HPV chemicals program

Work undertaken on a chemical in the OECD HPV Chemicals Program as a follow-up to conclusions and recommendations by SIAM is considered as post-SIDS work, see also Table 2.2. This can include national/regional exposure information gathering and assessment as well as testing of endpoints beyond SIDS to assess a concern identified by SIAM. The Task Force on Existing Chemicals monitors post-SIDS work and can take decisions related to further work to be carried out in OECD in a concerted manner. 

Section 3.3 in the OECD Manual for Investigation of HPV Chemicals, provides a detailed guidance for the use of SARs in the HPV Chemicals Program (OECD 2002). 

In addition, regulatory initiatives such as the European Union s Registration, Evaluation and Authorization of Chemicals (REACH) program, Canada s Domestic Substances List, and the High Production Volume (HPV) chemical programs in the United States and Europe are key drivers for the... 

HPVIS provides complete and easy access to technical health and environmental effect information on chemicals that are manufactured or imported to US in volumes greater than IMM lbs per year. Information in this database are submitted through HPV Challenge Program. HPVIS allows users to search for summary information, test plans, and new data on high production volume chemicals as they are developed. 

For further details, please consult the description of OECD work on investigation of HPV chemicals prepared by the OECD Secretariat based on the agreements reached in the OECD Existing Chemicals Program up to October 2004 (OECD 2006c). 

In 1998, US-EPA s Administrator invited the Chief Executive Officers of more than 900 chemical companies that account for most of the U.S. manufacture and import of HPV chemicals to participate in the HPV Challenge Program. The program encourages chemical manufacturers to voluntarily test chemicals for which little or no health or environmental effects data were publicly available. 

The High Production Volume (HPV) Challenge Program provides extensive data on chemicals manufactured in or imported to the United States in amounts of at least... 

A9.6.4.4 The U.S. EPA has recently posted a draft document on its website Development of Chemical Categories in the HPV Challenge Program, that proposes the use of chemical categories to voluntarily compile a Screening Information Data Set (SIDS) on all chemicals on the US HPV list. .. [to provide] basic screening data needed for an initial assessment of the physicochemical properties, environmental fate, and human and environmental effects of chemicals (US EPA, 1999). This list consists of ...about 2,800 HPV chemicals which were reported for the Toxic Substances Control Act s 1990 Inventory Update Rule (lUR) . 

US EPA (1999) Development of Chemical Categories in the HPV Challenge Program, http //www.epa.gov/chemrtk/categuid.htm... 

The current OECD HPV chemicals list includes 4853 substances (OECD 2004). The status of each chemical in the process may be monitored via the OECD s publicly available HPV database . The OECD s program enables a member country to sponsor the HPV chemicals produced by industries within its borders and, in turn, to benefit through data sharing from the sponsorship of other countries. This process eliminates duplicative testing. 

United States Environmental Protection Agency. Office of Pesticides and Toxic Substances, Existing Chemicals Assessment Division. Information packet on the OECD Screening Information Data Set (SIDS) Program for high production volume (HPV) chemicals, 1992. 

Chemical Challenge Program, the EU Biocides Program, and the Japan HPV Challenge Program. 

Calculated from Sunset Dates of Chemicals Subject to Final TSCA Section 4 and Related 12(b) Actions, September 1,2009, available at http //www.epa.gov/oppt/chemtest/pubs/sunsettable. html. This total does not include studies performed pursuant to the voluntary initiatives such as the High Production Volume challenge, but does include HPV chemicals that were not voluntarily studied and were later the subject of test rules. See Chapter 10. Voluntary Initiatives, for a discussion of the HPV and other voluntary programs. 

Volume (HPV) chemicals. The plaintiffs contended that the EPA had made de facto B findings when it initiated a voluntary testing program for HPV chemicals. In fact, the EPA conceded that it had found that HPV chemicals were made in substantial quantities and that there was insufficient data and testing was needed to determine the effects of the chemicals. However, the Court found that the EPA had not made findings of substantial release or substantial exposure, and therefore was not required to issue test rules for HPV substances. 

Of the originally proposed 37 chemicals, 11 were being sponsored in the voluntary HPV Challenge Program and SIDS program, 2 were being sponsored in the ICCA HPV Initiative, and 7 were removed from the Ust based on 2002 lUR data because they were imported or manufactured in volumes lower than the one million pound threshold. 71 Fed. Reg. 13708. 13720 (Mar. 16, 2006). 

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