Dermatitis arnica

For external use only causes cardiac toxicity if ingested stop using if arnica liniment causes dermatitis... 

REIDER, N., KOMERICKI, P., HAUSEN, B.M., FRITSCH, P ABERER, W., The seamy side of natural medicines Contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.)., Contact Dermatitis, 2001,45,269-272. 

Exposure to Asteraceous plants may also result in the development of contact dermatitis. One Serbian study has indicated that it is not unusual to detect sensitization to chamomile (Chamomilla recutita), arnica (Arnica montana), tansy (Tanacetum vulgare), and feverfew (Tanacetum parthenium) (Jovanovic et al., 2004). Contact dermatitis, along with asthma and rhinitis, may also accompany occupational exposure to chamomile (Rudzki et al., 2003) and contact dermatitis to feverfew (Hausen, 1981). Similarly, chamomile in cosmetic products can also be a cause of dermatitis (Paulsen, 2002 Rycroft, 2003). Because chamomile-containing products, particularly in shampoos and other OTC products, are so widespread, the linkage to these types of adverse events are likely underreported. Also, use of royal jelly, a thick mixture of honey, pollen, and their allergens, has been associated with several cases of bronchospasm, and topical application of concentrated forms of bee pollen (propalis) to contact dermatitis (Perharic, 1993). Milk thistle has also been known to cause urticaria (De Smet, 2004). 

E.3 ContactedlerpfensThc sesquiterpene lactones of the Asteraceae, e.g. chrysanthemums, asters and daisies, are well-known causes of contact allergic dermatitis. Patients with such allergies should avoid (and should be advised to avoid) herbs such as Artemisia (Mugwort), Chamomile, Yarrow (Achillea). Feverfew, Echinacea-inA Arnica because of cross-sensitisation. 

Allergic contact dermatitis to arnica has been reported and is associated in some cases with sensitivity to other species of plants in the Asteraceae and Lauraceae families (Brinkhaus et al. 2006 Hausen 1980,1985,1992,1996 Hausen and Schulz... 

Hausen, B.M. 1978. Identification of the allergens of Arnica mon-tana L. Contact Dermat. 4(5) 308. 

Hormann, H., and H. Korting. 1995. Allergic acute contact dermatitis due to arnica tincture self-medication. Phytomedicine 3 315-317. 

Machet, L., L. VaUlant, A. CaUens, et al. 1993. AUergic contact dermatitis from sunflower (Helianthus annuus) with cross-sensitivity to arnica. Contact Dermat. 28(3) 184-185. 

Pirker, C., T. Moslinger, D.Y. Koller, M. Gotz, and R. Jarisch. 1992. Cross-reactivity with Tagetes in Arnica contact eczema. Contact Dermat. 26(4) 217-219. 

Rudzki, E., and Z. Grz)rwa. 1977. Dermatitis from Arnica rrumtana. Contact Dermat. 3 281-282. 

Schwarzkopf, S., P.L. BigUardi, and R.G. Panizzon 2006. Allergic contact dermatitis from Arnica. Rev. Med. Suisse 2(91) 2884-2885. 

Ci5H g04, Mr 262.31, cryst., mp, 168 °C, [ajp -102° (acetone), soluble in alcohol, chloroform, poorly soluble in water. A toxic sesquiterpene lactone that induces sneezing from Helenium and Arnica species such as, e.g., Helenium autumnale and Arnica mon-tana [LD50 (mouse p.o.) 150 mg/kg]. After intoxication, the symptoms are nasal irritation, vomiting, diarrhea, vertigo, palpitation, respiratory impairment, and finally collapse with a weak, very rapid pulse. In the past deaths have been reported after consumption of Arnica preparations. Contact with the skin leads to dermatitis. 

Hausen BM (1978) Indentification of the allergens of Arnica montana L. Contact Dermatitis 4 308... 

Definition Plant material from dried flowerheads, roots, or rhizomes of Arnica montana Properties Herbaceous sweet odor, si. bitter flavor Toxicology Poison by inh. and ing. mod. irritant allergen may cause contact dermatitis, Gl symptoms, nervous disturbances, and collapse... 

Sunflower (Helianthus annuus) causes allergic contact dermatitis in agricultural workers engaged in growing the plant for commercial purposes [152, 153, 154]. This sensitivity may produce a cross-reaction to Arnica [155]. The eruption commonly involves exposed sites and the hands. The SQTL antigen is located in fragile multicellular, capitated glandular trichomes [156]. 

Treatment of occupational illness may cause sensitization. With the use of botanical material for its pharmacologic properties, one may see patients who break out to plants in occupations where there should not be an opportunity for exposure. For example, reactions to Arnica montanUy Matricaria chamomillay Echinacea angustifoliay Hamamelis spp.. Calendula officinalis [434] and Melaleuca alternifolia are reported in alternative treatments . The latter is said to cross-react with colophony and contains eucalyptol, which caused systemic contact dermatitis in one patient [435, 436]. 

Hausen BM, Spring O (1989) Sunflower allergy. On the constituents of the trichomes of Helianthus annuus L. (Compositae). Contact Dermatitis 20 326-334 Hausen BM, Herrmann HD, Willuhn G (1978) The sensitizing capacity of Compositae plants. 1. Occupational contact dermatitis from Arnica longifolia Eaton. Contact Dermatitis 4 3-10... 

Hermann, H. and Korting, H. 1995, Allergic acute dermatitis due to Arnica tincture self-medication . Phytomedicine 4 315-317. 

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