Memory impairments

Membrane transport Memory Memory banks Memory device Memory-enhancing drug Memory-impairment Memory protection Memory storage device Memory systems Menadione... 

ChEI treatments have been expanded also to include other dementias and CNS disorders, e.g. delirium, traumatic brain injuries and memory impairments, as well as myasthenia gravis, glaucoma and parasite infections. 

Because of memory impairment and alterations in tilinking in some patients witii parkinsonism, a history obtained from tiie patient may be unreliable When necessary, tiie nurse obtains tiie health history from a family member. Important data to include is information regarding tiie symptoms of tiie disorder, tiie length of... 

Myxedema is a severe hypothyroidism manifested by lethargy, apathy, memory impairment, emotional changes, slow speech, deep coarse voice, thick dry skin, cold intolerance, slow pulse, constipation, weight gain, and absence of menses. 

Bolla KI, McCann UD, Ricaurte GA Memory impairment in abstinent MDMA ( ecstasy ) users. Neurology 51 1532—1537, 1998 Borgen L, Lane E, Lai A Xyrem (sodium oxybate) a study of dose proportionality in healthy human subjects. J Clin Pharmacol 40 1053, 2000 Borgen LA, Okerholm R, Morrison D, et al The influence of gender and food on the pharmacokinetics of sodium oxybate oral solution in healthy subjects. J Clin Pharmacol 43 59-65, 2003... 

Acute clinical signs of neurotoxicity, manifested by hyperexcitability, dyspnea, decreased respiration, tremors, and convulsions, were identified in the available literature as effects caused by high doses of endosulfan. Exposure to high levels of endosulfan in humans may possibly be associated with permanent brain damage as manifested by cognitive and emotional deterioration, memory impairment, and... 

Everybody suffers some intellectual and memory impairment with age. If it becomes very marked or occurs earlier in life (40+) it is known as dementia. Although it may be caused by alcoholism, cardiovascular disease such as multiple infarcts, and is often seen in the later stages of Parkinsonism, the most common cause is a neurodegenerative one, namely, Alzheimer s disease (AzD). In fact this is the primary and sole cause in over half the cases of dementia and is a contributory cause in a further quarter and the younger the patient, the more likely is the dementia to be of the Alzheimer type. 

Yamada, K, Tanaka, T, Mamiya, T, Shiotani, T, Kameyama, T and Nabeshima, T (1999) Improvement by nefiracetam of /i-amyloid—(1-42)—induced learning and memory impairments in rats. Brit. J. Pharmacol. 126 235-244. 

Electroconvulsive therapy (ECT) is a highly efficacious treatment for MDD. The response rate is about 80% to 90% and even exceeds 50% for patients who have failed pharmacotherapy.16,17 ECT may be particularly beneficial for MDD that is complicated by psychotic features, severe suicidality, refusal to eat, pregnancy, or contraindication/non-response to pharmacotherapy.16,17 ECT is typically a very safe treatment alternative, but various cautions do exist, and the chief side effects are confusion and memory impairment.16... 

Dementia is the loss of function in multiple cognitive domains that occurs over a longer period of time, usually months to years. Diagnostic features include memory impairment and at least one of the following aphasia (deterioration of speech), apraxia (impaired ability to execute motor activities despite intact motor abilities, sensory function, and comprehension of the required task), agnosia (failure to recognize or identify objects despite intact sensory function), or disturbances in executive functioning.1... 

Laszy J, Laszlovszky I, Gyertyan I. Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats. Psychopharmacology (Berl) 2005 179 567-575. 

Bolla KJ, McCann UD and Ricaurte GA (1998). Memory impairment in abstinent MDMA (Ecstasy) users. Neurology, 51, 1532-1537. 

Veng LM, Mesches MH and Browning MD (2003). Age-related working memory impairment is correlated with increases in the L-type calcium channel protein alD (Cavl.3) in area CA1 of the hippocampus and both are ameliorated by chronic nimodipine treatment. Molecular Brain Research, 110, 193-202. 

Zakzanis KK and Young DA (2001). Memory impairment in abstinent MDMA ( Ecstasy ) users A longitudinal investigation. Neurology, 56, 966-969. 

Lanahan A et al. Selective alteration of long-term potentiation-induced transcriptional response in hippocampus of aged, memory-impaired rats. J Neurosci 1997 17 2875-2885. 

While the conditional gene knockout experiments are supportive of a role for the NMDA receptors in memory, they are less than fully conclusive in linking the synaptic coincidence-detection feature of the NMDA receptor to memory formation. Like all loss-of-function studies, CA1-specific gene-knockout experiments could, in theory, produce memory impairment via a mechanism independent of the coincidence-detection function of the NMDA receptor. For example, one may argue that the physical absence of the NMDA receptor channels may cause subtle structural reconfiguration at the synapse, thereby altering normal synaptic transmission. Therefore, the memory impairment in CA1-specific NR1 knockout mice does not allow a firm conclusion that the coincidence-detection function of NMDA receptors controls learning and memory processes at the cellular level. 

Zola-Morgan, S, Squire, L. R. and Amaral, D. Human amnesia and the medial temporal region Enduring memory impairment following a bilateral lesion limited to the CA1 field of the hippocampus. /. Neuroscience 6 2950-2967, 1986. 

Up to 40% of patients complain of headache, memory impairment, confusion, poor concentration, and impaired motor performance. A fine hand tremor may occur in up to 50% of patients. Hand tremor may be treated with propranolol 20 to 120 mg/day. 

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