLINE database and summarized [2 ]. For similarly designed studies the pooled incidence of vestibular toxicity was 11% for gentamicin, 7.4% for amikacin, 3.5% for tobramycin, and 1.1% for netilmicin. The underlying mechanism appears to be excessive production of oxidative free radicals, a time-dependent mechanism, but not apparently related to dose or serum concentration. 

Repository for publications on medical and health topics, manages MEDLINE database. 

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