Immune modulator

Hata AN, Breyer RM (2004) Pharmacology and signaling of prostaglandin receptors Multiple roles in inflammation and immune modulation. Pharmacol Ther 103 147-166... [Pg.1005]

Cholera toxin and related toxins act as immune modulators, with potential use as adjuvants and as therapeutic agents in the treatment of immunologically mediated human disease. [Pg.490]

Inflammatory response genes t Immune modulation genes T... [Pg.235]

Thienoimidazothiazole 34 and two isomers were synthesized <1998JHC923> as thiophene analogues of the immune modulator TILOMISOL by cyclizing appropriate 3-oxo thioethers of thienoimidazoles. In contrast to the benzene analogue, no intermediates were observed at this step. [Pg.686]

Bouic PJD and Lamprecht JH. 1999. Plant sterols and sterolins a review of their immune-modulating properties. Altern Med Rev 4(3) 170-177. [Pg.265]

Raz, I., Eldor, R., and Naparstek, Y., Immune modulation for prevention of type I diabetes mellitus, Trends Biotechnol., 23, 128, 2005. [Pg.61]

Immune Modulation byTCDD and Related Polyhalogenated Aromatic Hydrocarbons... [Pg.239]

Pestka, J. J. et al. Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes Unraveling a paradox. Toxicol. Lett. 153, 61, 2004. [Pg.301]

The sympathetic nervous system (SNS) and the hypothalamic-pituitary axis work together as important modulators of the immune system after exposure to stressors. Norepinephrine (NE) and epinephrine (EPI) (catecholamines from the SNS) and neuroendocrine hormones modulate a range of immune cell activities, including cell proliferation, cytokine and antibody production, lytic activity, and migration. This chapter will focus on these two major pathways of brain-immune signaling, briefly summarizing the evidence for SNS and hypothalamic-pituitary-adrenal (HPA) modulation of immune function, their influence on immune-mediated diseases, immune modulation in aging, and early life influences on these pathways. [Pg.490]

Awareness of immunotoxicology was stimulated by a comprehensive review by Vos in 1977, in which he provided evidence that a broad spectrum of xenobiotics alter immune responses in laboratory animals and subsequently may affect the health of exposed individuals. Several additional reviews, as well as national and international scientific meetings, have reinforced these early observations. In several studies, alteration of immune function was accompanied by increased susceptibility to challenge with infectious agents or transplantable tumor cells, indicating the resulting immune dysfunction in altered host resistance. Clinical studies in humans exposed to xenobiotics have confirmed the parallelism with immune dysfunction observed in rodents. The latter sections in this volume describe studies with xenobiotics that resulted in immune modulation in rodents and man. [Pg.667]

Vasoactive Intestinal VIP, (VPAC,) Human cDNA Asthma, hypertension, gastrointestinal disorders, inflammation, septic shock, diabetes Relaxation of smooth muscle, immune modulator, neuroprotection... [Pg.123]

Androgen AR Human cell line Cancer, andropause, menopause, Sjogren s syndrome, idiopathic hirsutism, infertility, hypertension, mood disorders, diabetes, cystic fibrosis Immune modulation, vascular hemodynamics, neuroprotection, skeletal development, reproduction, maintenance of neuronal morphology, regulation of vasopressin Vla expression, prostatic blood flow and LH production... [Pg.124]

Kaminski NE, Abood ME, Kessler FK, Martin BR, Schatz AR. (1992). Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation. Mol Pharmacol. 42(5) 736-42. [Pg.561]

Development of a Liposomal Vaccination System for Immunity-Modulating Antitumor Therapy... [Pg.207]

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