Listeria monocytogenes infection treatment

Youssef, M. Eattal, E. Alonso, M.J. Roblot-Treupel, L. Sauzieres, J. Tancrede, C. Omnes, A. Couvreur, P. Andremont, A. Effectiveness of nanoparticle-bound ampi-cillin in the treatment of listeria monocytogenes infection in athymic nude mice. Antimicrob. Agents Chemother. 1988, 32, 1204-1207. 

Slifinan NR, Gershon SK, Lee JH et al. Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents. Arthritis Rheum 2003 48(2) 319-324. 

The mice were infected i.v. with 2 x 10 Listeria monocytogenes. EPS-treatment was carried... 

Chloroquine (Aralen) is also used in die treatment of extraintestinal amebiasis (see section on Amebicides). Doxycycline is also used to treat infections caused by Neisseria gonorrhoeae, Treponema pallidum, Listeria monocytogenes, Clostridium, and Bacillus anthracis when penicillin is contraindicated. Quinine also may be used for die prevention and treatment of nocturnal leg cramps. 

Bakker-Woudenberg lAJM, Lokerse AF, Roerdnik FH, et al. Free versus liposome-entrapped ampicillin in treatment of infection due to listeria monocytogenes in normal and athymic (nude) mice. J Infect Dis 1985 151 917-924. 

The presence of diphtheroid-like gram-positive rods in the cerebrospinal fluid smear of an 82-year-old patient is indicative of the presence of Listeria monocytogenes. In addition to their role as a potential causative agent in neonatal meningitis, listeria infections are more common in elderly patients and in those who have been treated with immunosuppressive agents. Treatment consists of ampicillin with or without gentamicin. Resistant strains are rare. The answer is (A). 

Trimethoprim and sulfamethoxazole (TMP-SMZ) This important drug combination is currently accepted treatment for complicated urinary tract infections and for respiratory, ear, and sinus infections due to H influenzae and Moraxella catarrhalis. In the immunocompromised patient, TMP-SMZ is used for infections due to Aeromonas hydrophila and is the drug of choice for prevention and treatment of pneumocystis pneumonia. TMP-SMZ is a possible backup drug for typhoid fever and shigellosis and has been used in the treatment of infections caused by methicillin-resistant staphylococci and Listeria monocytogenes. 

We demonstrated that oral administration of CVE caused the retention of the capacity of MAIDS mice to eliminate L.monocytogenes in association with an improvement of the defective immune response to L. monocytogenes. CVE is somewhat effective in the treatment of opportunistic Listeria infections in immuno-deficient mice. 

Listeria A genus of rod-shaped aerobic motile Gram-positive bacteria. Only one species, L. monocytogenes, causes disease (listeriosis). It is resistant to physical and chemical treatments and can occur as a contaminant in certain foods, in faeces, etc. Listeriosis can take various forms, depending on the site of infection localization in the central nervous system causes meningo-encephaUtis, while uterine infection can result in abortion or congenital handicap in the fetus. 

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