Harding-Smith

Harding-Smith T. Learning together an introduction to collaborative learning. New York HarpeiCollins College Publishers 1993. 

Of course, these shortcomings of the Wakao-Smith flux relations induced by the use of equations (8.7) and (8.8) can be removed by replacing these with the corresponding dusty gas model equations, whose validity is not restricted to isobaric systems. However, since the influence of a strongly bidisperse pore size distribution can now be accounted for more simply within the class of smooth field models proposed by Feng and Stewart [49], it is hardly worthwhile pursuing this."... 

Davison CJ, Smith KE, Hutchinson LEF, O Mullane JE, Harding SE, Brookman L, Pe-trak K (1990) J Bioactive Compatible Polym 5 7... 

Morris, G. A. Castile, J. Smith, A. Adams, G.G. Harding, S.E. 2009. Macromolecular conformation of chitosan in dilute solution A new global hydrodynamic approach. Carbohydrate Polymers 76, 616-621. 

Lundin, F. E., J. W. Lloyd, E. M. Smith, V. E. Archer and D. A. Holaday, Mortality of uranium miners in relation to radiation exposure, hard-rock mining and cigarette smoking-1950 through September 1967, Hlth. Phys., 16 571-578 (1969). 

Smith, P.D., Brockway, D.L., Stancil, Jr., F.E. (1987) Effect of hardness, alkalinity and pH on toxicity of pentachlorophenol to senastrum capricomutum (printz). Environ. Toxicol. Chem. 6, 891-990. 

Davies, P.H., J.P. Goettl, Jr., J.R. Sinley, and N.F. Smith. 1976. Acute and chronic toxicity of lead to rainbow trout Salmo gairdneri, in hard and soft water. Water Res. 10 199-206. 

In general, silver concentrations in surface waters of the United States decreased between 1970-74 and 1975-79, although concentrations increased in the north Atlantic, Southeast, and lower Mississippi basins (USPHS 1990). About 30 to 70% of the silver in surface waters may be ascribed to suspended particles (Smith and Carson 1977), depending on water hardness or salinity. For example, sediments added to solutions containing 2 pg Ag/L had 74.9 mg Ag/kg DW sediment after 24 h in freshwater, 14.2 mg/kg DW at 1.5% salinity and 6.9 mg/kg DW at 2.3% salinity (Sanders and Abbe 1987). Riverine transport of silver to the ocean is considerable suspended materials in the Susquehanna River, Pennsylvania — that contained as much as 25 mg silver/kg — resulted in an estimated transport of 4.5 metric tons of silver to the ocean each year (USEPA 1980). The most recent measurements of silver in rivers, lakes, and estuaries using clean techniques show levels of about 0.01 pg/L for pristine, nonpolluted areas and 0.01 to 0.1 pg/L in urban and industrialized areas (Ratte 1999). 

The proportion of C-alkylation increases in the order OTs < Br < I, a sequence which is often associated with the balance of hardness between nucleophile and nucleofuge (Smith and Hanson, 1971). The work of Kurts et al. (1974) indicates that the overall reaction rate of the crown ether-assisted alkylation increases in the order Na+ < K+ < Rb+ < Cs+, which, according to these authors, reflects the increasing distance between cation and anion in the ion pairs. The high reactivity of the tetraphenylarsenate also fits in with this picture. The decrease of the kc/k0 ratio is only small in good cation-solvating solvents such as dimethyl sulfoxide (DMSO). Alkylation of the sodium derivative of [103] with ethyl iodide in DMSO gave kc/kQ = 15.7 addition of... 

Smith and Hanson, 1971). Upon addition of NaBPh4, the free anion was converted into the ion pair, and upon addition of dibenzo-18-crown-6 [11] the ion pair was converted into the free anion. The results (Table 26) show the free anion to be much more reactive than the ion pair towards both methyl iodide and methyl tosylate. The increase in rate is again mainly due to the enhanced reactivity of the hard oxygen centre. The ratio of the rates of alkylation at the two sites of the ambident anion (kN/k0) decreased from about 1.2 for the ion pair to 0.55 and almost zero for the free anion. Increased alkylation of the hard... 

Hardly any French scientists studied abroad. Kirrmann was unusual in his decision to spend a year in Munich in 1930, but he had, after all, been born in German Alsace. John C. Smith notes in his history of Oxford s Dyson Perrins Laboratory, directed by Robert Robinson in the 1920s and 1930s, that there was a great mixture there of ages and nationalities among the twenty or so research students each year but never, until 1947, a French person. 91 This insularity contributed to the closure of the boundaries of the research school associated with Lespieau s laboratory at the Ecole Normale Superieure and to its exclusion from the wider disciplinary history of physical organic chemistry and theoretical chemistry. 

The first edition1 of this book was published approximately 13 years ago. Its primary objective was to present an overview and a "roadmap" of the process of new drug discovery and development, particularly oriented to individuals or companies entering the pharmaceutical field. It was written by one of the authors (Smith), with no contributors, and drawn on Smith s experiences in the industry and field over the course of nearly 40 years. In the second edition, the scope of the first book has been expanded and technical details in the form of hard data have been included. In addition to the editors own commentary and contributions, the major part of the book is the result of contributions of experts in the industry. New chapters on risk assessment, international harmonization of drug development and regulation, dietary supplements, patent law, and entrepreneurial startup of a new pharmaceutical company have been added. Some of the important, basic operational aspects of drug discovery and development (e.g., organizational matters, staff requirements, pilot plant operations, etc.) are not repeated in this book but can be found in the first edition. 

The work of the San Francisco group described in this article has only been possible because of the hard work and insights of Angela Wilks, Justin Torpey, and Yi Liu, and fruitful collaborations with the groups of Tom Poulos, Tom Loehr, Gerd LaMar, and Kevin Smith. The work in San Francisco and the preparation of this review were supported by National Institutes of Health grant DK30297. 

In contrast, through eons of evolution Nature has come up with many biopolymers that can combine important mechanical properties including strength, toughness, and elasticity. For example, sUks (Oroudjev et al. 2002), cell adhesion proteins (Law et al. 2003), and connective proteins existing in both soft and hard tissues such as muscle (Kellermayer et al. 1997 Rief, Gautel, et al. 1997 Marszalek et al. 1999 Li et al. 2000), seasheUs (Smith et al. 1999), and bone (Thompson et al. 2001)... 

L. Neil Smith, science fiction writer, libertarian, and gun rights activist. Smith has written many pro-gun articles and opinion pieces that feature a crisp, hard-hitting style. His fiction emphasizes the moral dimensions of arms bearing and self-defense For example, in The Probability Broach, virtually all people (even children) carry weapons, viewing it as a symbol of autonomy, responsibility, and moral health. 

The major problem with LIF measurements in the past has been what might be called the atmospheric uncertainty principle i.e., in the act of carrying out the measurement, the system is perturbed and artifact formation of OH can occur (e.g., see Smith and Crosley, 1990 and Hard et al., 1992b). This is primarily due to the photolysis of 03 to generate O( D), which in the presence of water vapor forms OH ... 

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