Cyclohexyl aliphatic acids

The process can be still more simplified. It is not always necessary to use a pre-formed Schiff s base. Often it is sufficient to bring the carbonyl compound and the amine together in an inert solvent and to add the peracid to the mixture later, - In this way oxaziranes can be obtained in good yield even if the Schiff s base is unknown or can only be obtained in poor yield. For example, formaldehyde gives with aliphatic amines usually only trimers of the Schiff s bases (4). On the other hand, the synthesis of 2-cyclohexyl-oxazirane (5) from cyclohexylamine, formaldehyde, and peracetic acid proceeded in 66%... 

Production of considerable amounts of cyclohexanol and cyclohexanone as well as benzaldehyde and benzoic acid in the oxidation of benzyl cyclohexyl ether shows the primary radical to be CgHjCHOCeHjj. Abstraction from aliphatic C-H bonds cannot occur in the case of diphenyl ether which is oxidised rapidly, and removal of a 7t-electron is likely. 

We have shown that a number of aliphatic ethers, containing steric-ally accessible p-hydrogen atoms, are cleaved in good yield when the tetrahalogenoanthranilic acids are diazotised in ethers 128,59). Diethyl ether is cleaved to the tetrahalogenophenetole (90) and methyl-cyclohexyl ether affords the tetrahalogenoanisole. In this latter reaction we were able to detect cyclohexene and therefore a plausible, but as yet unproved, mechanism is as shown. 

The progressive introduction of methyl groups into the pendant phenyl ring of Cl Acid Blue 25 (6.30 R = H) leads to an increase in dye uptake and to improved wet fastness properties on wool [12]. Steric crowding in the case of Cl Acid Blue 129 (6.33) reduces the conjugation of the 4-substituent with the remainder of the system and results in a reddish blue hue. The aliphatic cyclohexyl ring in Cl Acid Blue 62 (6.31) has a similar effect on the hue. 

The reactions of NP with different aliphatic amines (ethyl-, n-propyl-, n-butyl-, cyclohexyl-, and benzylamines) and amino acids have... 

Whereas a number of 5-aryl thiatriazoles have been reported, the only previously known true aliphatic and alicyclic representatives were 5-tert-butyl31 and cyclohexyl thiatriazole.32 These are unstable oils that decompose at 0° with nitrogen evolution and formation of sulfur. They are prepared from the corresponding thioacylhydrazides and nitrous acid, but the method is not generally applicable because of difficulties in obtaining the required aliphatic thioacylhydrazides.1 Wijers et o/.17 have found that aliphatic thiatriazoles can be prepared from 1-acetylthio-l-alkynes. Thus a substance believed to be 5-pentylthiatriazole was isolated from the reaction between 1-acetylthio-l-hexyne and ammonium azide. It is an oil that solidifies at about —16° and could not be analyzed because of its explosive character and poor stability at room temperature. Its formation is explained by the following scheme [Eq. 

Among the features of Volume 41 is the smallest-scale synthesis yet published in Organic Syntheses, namely, the preparation of 0.0005 mole of cholestanyl methyl ether by a generally useful methylation procedure that employs diazomethane and fluoboric acid (p. 9). Two preparations of isocyanides by dehydration of formamides are included. One of these, illustrated by cyclohexyl isocyanide (p. 13), is most suitable for aliphatic isocyanides while the other, illustrated by o-tolyl isocyanide (p. 101), is most suitable for aromatic isocyanides. 

CYCLOHEXYL ALCOHOL (108-93-0) Combustible liquid (flash point 154°F/ 68°C). Contact with oxidizers can cause fire and explosions. Violent reaction with chromium trioxide, nitric acid. Incompatible with strong acids, caustics, aliphatic amines, isocyanates. Attacks some plastics, rubber, or coatings. 

CYCLOHEXYL-4,6-DINITROPHENOL (131-89-5) Combustible solid (flash point unknown). Contact with alkaline materials or UV light may cause decomposition. Reacts with strong oxidizers, with a risk of tire or explosions. Incompatible with sulfuric acid, nitric acid, caustics, aliphatic amines, isocyanates. 

The reaction of a diepoxide with a carboxylic acid-terminated polymer will, therefore, result in a coupling of two chains. This method has been proposed in a patent as early as 1971. In the late 1990s, a comparative study of chain extension of PET by means of several commercial diepoxides has been reported. The reactions were carried out at 270 °C for different periods of time. The diepoxides 1 and 2 of Figure 1, comprising aliphatic cyclohexyl moieties, gave chain extension reaction as evidenced by the increase in intrinsic viscosities and substantial decrease of carboxyl content of the end products. With the diglycidyl ether types (3, 4, and 5), however, decreased viscosity values, increased carboxyl content, and lower melting points were observed. 

A new facile method for the rapid synthesis of aliphatic polyamides and polyimides was developed by using a domestic microwave oven to facilitate the polycondensation of both w-amino acids and nylon salts as well as of the salt monomers composed of aliphatic diamines and pyromellitic acid or its diethyl ester in the presence of a small amount of a polar organic medium. Suitable organic media for the polyamide synthesis were tetramethylene sulfone, amide-type solvents such as A -cyclohexyl-2-pyrrolidone (CHP) and 13-dimethyl-2-imidazolidone (DMI), and phenolic solvents like m-cresol and c)-chlorophenol, and for the polyimide synthesis amide-type solvents such as A-methyl-2-pyrrolidone, CHP, and DMI. In the case of the polyamide synthesis, the polycondensation was almost complete within 5 min, producing a series of polyamides with inherent viscosities around 0.5 dL/g, whereas the polyimides having the viscosity values above 0.5 dL/g were obtained quite rapidly by the microwave-assisted polycondensation for only 2 min. 

Abstract This review covers the recent recyclable protocols for the C-N bond forming reactions between aromatic, heterocyclic and aliphatic amines such as imidazoles, benzimidazoles, benzylamines, piperidine, pyrrole, imides, anilines, hexyl, cyclohexyl amines, and amides as coupling partners with aryl iodides, bromides, chlorides, and arylboronic acids employing copper-mediated systems. The physical properties and characterization of the catalysts and their use in organic synthesis will be outlined. Most importantly, these recyclable versions developed by many groups in the recent years are potential candidates for commercial exploitation. The effect of additives, solvents, temperature, base, the nature of aryl halides on reactivity, and recycle studies of the heterogeneous catalysts are included in this... 

It is clear from Table 32 that A-arylation proceeds very effectively and afforded the corresponding A-arylated products in good to excellent yields under very mild conditions. No spectacular electronic effects were observed in N-arylatimi of aniline only a slight decrease in the reactirai rate was noted with the 3-nitrophenylboronic acid. Next we examined the N-arylation of various primary amines such as aliphatic, cyclohexyl and heterocyclic amines with phenylboronic acid using CuFAP catalyst at room temperature, and the results are listed in Table 33. All the reactions proceeded very efficiently at room temperature and yielded the corresponding N-arylated products. It was interesting to note that the formation of the conceivable diarylated product is not observed in our conditions. 

Comparable results were obtained for asymmetric conjugate addition of aromatic and aliphatic thiols to chalcones [88], For this reaction it was also observed that 31 was a more suitable catalyst than derivatives with, for example, a 4-CH3OC6H4, a 3,5-(CH3)2C6H3, or a cyclohexyl group, which is in line with the expectation that the acidity of the squaramide N-H groups is related to the stereoselectivity and yield of the catalytic reaction. 

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