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Injection Slit

This etched structure is used to optimize and automate the injection procedure for shear-driven systems. Instead of injecting the sample by introducing it in front of the channel, an etched structure (injection slit) stands perpendicular toward the flow direction and the... [Pg.1402]

Schematic overview of the detection groove structure. In the nanochannel structure (7-2), a deeper groove (i) is etched to enhance the detection. With this type of groove (with a depth of 4.75 pm see side view), a fivefold decrease in the detection limit could be obtained, (b) Outline of the automated injection system, (a) The supply channels in the PMMA connect to a cavity above the injection micro-well, (b) Wyko (optical profilometry) scan of the backside of the etched well, showing the position of the injection slit in the channel, together with the non-etched channel spacer regions (7, 2) delimiting the lateral extent of the channel and the non-etched region (3) preventing the mobile phase that is present in front of the channel to enter the channel. The flow direction is indicated by the arrows... Schematic overview of the detection groove structure. In the nanochannel structure (7-2), a deeper groove (i) is etched to enhance the detection. With this type of groove (with a depth of 4.75 pm see side view), a fivefold decrease in the detection limit could be obtained, (b) Outline of the automated injection system, (a) The supply channels in the PMMA connect to a cavity above the injection micro-well, (b) Wyko (optical profilometry) scan of the backside of the etched well, showing the position of the injection slit in the channel, together with the non-etched channel spacer regions (7, 2) delimiting the lateral extent of the channel and the non-etched region (3) preventing the mobile phase that is present in front of the channel to enter the channel. The flow direction is indicated by the arrows...
An injection slit etched by Bosch avoids any formation of asymmetrically shaped plugs, which typically occurs during loading of the sample in wide channels. The slit is cormected to a vacuum system and syringes for the supply of the analyte and the mobile phase. A CFD simulation was first performed to compare different injection well shapes and configurations in order to account for less profitable configurations. [Pg.2984]

There are otlier teclmiques for mass separation such as tire quadmpole mass filter and Wien filter. Anotlier mass spectrometry teclmique is based on ion chromatography, which is also capable of measuring tire shapes of clusters [30, 31]. In tills metliod, cluster ions of a given mass are injected into a drift tube witli well-defined entrance and exit slits and filled witli an inert gas. The clusters drift tlirough tills tube under a weak electric potential. Since the... [Pg.2390]

Processing and Application. Polystyrene and the other thermoplastics would not have been able to enter on their triumphal march if the manufacturers of processing equipment had not been able to provide efficient fabrication methods. A decisive factor was that between 1950 and 1960 the injection molding machine with a screw preplasticizer was developed and extrusion through slit dies to give sheeting or film followed by thermoforming was evolved. [Pg.273]

Taylor s dispersion is one of the most well-known examples of the role of transport in dispersing a flow carrying a dissolved solute. The simplest setting for observing it is the injection of a solute into a slit channel. The solute is transported by Poiseuille s flow. In fact this problem could be studied in three distinct regimes (a) diffusion-dominated mixing, (b) Taylor dispersion-mediated mixing and (c) chaotic advection. [Pg.2]

In 1969, 31 subjects had ocular Instillations of either 0.12 or 0.25X CS In water with 0.5X polyaorbate 20 or 0.05- 1.0Z CS In trioctyl phosphate In their right eyes. The subjects experienced intense ocular Irritation and lacrlmatlon. Acute conjunctival Injection lasted 1 h. No fluorescein staining of the cornea was seen under ultraviolet Illumination. In one subject, corneal staining, visualized with the slit lamp, resolved In 24 h.34 35... [Pg.165]

When a PTV instead of a classic injector was utilized in the analysis of penicillin residues, the sensitivity and the precision of the analysis were markedly improved (45). With the cooled PTV injector, some microliters could be injected, and the split-splitless mode allowed solvent venting at low injector temperatures with open slit in a first step, and quantitative transfer of volatile or derivatized drugs by a freely selected linear heat-up rate between 2-12 C/s in the splitless mode in the second step. Sensitivity could be enhanced by multiple injections before heat-up. Nonvolatile components of a sample did not contaminate the chromatographic system, since they accumulated in the glass vaporization tube, which could be changed easily. [Pg.673]

At this stage, one has to take into account the volume compressibility of the material, since upon feed-up the hold-on time of material under pressure is determined by compressibility and slow viscous flow. If the pressure of injection PQ is sufficiently high, then at this stage a liquid may be considered to be Newtonian with viscosity q ,. Keeping this in mind, we may state that the calculation given below will be applicable to various plastisols (of types I and II) with the only difference that for plastisol I q = const, while for plastisol II q = q. For the sake of simplicity, the analysis will be performed for the case of a flat mould filled through a slit runner (Fig. 10 a). [Pg.115]

As in Sect. 6.1, let us consider the injection moulding of a long thin plate through a slit runner, neglecting the resistance of the runner. Then Eqs. (4.12), (5.11), (5.12) for pressure distribution P(z, t), the motion of the averaged flow front h(t), and filling time will have the form ... [Pg.123]

Capillary Viscometer. The end products from the liquid mixtures are usually obtained by extruding the liquid mass through narrow tubes or slits (e.g., spinning of fibers, injection molding, or film extrusion). Therefore, the pressure flow through a capillary is of technological interest. Hence, we analyzed the flow of a liquid mixture through a capillary with circular cross-section and compared the results of theory and measurement. [Pg.74]

The most severe side effects, which may occur during SLIT, consist of the allergic symptoms themselves such as allergic rhinitis, asthma attacks or atopic eczema [31]. Anaphylactic reactions are not expected, because allergens do not penetrate the mucosa in an unlimited way, thus entering blood vessels, as is possible after injections. [Pg.49]


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See also in sourсe #XX -- [ Pg.826 ]




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