Prostate carcinogenesis

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De Marzo, A, N Yasutomo, and WG Nelson. 2007. Inflammation, atrophy, and prostate carcinogenesis. Urol Oncol 25 398-400. 

Gupta S, Flastak K, Ahmad N, Lewin JS, Mukhtar H. 2001. Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc Natl Acad Sci USA 98 10350-10355. 

Pathak, S.K. et al., Oxidative stress and cyclooxygenase activity in prostate carcinogenesis, targets for chemopreventive strategies, Eur. J. Cancer, 41(1), 61, 2005. 

W3. Wang, Y. Z., and Wong, Y. C., Sex hormone-induced prostatic carcinogenesis in die noble rat die role of insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in the development of prostate cancer. Prostate 35, 165—177 (1998). 

Cui L, Mori T, Takahashi S, et al. (1998) Slight promotion effects of intermittent administration of testosterone propionate and/or diethylstilbestrol on 3,3 -dimethyl-4-ami-nobiphenyl-initiated rat prostate carcinogenesis. Cancer Letters 9 195-199. 

Ho, S.M. (2004) Estrogens and antiestrogens key mediators of prostate carcinogenesis and new therapeutic candidates. Journal of Cellular Biochemistry, 91, 491-503. 

Yao V, Parwani A, Maier C, et al. Moderate expression of prostate-specific membrane antigen, a tissue differentiation antigen and folate hydrolase, facilitates prostate carcinogenesis. Cancer Res.2008 68 9070. 

De Marzo AM, DeWeese TL, Platz EA, et al. Pathological and molecular mechanisms of prostate carcinogenesis implications for diagnosis, detection, prevention, and treatment. J Cell Bio-chem. 2004 91 459. 

Gurel B, Iwata T, Koh CM, et al. Nuclear MYC protein overexpression is an early alteration in htrman prostate carcinogenesis. Mod Pathol. 2008 21 1156. 

Tang, D., Liu, J.J., Rundle, A., Neslund-Dudas, C., Savera, A.T., Bock, C.H., Nock, N.L., Yang,).)., and Rybidd, B.A. (2007) Grilled meat consumption and PhIP-DNA adducts in prostate carcinogenesis. Cancer Epidemiol. Biomarkers Prev., 16,... 

Suppression of Prostate Carcinogenesis by Tea Polyphenols through Inhibiting Microsomal Aromatase and 5a-Reductase... 

Prostate cancer is the most common cancer in males living in developed countries and the second leading cause of cancer death. Curcumin has been reported to have anti-prostate cancer activity in vitro and in vivo [50-52]. Although mechanisms of action have been postulated [53], they are not yet fully understood. The androgen receptor (AR) plays an important role in prostate carcinogenesis therefore, anti-AR reagents such as hydroxyflutamide are widely used for the treatment of prostate cancer. 

Shuk-Mei H, Tang W, Frausto J, Prins G. Developmental exposure to Estradiol and Bisphenol A increases susceptibility to prostate carcinogenesis and epigeneticaUy regulates phosphodiesterase type 4 variant 4. Cancer Res 2006 66 (11) 5624—5632. 

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