Dendritic cell lung cells

Expression (Human) Tissues Leukocytes, thymus, spleen, liver, ovary Cells PBLs, neutrophils,T-cells, dendritic cells, mast cells, eosinophils, macrophages, leukocytes Tissues spleen, small intestine, placenta, lung smooth muscle, Cells bronchial smooth muscle, CD34+ hemapoietic progenitor cells, monocytes, macrophages, mast cells, eosinophils, neutrophils, PBLs, human umbilical vein endothelial cells Tissues, heart, skeletal muscle, spleen, brain, lymp node, adrenal medulla, lung, human pumonary/ saphenous vein Cells monocytes, macrophages, mast cells, eosinophils, cardiac muscle, coronary artery, PBLs... 

Circulating dendritic cells Langerhans cells Interdigitating dendritic cells Interstitial dendritic cells Blood, lymph Skin, mucous membrane Secondary lymphoid tissue (with T cells), thymus Gastrointestinal tract, heart, liver, lungs, kidney... 

Xia, W.J., Schneeberger, E.E., McCarthy, K. and Kradin, R.L. (1991). Accessory cells of the lung. II. Ia+ pulmonary dendritic cells display cell surface antigen heterogeneity. Am. J. Respir. Cell. Mol. Biol. 5, 276-283. 

Colasante A, Castrilli G, Aiello FB, et al. Role of cytokines in the distribution of dendritic cells/Langerhans cell lineage in human primary carcinomas of the lung. Hum Pathol. 1995 26 866-872. 

De Heer HJ. Hammad H. Soullie T. Hijdra D, Vos N, Willart MA. Hoogsteden HC. Lambrecht BN Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med 2004 200 89-98. 

Spiegel DE. Tucker J. Battaile JT. Alevy Y, Yan L. Agapov E. Kim EY. Holtzman MJ Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia. J Exp Med 2007 204 2759-2769. 37... 

Key Words Allergy asthma lung pulmonary T cell mast cell eosinophil inflammation dendritic cell IgE B cell. 

Huh JC, Strickland DH, Jahnsen FL, Turner DJ, Thomas JA, Napoli S, Tobagus I, Stumbles PA, Sly PD, Holt PG Bidirectional interactions between antigen-bearing respiratory tract dendritic cells (DCs) and T cells precede the late phase reaction in experimental asthma DC activation occurs in the airway mucosa but not in the lung parenchyma. J Exp Med 2003 198 19-30. 

Lung Dendritic Cells Targets for Therapy in Allergic Disease... 

Function of Lung Dendritic Cells Induction of Tolerance in Steady-State and Bridging Innate and Adaptive Immunity... 

De Heer HJ. Hammad H. Kool M. Lambrecht BN Dendritic cell subsets and immune regulation in the lung. Semin Immunol 2005 17 295-303. 

Dahl ME, Dabbagh K, Liggitt D, Kim S, Lewis DB Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells. Nat Immunol 2004 5 337-343. 

Beaty SR, Rose CE Jr, Sung SS Diverse and potent chemokine production by lung GDI lb dendritic cells in homeostasis and in allergic lung inflammation. J Immunol 2007 178 1882-1895. 

Idzko M, Hammad H, van Nimwegen M, Kool M, Muller T. Soullie T, Willart MA, Hijdra D, Hoogsteden HC, Lambrecht BN Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function. J Clin Invest 2006 116 2935-2944. 

Hammad H, Kool M, Soullie T, Narumiya S. Trottein F. Hoogsteden HC, Lambrecht BN Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J Exp Med 2007 204 357-367. 

Dendritic cells are very important APCs along with mononuclear phagocytes. They are distributed in small quantities in various tissues that come in contact with the external environment including the skin, inner lining of the nose, lungs, stomach and intestine. The blood contains immature dendritic cells. After activation, dendritic cells migrate to the lymphoid tissue to initiate an acquired response following their interaction with lymphoid cells, B and T cells. There are two most common types... 

Lung Macrophages and Dendritic Cells in Health and Disease, edited by M. F. Lipscomb and S. W. Russell... 

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