Domestic Substances List

The higher, long-chain dimers as weH as the tetramer dehydroacetic acid are far more stable and can be handled safely. The alkylketene dimers (AKDs) are shipped to the paper industry in tank tmcks in the form of ready-to-use aqueous emulsions with a total soHds content of 12—25% and a guaranteed shelf life of 30 days, as they have good hydrolytic stabHity. In this form they are not combustible Hquids, and are Hsted in the Canadian Domestic Substances List. 

All eight PMBs are Hsted on the U.S. EPA s TSCA Inventory (May 1, 1994 ed.) and on the European Communities EINECS inventory (June 15, 1990). All but pentamethylbenzene are Hsted on the Canadian Domestic Substances List (DSL) (Apr. 6, 1994). Pentamethylbenzene is Hsted on the Canadian Nondomestic Substances List (NDSL) (Apt. 6, 1994) and as of July 1, 1994 was subject to New Substance Notification if manufactured in or imported into Canada. 

Vinyl chloride is Hsted as "ethene, chloro-" on the Toxic Substances Control Act (TSCA) inventory and on the Canadian Domestic Substances List (DSL). It is Hsted as "chloroethylene" on the European Inventory of Existing Commercial Chemical Substances (EINECS), bearing the identification number 2008 310 (149). 

Poly(vinyl chloride) is Hsted on the TSCA inventory and the Canadian Domestic Substances List (DSL) as ethene, chloro-, homopolymer [9002-86-2]. Because polymers do not appear on the European Community Commercial Chemical Substances listing or EINECS, poly(vinyl chloride) is listed through its monomer, vinyl chloride [75-01-4]. In the United States, poly(vinyl chloride) is an EPA hazardous air pollutant under the Clean Air Act Section 112 (40 CER 61) and is covered under the New Jersey Community Right-to-Know Survey N.J. Environmental Hazardous Substances (EHS) List as "chloroethylene, polymer" with a reporting threshold of 225 kg (500 lb). 

Appendix 1 contains a number of references and links to chemical lists and resources to help identify chemicals of concern. In addition, it maybe useful to review the criteria used to classify substances via EU s Dangerous Substance Directive (67/548/EEC), Environment Canada s Ecological Categorization of Substances on the Domestic Substances List, or Health Canada s Categorization of Substances on the Domestic Substances List when establishing your organization s criteria for selecting chemicals of concern. 

Health Canada Proposal for Priority Setting for Existing Substances on the Domestic Substances List under the Canadian Environmental Protection Act, 1999 Greatest Potential for Human Exposure. This report describes a proposed priority setting process of existing substances in Canada. A stakeholder meeting was convened to discuss the Complex Exposure Model (comET). 

Environment Canada Existing Substances Branch. 2003. Guidance manual for the categorization of organic and inorganic substances on Canada s Domestic Substances List, http //www.ec.gc.ca/substances/ese/eng/psap/guidman2.cfm (accessed July 28, 2005). 

Environment Canada. N.d. Domestic Substances List CEPA Section 71 notices. http //www. ec.gc.ca/substances/ese/eng/dsl/notices avis.cfm (accessed January 8, 2008). 

Robinson P. 2003. Use of (Q)SARs in the categorization of discrete organic substances on Canada s domestic substances list (DSL). 30th annual Aquatic Toxicity Workshop, September 2003, Ottawa, ON, Canada. 

Macdonald, D., Breton, R., Sutcliffe, R., and Walker, J., Uses and limitations of quantitative structure-activity relationships (QS ARs) to categorize substances on the Canadian Domestic Substance List as persistent and/or bioaccumulative, and inherently toxic to non-human organisms, SAR QSAR Environ. Res., 13, 43-55, 2002. 

The Canadian new chemicals program uses two chemical inventories, the Domestic Substances List (DSL) and the Non-Domestic Substances List (NDSL). The DSL includes substances that were, between January 1, 1984, and December 31, 1986, in Canadian commerce, used for manufacturing purposes, or manufactured in or imported into Canada.17 It contains about 23,000 substances. One of the initiatives in the Canadian Environmental Protection Act, 1999 (CEPA, 1999) requires the Minister of the Environment and the Minister of Health to categorize (Section 73, CEPA 1999) and then if necessary, conduct screening assessments (Section 74, CEPA 1999) of substances listed on the DSL to determine whether they are toxic or capable of becoming toxic as defined in the Act. The NDSL is a list of substances not on DSL but in commerce elsewhere in the world.18 The NDSL contains more than 58,000 entries. 

In addition, regulatory initiatives such as the European Union s Registration, Evaluation and Authorization of Chemicals (REACH) program, Canada s Domestic Substances List, and the High Production Volume (HPV) chemical programs in the United States and Europe are key drivers for the... 

The Canadian Environmental Protection Act, 1999 (CEPA 1999) requires the Ministers of the Environment and Health to categorize the substances on the Canadian Domestic Substances List (DSL). The DSL contains 23 000 substances that are subject to categorization (i.e., prioritization). Generally the data selection process involves a search of the scientific literature and databases for quality experimental data for persistence, bioaccumulation potential and inherent toxicity to humans and nonhuman species. If acceptable data are not found, QSARs or other models are used to estimate the persistence, bioaccumulation, and aquatic toxicity of substances based on structure and physical - chemical properties. 

Health Canada, Categorization of Substances on the Domestic Substances List, Available at http //www.hc-sc.gc.ca/hecs-sesc/exsd/categorization dsl.htm (accessed October... 

New chemical substances are all those not on the Domestic Substances List (DSL), which is a list of substances in commerce in Canada at >100 kg a from 1 January 1984 to 31 December 1986. If a new substance is on the Non-Domestic Substances List (NDSL), the information required for the notification is considerably less than for a standard notification. The NDSL, which is the 1985 US TSCA Inventory (as amended) minus the substances on the DSL, attempts to take account of established substances which did not happen to be sold in Canada during the period for inclusion in the DSL. The first DSL [33] and NDSL [34] were both publish in the Canada Gazette on 26 January 1991, and these inventories will be updated and corrected periodically when necessary. Most polymers are represented on the inventories in terms of the starting materials from which they are manufactured, and products of biotechnology will be included subsequently if necessary when their regulatory controls have been finalised. The DSL and NDSL contain confidential sections, which can be searched by Environment Canada if a bona fide intent to manufacture or import is established by submitting specified data. 

Guidelines for the notification and testing of new substances chemicals and polymers pursuant to the new substances notification regulations of the Canadian Environmental Protection Act , 1993, Ministry of Supply and Services, Canada. Canada Gazette Extract, 26 January 1991, Domestic Substances List and Canada Gazette Part /, 5 September, 1992, pp.2735-2737. 

Canada Gazette Extract, 26 January 1991, Non-Domestic Substances List Volumes Land II. 

Common Data Source Approach. Another approach is to use a common source of data for benchmarking a set of chemicals. Examples of potential data sources include Material Safety Data Sheets (MSDSs) from product manufacturers, the Hazardous Substances Data Bank (HSDB), the Integrated Risk Information System (IRIS), the International Uniform Chemical Information Database (lUClID), the High Rroduction Volume Information System (HRVIS), the Organisation for Economic Cooperation and Development (OECD) Screening Information Dataset (SIDS), and the Canadian Domestic Substances list... 

Environment Canada. 2003. Guidance Manual for the Categorization of Organic and Inorganic Substances on Canada s Domestic Substances List Determining Persistence, Bioaccumulation Potential, and Inherent Toxicity to Non-Human Organisms. Ottawa Environment Canada. 

Canadian Provisional Domestic Substance list deflection temperature under load divinylbenzene... 

Canada - Domestic Substance List evaluating environmental and health effects. Also at Provincial level (Ontario)... 

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