Follicles

Hair follicles Hair preparation Hair preparations... 

Female sexual development and behaviour in mammals occurs by default and requires no ovarian secretion, and it is only in genetic males that the testis can secrete hormones which destroy this female pattern and superimpose that of the male. Sexual differentiation is not so well defined in fish, and larval exposure to both synthetic estrogens and androgens is widely used in aquaculture to produce monosex cultures. Endocrine disruption of sexual differentiation in fish may therefore reflect both the complexity and diversity of such processes between different species. Some care is required in use of the terms hermaphrodite and sex-reversal since a true hermaphrodite has both functional testes and ovaries and a sex-reversed fish is fully functional as its final sex—both produce the appropriate viable gametes. Such functional sex-reversal is not possible in mammals, but in some species of fish it is the normal developmental pattern. In most of the cases of hermaphroditism or sex-reversal reported in the non-scientific press, there is evidence only for a few ovarian follicles within a functional testis. This may be considered as feminisation or a form of intersex, and is very clearly endocrine disruption, but it is certainly neither sex-reversal nor hermaphroditism. In some cases the terms have even been used to infer induction of a single female characteristic such as production of yolk-protein by males. 

Follicle Stimulating Hormone (FSH, foilitropin) [9002-68-0] Mr 36,000. Purified by Sephadex GlOO gel filtration followed by carboxymethyl-cellulose with NH4OAC pH 5.5. The latter separates luteinising hormone from FSH. Solubility in H2O is 0.5%. It has an isoelectric point of 4.5. A soln of Img in saline (lOOmL) can be kept at 60° for 0.5h. Activity is retained in a soln at pH 7-8 for 0.5h at 75°. The activity of a 50% aq EtOH soln is destroyed at 60° in 15 min. [Bloomfield et al. Biochim Biophys Acta 533 371 1978 Hartree Biochem J100 754 1966 Pierce and Parsons Ann Rev Biochem 50 465 1981.]... 

Balg. m. skin bellows husk, pod, shell chaff (Med.) cyst follicle, -auszug, m. bellows extension, -frucbt, /. (Bot.) follicle, -ge-schwulst, n. (Med.) cystic tumor. 

Haar-balg. m. hair follicle. -balgdrUse. /. sebaceous gland. -beize, /. depilatory, -bleiche, /. hair bleaching, -blutgefass, n. (Anat.) capillary, -draht, m. extremely thin wire, capillary wire, -driise, /. sebaceous gland. 

Perhaps the most common and well-publicized use of DNA fingerprinting is that carried out by crime laboratories to link suspects to biological evidence— blood, hair follicles, skin, or semen—found at a crime scene. Thousands of court cases have now been decided based on DNA evidence. 

Thyroid stim. hormone Follicle-stim. hormone Luteinizing hormone... 

Chorionic gonadotropin (CG) is produced in the placenta. Together- with the pituitary hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), it constitutes the glycoprotein family of gonadotropins. The actions of CG are mediated by the LH receptor, both belonging to the superfamily of G-protein Coupled Receptors. 

In the skin, ENaC is expressed in keratinocytes of the epidermis and in hair follicles. It could play a role in terminal differentiation by modulating keratinocyte calcium signaling. The skin expresses MR, GR, and 11 3HSD2, but the role of aldosterone and glucocorticoids on ENaC activity and keratinocyte differentiation is not yet understood. 

Induction of ovulation, stimulation of multiple follicle development... 

---