Gastritis, alcohol

Dietary factors such as coffee, tea, cola, beer, and a highly-spiced diet may cause dyspepsia, but they have not been shown to independently increase PUD risk. Although caffeine increases gastric acid secretion and alcohol ingestion causes acute gastritis, there is inconclusive evidence to confirm that either of these substances are independent risk factors for peptic ulcers. 

Many other organs are also sensitive to alcohol abuse. The stomach may develop chronic or acute gastritis, and ulcers are prevented from healing. Pancreatitis... 

Individuals with chronic alcoholism are prone to gastritis and have increased susceptibility to blood and plasma protein loss during drinking, which may contribute to anemia and protein malnutrition. Alcohol also reversibly injures the small intestine, leading to diarrhea, weight loss, and multiple vitamin deficiencies. 

Alcohol consumption causes peripheral vasodilatation the person feels warm, body heat is slowly lost, and an overdose can cause rapid hypothermia. An acute dose of 3 to 4 units will increase blood pressure. It will cause irritation to gastric mucosae followed by erosion that heals after 3 to 4 weeks. At least 60% of chronic gastritis is reported with chronic alcoholics. Alcohol intake also affects sexual function. William Shakespeare wrote that alcohol provides the desire but takes away the performance. Alcohol can be source of energy but cannot be used as food. 

The gastritis and chronic pancreatitis associated with chronic alcoholism may result in a reduction of the amount of vitamin B12 absorbed but this has not been found to result in a clinical deficiency (M4). Alcohol can also cause damage to the ileum. Lindenbaum and Lieber gave alcohol to human volunteers for periods of 13—37 days and found that absorption of the vitamin was impaired in six of eight volunteers and this was not corrected by the addition of intrinsic factor or pancreatin (L10,L11). Biopsy of the ileum showed ultra-structural evidence of mitochondrial damage (Rll). It has been shown previously that folate deficiency may result in a reduction in the serum vitamin B12 level (H16) and the low serum vitamin B12 levels found in some alcoholics is probably secondary to folate depletion, which is common in this condition (L12). How folate is able to influence the serum vitamin B12 level is not clear. 

In addition, most alcoholics suffer from a poor diet as they get most of their calories from the alcohol (see above), and the gastritis and ulcers they may suffer reduces their appetite for food. They will therefore probably have a low blood level of glucose. Pregnant women who drink significant amounts of alcohol produce smaller babies, the so-called foetal alcohol syndrome . 

Gastric mucosa. Injury occurs because alcohol allows back diffusion of acid from the gastric lumen into the mucosa. After an acute binge the mucosa shows erosions and also petechial haemorrhages (recovery may take 3 weeks) and up to 60% of chronic alcoholics show chronic gastritis. 

Isopropyl alcohol is about twice as toxic as ethanol and should therefore not be administered orally isopropyl alcohol also has an unpleasant taste. Symptoms of isopropyl alcohol toxicity are similar to those for ethanol except that isopropyl alcohol has no initial euphoric action and gastritis and vomiting are more prominent see Alcohol. Delta osmolality may be useful as rapid screen test to identify patients at risk of complications from ingestion of isopropyl alcohol. The lethal oral dose is estimated to be about 120-250 mL although toxic symptoms may be produced by 20 mL. 

When pancreatin is administered to patients in some galenic formulation, it mixes with the food mass and performs some digestion in the stomach. However, most enzymic activities will be destroyed before reaching the duodenum [76]. Only therapeutic results can be expected in patients where the postprandial pH remains relatively high as a consequence of, for example, alcoholic gastritis or concomitant medication with inhibitors of gastric acid secretion. 

Chronic alcoholism produces pathologic changes such as chronic gastritis, cirrhosis of the Uver, alcoholic cardiomyopathy, Korsakoff s syndrome, bloatedness, flabby muscles, fine tremors, impaired physical capacity and stamina, diminished will power, and impaired memory. Accompanying malnutrition may contribute to alcohol-induced tissue injury. 

Ethylene glycol is the primary ingredient (up to 95%) in antifreeze. It is sometimes intentionally consumed as an alcohol substitute by alcoholics and is tempting to children because of its sweet taste. Intoxication by ethylene glycol itself causes inebriation and mild gastritis in addition, its metabolic products cause metabolic acidosis, renal failure, and death. Other glycols may also produce toxicity (Table 11-24). 

C. Isopropyl alcohol is irritating to the gastrointestinal tract and commonly causes gastritis. 

Precautions Some studies have indicated that small quantities (four ounces per day) have been found to be beneficial in lowering cholesterol. Large quantities over extended periods can lead to alcoholism, liver damage, numbness of the extremities, brain damage, gastritis, and heart muscle damage. Pregnant women should avoid alcohol entirely because of the disastrous effects on the unborn. 

TOO- 500 alcoholic gastritis old stomachal ulcer old case of hypersecretion, o- 100 chronic gastritis. Cancer. 

Iron deficiency is commonly caused by insufficient dietary intake, excessive menstrual flow, multiple births, and gastrointestinal bleeding (occult or patent) due to medications (aspirin, steroids), hiatal hernia, peptic ulcers, gastritis associated with alcoholism, anemia of chronic disease, geophagia, and tumors. After these patients are carefully diagnosed, iron supplementation is administered using oral ferrous sulfate or by intravenous therapy with an iron-dextran complex (Imferon) [28,29]. 

---