Exogenous follicle-stimulating hormone ovarian

In order to improve the predictive value of basal FSH, Fanchin et al. (F2, Ol) have introduced the exogenous follicle-stimulating hormone ovarian reserve test (EFORT). On cycle day 3, two menstrual cycles before IVF treatment, basal FSH as well as estradiol concentrations are determined in serum, and 300IU of FSH are administered i.m. After 24 h, estradiol levels are determined again. The predictive value of basal FSH <12 U/liter and a rise in estradiol >30 pg/ml is more predictive of adequate ovarian response than basal FSH alone. 

F2. Fanchin, R., De Ziegler, D., Olivennes, F., Taieb, J., Dzik, A., and Frydman, R., Exogenous follicle stimulating hormone ovarian reserve test (EFORT) A simple and reliable screening test for detecting poor responders in in-vitro fertilization. Hum. Reprod. 9, 1607-1611 (1994). 

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