Diseases causes

Pellagra is a disease caused by a deficiency of niacm (C6FI5NO2) in the diet Niacin can be synthesized in the laboratory by the side chain oxidation of 3 methylpyndine with chromic acid or potassium permanganate Suggest a reasonable structure for niacin... 

Secondary immunodeficiencies (9) are much more common than primary ones and frequently occur as a result of immaturity of the immune system in premature infants, immunosuppressive therapy, or surgery and trauma. Illnesses, particularly when prolonged and serious, have been associated with secondary immunodeficiencies, some of which may be reversible. Acquked immune deficiency syndrome (AIDS) (10—12) may be considered a secondary immunodeficiency disease caused by the human immunodeficiency vimses HIV-1 or HIV-2. Hitherto unknown, the disease began to spread in the United States during the latter part of the 1970s. The agent responsible for this infection has been isolated and identified as a retrovims. 

Pa.g et s Disease of Bone. Paget s disease, osteitis deformans, occurs mainly ia people over 40. About twice as many men as women are affected. The disease, caused by faulty utilisation of may be mild and asymptomatic requiring Httle or no treatment. Clinical signs are high alkaline phosphatase and high urine hydroxyproline as weU as abnormal bone stmcture which usually goes unrecognised until discovered accidentally by routine x-ray examination (32). 

Florfenicol (2) has been approved in Japan for the treatment of pseudo-tuberculosis caused by Pasteurellapiscicida and streptococcosis m. yeUowtail fish. The recommended dose is 10 mg/kg for up to one week and the drug withdrawal time is five days after cessation of treatment. Florfenicol is active in bovine respiratory disease caused by Pasteurella species and mastitis caused by Staphylococci and Streptococci. It is also effective in neonatal cohbacillosis caused by E. coli. The drug is being developed worldwide by Schering-Plough Animal Health for the treatment of aquatic and bovine diseases. 

This article discusses the main diseases caused by protozoa and the important chemotherapeutic antiprotozoal agents currently ia use or ia an advanced state of development. Not all alternative proprietary names are given for each dmg. There are excellent sourcebooks on protozoology and parasitology (2—8). 

There are other milder forms of thederiasis that resemble the disease caused by T parva infection. They also primarily affect catde and are transmitted by ticks. Causative organisms iaclude Theileria annulata responsible for tropical thieleriasis, tropical piroplasmosis, Egyptian fever, and Mediterranean Coast fever. These affect ox, zebu, and water buffalo. Endemic areas iaclude northern Africa, southeastern Europe, the southern part of the former USSR, and Asia. Theileria mutans is the cause of benign bovine thieleriasis, Marico calf disease, and mild gad sickness. It affects ox and zebu ia Africa, Asia, southern Europe, England, the former USSR, AustraUa, and North America. 

Bismuth subsahcylate [14882-18-9] Pepto-Bismol, is a basic salt of varying composition, corresponding approximately to i9-H0CgH4C02(Bi0). Like a number of other insoluble bismuth preparations, it is not currentiy approved in the United States for the treatment of peptic ulcer disease but is under active investigation for this purpose (180). It does appear to be effective for the rehef of mild diarrhea and for the prevention of travelers diarrhea (181). The ready availabiUty of this dmg, however, may lead to its ovemse and result in toxic effects caused by both the saUcylate and bismuth components. It has been suggested that bismuth subsahcylate is somewhat effective in the symptomatic treatment of isosporiasis, a disease caused by the intracellular parasite Isospora belli (182). 

HAZARDOUS MATERIALS (SUBSTANCES/WASTES) A hazardous material is any substance that causes or may cause adverse affects on the health or safety of employees, the general public, or the environment any biological agent and other disease-causing agent, or a waste or combination of wastes. 

Turbidity n/a Tt3 Turbidity, a measure of water cloudiness, is used to indicate water quality and filtration effectiveness (e.g., whether disease-causing organisms are present). Higher turbidity is associated with higher levels of microorganisms such as viruses, parasites and some bacteria. These organisms can cause symptoms such as nausea, cramps, diarrhea, and associated headaches. Soil runoff... 

No more than 5.0% samples total coliform-positive in a month, (For water systems that collect fewer than 40 routine samples per month, no more than one sample can be total coliform-positive). Every sample that has total coliforms must be analyzed for fecal coliforms. There may not be any fecal coliforms or E. coli. Fecal coliform and E. coli are bacteria whose presence indicates that the water may be contaminated with human or animal wastes. Disease-causing microbes (pathogens) in these wastes can cause diarrhea, cramps, nausea, headaches, or other symptoms. These pathogens may pose a special health risk for infants, young children, and people with severely compromised immune systems. 

Disinfection The process designed to kill most microorganisms in wastewater, including essentially all pathogenic (disease-causing) bacteria. There are several ways to disinfect, with chlorine being the most frequently used in water and wastewater treatment plants. 

Toxin A substance produced in some cases by disease-causing microorganisms, which is toxic to other living cells. 

Asbestosis A disease caused by the inhalation of asbestos fibers. 

Chlorinated water. The oxidizing power of chlorine-containing chemicals keeps swimming pool watar free of disease-causing microorganisms. 

Which difference could account for the fact that a diver is much less likely to suffer from the bends if he breathes a mixture of 80% helium and 20% oxygen than if he breathes air (The bends is a painful, sometimes fatal, disease caused by the formation of gas bubbles in the veins and consequent interruption of blood flow. The bubbles form from gas dissolved in the blood at high pressure.)... 

AIDS (acquired immunodeficiency syndrome) is the final stage of disease caused by infection with HIV. In this stage, the vims infection has severely affected the immune system, causing a depletion of CD4+ T-helper cells. AIDS is characterized by the manifestation of typical diseases caused by opportunistic infections (Pneumocystis carinii pneumonia, CMV retinitis, candidiasis of the esophagus, cerebral toxoplasmosis), neurological manifestations, cachexia, or certain tumors (Kaposi sarcoma of the skin, B-cell lymphoma). 

Antimicrobial drugs are used for the treatment of diseases caused by microorganisms (bacterial or viral infections). 

Botulism is a disease caused by ingestion of foods contaminated with Clostridium botulinum (food-borne botulism) or, very rarely, by wound infection (wound botulism) or colonization of the intestinal tract with Clostridium botulinum (infant botulism). The toxins block the release of acetylcholine. Botulism is characterized by generalized muscular weakness, which first affects eye and throat muscles and later extends to all skeletal muscles. Flaccid paralysis can lead to respiratory failure. 

Vector-born infectious disease caused by Trypanosoma cruzi. 

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