Aeromonas hydrophila

Amphibians. Immunosuppression has been shown to occur during metamorphosis in several amphibians, and appears to be hormonally regulated. The disappearance of 11 populations of toad from Colorado was associated with immune suppression, and frog mortalities have been associated with infection by a commonly occurring bacteria, Aeromonas hydrophila the cause of the immunosuppression in these animals has not been elucidated. " ... 

Aeromonas hydrophila is a bacterium that causes diarrheal diseases and deep wound infections. These complications arise due to pore formation in sensitive cells by the protein toxin aerolysin. Proteolytic processing of the 52-kD precursor proaerolysin (Figure 10.34) produces the toxic form of the protein, aerolysin. Like a-hemolysin, aerolysin monomers associate to form a heptameric transmembrane pore. Michael Parker and coworkers have proposed... 

FIGURE 10.34 The structure of proaerolysiu, produced by Aeromonas hydrophila. 

Studies on S-layers present on the cell envelopes of a great variety of pathogenic organisms [100] revealed that these crystalhne arrays can represent important virulence factors. Most detailed studies have been performed on the fish pathogenic bacteria Aeromonas salmonicida and Aeromonas hydrophila [102] and the human pathogen Campylobacter fetus uh p. fetus [103] and Bacillus anthracis [104]. For example, whole-cell preparations or partially purified cell products are currently used as attenuated vaccines against various fish pathogens [102,105]. 

Three 3-amino-3,6-dideoxyhexoses, having the d- and L gluco and D-ga-lacto configurations, have been found. The two D-sugars are not very common, but occur in some 0-antigens for example, those from E. coli 0114 (Ref. 60) and E. coli 02 (Ref 61), respectively. The D-galacto isomer has also been found in the cell-wall polysaccharide from Eubacterium saburreum strain L13.3-Amino-3,6-dideoxy-L-glucose has been found in the core part of the Aeromonas hydrophila chemotype 111 LPS. 

Van der Kooij D, A Visser, JP Oranje (1980) Growth of Aeromonas hydrophila at low concentrations of substrates added to tap water. Appl Environ Microbiol 39 1198-1204. 

Figure 5.6 Successful transformation of Aeromonas hydrophila raw spectra A acquired on day 27 to new locations a (relationship indicated with a dotted arrow) near an A. hydrophila day 1 library spectrum C using another day 27 bacterium, E. coli 1090 D as reference compared to its own day 1 E. coli 1090 Library spectrum L (relationship indicated with a solid arrow).

Idaka E, Ogawa T, Sakaguchi M et al (1979) Isolation and identification of an azo dye assimilating bacterium I Aeromonas hydrophila var 24B. Res Rept Fac Eng Gifu Univ 29 65-67... 

Aeromonas hydrophila, Comamonas testosterone, Acinetobacter baumannii Red rbn Fluidized bed Continuous... 

Snarski, V.M. 1992. The response of rainbow trout Salmo gairdneri to Aeromonas hydrophila after sublethal exposures to PCB and copper. Environ. Pollut. 28A 219-232. 

Investigations of pure cultures of bacteria clearly show the existence of a threshold concentration for the carbon source below which replication does not occur. This value is about 18 pg/1 for Escherichia coli and Pseudomonas sp. growing on glucose, 180 pg/1 for Aeromonas hydrophila growing on starch,... 

Biscardi D, Castaldo A, Gualillo O et al (2002) The occurrence of cytotoxic Aeromonas hydrophila strains in Italian mineral and thermal waters. Sci Total Environ 292(3) 255-263... 

Telford JR, Leary JA, Tunstad LMG, Byers BR, Raymond KN (1994) Amonabactin Characterization of a Series of Siderophores from Aeromonas hydrophila. J Am Chem Soc 116 4499... 

Telford JR, Raymond KN (1998) Coordination Chemistry of the Amonabactins, Bis(cate-cholate) Siderophores from Aeromonas hydrophila. friorg Chem 37 4578... 

LC50 at 30-32 mg CaCOj/L No adverse effects no altered susceptibility to Aeromonas hydrophila infections... 

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