High production volume challenge

EPA (2008b). TSCA inventory reset and inorganic high production volume challenge programs notice of pubhc meeting. Fed Reg 73, 70640—70643. 

Calculated from Sunset Dates of Chemicals Subject to Final TSCA Section 4 and Related 12(b) Actions, September 1,2009, available at http //www.epa.gov/oppt/chemtest/pubs/sunsettable. html. This total does not include studies performed pursuant to the voluntary initiatives such as the High Production Volume challenge, but does include HPV chemicals that were not voluntarily studied and were later the subject of test rules. See Chapter 10. Voluntary Initiatives, for a discussion of the HPV and other voluntary programs. 

See Chapter 10. Voluntary Initiatives for a discussion of the High Production Volume Challenge Program, and see Chapter 2. TSCA s Scope for a discussion of nanomaterials. 

EPA, Office of Pollution Prevention and Toxics, Status and Future Directions of the High Production Volume Challenge Program, EPA 743-R-04-001, 9-10 (Nov. 2004), availabk at http //www.epa.gov/hpv/pubs/general/hpvstatr.htm. 

US EPA. 2004. Status and Future Directions of the High Production Volume Challenge. 

HPVIS provides complete and easy access to technical health and environmental effect information on chemicals that are manufactured or imported to US in volumes greater than IMM lbs per year. Information in this database are submitted through HPV Challenge Program. HPVIS allows users to search for summary information, test plans, and new data on high production volume chemicals as they are developed. 

EPA, High Production Volume (HPV) Challenge Program (http //www.epa.gov/chemrtk/ volchall.htm). 

EDF (2007b) High Hopes, Low Marks. A Final Report Card on the High Production Volume Chemical Challenge. Washington, DC Environmental Defense Fund (EDF). 

High Production Volume (HPV) Challenge is a program defined in 1998 by the EPA for toxicological assessment of substances that are manufactured or imported into the United States. 

EPA (2009a). High production volume (hpv) challenge—guidance documents, http //www.epa.gov/hpv/ pubs/general/guidocs.htm. 

Rosenkranz, H. S., and Cunningham, A. R. (2000). The high production volume chemical challenge program The relevance of the in vivo micronucleus assay. Regul Toxicol Pharmacol 31, 182-189. 

Process design product stewardship and Eastman s voluntary participation in the EPA High-Production Volume Chemical Challenge Program is discussed. There is also a global target to reduce the quantity of raw materials used from 1.28 pounds per pound in 1996 to 1.26 in 2000 (N.B. the figure for 1998 was 1.24 pounds per pound). 

This is known at the High Production Volume (HPV) Challenge. 

It is not uncommon for activists to proceed on both fronts with respect to issues of interest. For example, challenges to the voluntary High Production Volume (HPV) Challenge Program were initiated under both 20 and 21. On December 27, 1999, People for the Ethical Treatment of Animals (PET A) on its own behalf and on behalf of four other organizations, including Physicians Committee for Responsible Medicine, filed a citizens petition... 

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