Marijuana hashish

The most common illicit dmgs ia the United States today are heroin, cocaine, marijuana, hashish, phenycHdine, LSD, and methamphetamine. These make up at least 90% of the total dmgs seized. 

The simple pyrans are rather unstable compounds and of little biological or industrial significance but some of their benzo derivatives are of considerable interest. Many 2H-1-benzopyrans (chromenes) are found in plants, for example evodionol (126), lapachenole (127), lonchocarpin (128), rottlerine (129) and edulan (130). A few of the constituents of marijuana (hashish) belong to this class, for example cannabinol (131). 

The resin secreted by Cannabis indica and Cannabis sativa, varieties of hemp, is known variously as marijuana, hashish or bhang and is abused as a hallucinogenic drug. It appears however to have some beneficial properties and is currently under test as an antiemetic in cancer therapy. The secretion contains a number of interrelated oxygen heterocycles, some of which are shown in Scheme 281, which attempts to indicate their biosynthetic relationships (70MI22401). The cannabinoids are probably derived from a monoterpene unit based on p-menthane and 5-n-pentylresorcinol (olivetol), acting the part of a polyketide. 2,2-Dimethylchromene biosynthesis also requires the intervention of an isoprene fragment. 

A9-Tetrahydrocannabinol (A9-THC) is considered to be the predominant compound in preparations of C. sativa (marijuana, hashish, bhang) that is responsible for the central nervous system effects in humans. The recognized central nervous system responses to these preparations include alterations in cognition and memory, euphoria, and sedation. Potential therapeutic applications of cannabis preparations that are of either historical or contemporary interest include analgesia, attenuation of the nausea and vomiting of cancer chemotherapy, appetite stimulation, decreased intestinal motility of diarrhea, decreased bronchial constriction of asthma, decreased intraocular pressure of glaucoma, antirheumatic and antipyretic actions, and treatment of convulsant disorders. These effects have been reviewed recently (Howlett, 1995). 

Each year, the National Household Survey on Drug Abuse (NHSDA), conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA) of the United States Department of Health and Human Services, collects statistical data on five drug groups, including marijuana/hashish, psychotherapeutic drugs, cocaine/crack, hallucinogens, and inhalants. The med-... 

In looking at how inhalant abuse compares to other drug use, the MTF study found that among eighth graders, 9.1% reported they had used inhalant the previous year, while 41.9% used alcohol, 15.4% reported marijuana/hashish use and 12.2% used cigarettes. 

Does not include marijuana, hashish, or hash oil SOURCE Drag Enforcement Agency, ... 

Halazepam see Benzodiazepine Halcion see Benzodiazepine Haldol see Tranquilizers Haloperidol see Tranquilizers Halothane see Inhalants Halotussin DM see Dextromethorphan Hardhay see Herbal drugs Hardware see Inhalants Hash see Marijuana Hash oil see Marijuana Hashish see Marijuana Hashish oil see Marijuana Hat man see Heroin... 

Any Illicit Drug refers to marijuana/hashish, cocaine (including crack), heroin, hallucinogens (including LSD and POP), inhalants, or any prescription-type psychotherapeutic used nonmedically. 

The human data, as well as the animal studies indicate that cannabinoids may ameliorate some symptoms of MS. Unfortunately, a definitive large-scale study has yet to be performed. Such a study should take into account that (a) the placebo effect in MS is very high (b) the effective doses recorded are close to, or identical with the doses that cause cannabimimetic effects (c) cannabis (marijuana, hashish) is obviously not identical to zf9-THC, and that other constituents may synergize THC action (d) smoking cannot be compared with oral administration, and (e) the anal route of administration [141] may be a preferred one. 

National survey data show that people in the United States use a variety of drugs. Alcohol, tobacco cigarettes, and marijuana/hashish consistently have appeared as the most commonly tried and currently used psychoactive drugs. 

The main psychotropically active compounds present in Cannabis saliva or in its preparations (marijuana, hashish, etc.) is (3R,4R)-(-)-Al -THC (I). Occasionally small quantities of the compound (3R,4R)-(-)-A6 -THC (II) are found. Both compounds have a pronounced activity on mammals and on humans, producing the typical cannabis effect. This effect can be measured in animals in a quantitative manner by various tests, two of these being the monkey test, Grunfeld et al., Psychopharmacol. 14, 200 (1969) and by the ring test, Pertwee, Brit. J. Pharmacol. 46, 753 (1972). In the monkey test the minimum giving an effect is 50ug./kg of the (3R,4R)-(-)-Al-THC while that of (3R,4R)-(-)-A6 -THC is 0.1 to 0.25 mg/kg. 

Cannabis (eg, marijuana, hashish) Impaired motor coordination, anxiety, slowed reaction time, impaired judgment, conjunctival injection, dry mouth, increased appetite( JWluCin Kwa None Inhibitory G protein, GABA, increased serotonin Abstinence and support Respiratory effects, amotivational syndrome, increased inddence of mental illness... 

Assemble the apparatus described add the marijuana, hashish or hash oil the solvent and the acid seal and reflux (i.e., heat gently) for about one hour. You can expect about 90% of the CBD to isomerize to A THC if an organic solvent such as benzene or petroleum ether is used, but only about 60% yield of A and A THC s with other products (e.g., ethoxyhexahy-drocannibinols) if ethanol or another alcohol is used. If the can-nabinoids have already been extracted i.e., if you have hash oil, you may simply dissolve the oil in solvent and heat with acid to get isomerization. For example, a saturated solution of paratoluenesulfonic acid in methylene chloride heated at 80 F for 45 minutes gives about 90% yield of THC. As the reaction times are increased, more A THC will isomerize to A THC, but since the two have nearly the same activity, this does not matter. For oil, use about 5 ml oil per 100 ml solvent. 

Cannabis (marijuana, hashish). The main active consiitucfli of cannabis is A -letrahydrocannabinol (THC). Cannabis has both hallucinogenic and depressant actions. It produces feelings of euphoria, relaxation and well-being. Cannabis is not dangerously addictive, but at least mild degrees of dependence may occur. Cannabis may cause acute psychotoxic effects that in some way.s resemble an LSD bad trip. ... 

Marijuana/hashish These are cannabis drugs that seem to act as a CNS depressant. The effects are mental relaxation and euphoria and decreased inhibitions. 

Synonyms cannabis marijuana hashish lysergic acid [Pg.156]

Marijuana (hashish, Mary Jane, pot, grass). Cannabis sativa... 

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