Neoplasms malignant

CARCINOGEN An agent (whetlier ehemieal, physieal or biologieal) eapable of inereasing the ineidenee of malignant neoplasms. Defined in Regulation 2 of the Control of Substanees Hazardous to Health Regulations 1999 as ... 

Latency refers to the period of time that elapses between the first contact of a harmful agent and a host, and the development of identifiable symptoms or disease. Latency may be as short as a few hours, the time required for photochemical smog to induce watery eyes. Or it may stretch to 20 - 30 years for a chronic condition such as asbestosis or malignant neoplasm of the lung. The association between a gi en e.xposure and a disease is all that more difficult because of the passage of time. 

Generally, most antineoplastic drugs affect cells that rapidly proliferate (divide and reproduce). Malignant neoplasms or cancerous tumors usually consist of rap-... 

CARCINOGEN An agent (whether chemical, physical or biological) capable of increasing the incidence of malignant neoplasms. 

HENNEKENS c H, BURNING J E, MANSON J E and STAMPFER M (1996) Lack of effect of long-term supplementation with beta-carotene on the incidence of malignant neoplasms and cardiovascular disease . New Engl J Med, 334, 1145. 

The most common adverse effect with omalizumab is injection-site reaction, reported in 45% of patients in clinical trials. Other adverse effects include viral and upper respiratory tract infections, sinusitis, headache, and pharyngitis. Rare cases of malignant neoplasms and anaphylaxis were reported during clinical trials of omalizumab in asthma. Patients should be monitored for at least 2 hours following the injection so that anaphylaxis and/or injection-site reactions may be managed.25... 

Long-term survivors of HCT should be monitored closely, particularly for infections and secondary malignant neoplasms. 

Carcinoma—Malignant neoplasm composed of epithelial cells, regardless of their derivation. 

Cocco et al. (1997) evaluated cause-specific mortality among workers of a lead-smelting plant in Italy. The cohort consisted of 1,388 men whose vital status was followed from January 1950, or 12 months after the date of hiring, whichever was later, through December 1992. For this period, reference mortality rates of the Italian male population were available from the mortality data base of the World Health Organization (WHO). The deaths from all causes, all malignant neoplasms, diseases of the... 

The results were that income inequality was strongly associated with lack of social trust, and that states with high levels of social mistrust had higher age-adjusted rates of total mortality (level of social trust explained 18% of variance in total mortality, under their regression). Lower levels of social trust were associated with higher rates of most major causes of death, including coronary heart disease, malignant neoplasms, cerebrovascular disease, unintentional injury, and infant mortality. 

On the other hand, per capita group membership was strongly inversely correlated with all-cause mortality. Level of group membership was also a predictor of coronary heart disease, malignant neoplasms, and infant mortality. 

Knekt P, Jarvinen R, Seppanen R, Hellovaara M, Teppo L, Pukkala E and Aromaa A. 1997. Dietary flavonoids and the risk of lung cancer and other malignant neoplasms. Am J Epidemiol 146(3) 223-230. 

Colorectal cancer is a malignant neoplasm involving the colon, rectum, and anal canal. 

Prostate cancer is a malignant neoplasm that arises from the prostate gland. Prostate cancer has an indolent course localized prostate cancer is curable by surgery or radiation therapy but advanced prostate cancer is not yet curable. 

The detection of monoclonality in immnnoglobnlin-producing neoplasms as mentioned above The presence of either, bnt not both, k or 7. light chain in lymphocytic proliferations may indicate the presence of a malignant neoplasm snch as B-cell lymphoma or myeloma/plasmacytoma. 

MOSH considers 3,3 -dichlorobenzidine a potential occupational carcinogen and recommends workplace practices and controls to reduce exposures to the lowest possible level. MOSH defines potential occupational carcinogens as substances which may cause an increased incidence of benign and/or malignant neoplasm, or a substantial decrease in the latency period between exposure and onset of neoplasms in humans. 

---