Prostate cancer epidermal growth factor receptor

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Dorai, T., Gehani, N., and Katz, A., Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein, Mol. Urol., 4, 1, 2000. 

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Mimeault M, Pommery N, Wattez N, Bailly C, Henichart JP (2003) Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines implication of epidermal growth factor receptor down-regulation and ceramide production. Prostate 56 1-12... 

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Overexpression of FASN in tumor cells is induced at the transcriptional level by receptor tyrosine kinase (RTK)-stimulation of Ras and Akt (Fig. 7.2B). Keratinocyte growth factor (KGF) can induce the Akt- and cJun N-terminal kinase (JNK)-dependent expression of FASN in pulmonary cancer cells (Chang et ah, 2005). Epidermal growth factor (EGF) has also been shown to increase FASN in prostate cancer cells (Swinnen et ah, 2000a). 

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