Corynebacterium parvum

Analysis by SDS-polyacrylamide gel electrophoresis of purified NOS from isolated HC from rats injected with killed Corynebacterium parvum (H), and from the murine macrophage cell line RAW 264-7 (M) (courtesy of D. Stuehr, The Cleveland Clinic, Cleveland, OH) which was exposed to LPS and IFNy. Crude cytosols were separated using ion exchange and affinity 2 5 -ADP Sepharose chromatography. Last step by gel filtration is equivalent to separation by molecular weight. [Pg.226]

The 48-h concanavalin A-induced lymphoblastogenic responses in splenocytes isolated from BALB/c mice treated with Corynebacterium parvum and 1,1-dimethylhydrazine mice were significantly increased in comparison with C. parvum treatment alone (Frazier et al., 1992), indicating that 1,1-dimethylhydrazine can overcome certain types of immunosuppression. [Pg.1428]

BCG is a viable strain of Mycobacterium bovis that has been used for immunization against tuberculosis. It has also been employed as a nonspecific adjuvant or immunostimulant in cancer therapy but has been successful only in intravesical therapy for superficial bladder cancer. BCG appears to act at least in part via activation of macrophages to make them more effective killer cells in concert with lymphoid cells in the cellular efferent limb of the immune response. Lipid extracts of BCG as well as nonviable preparations of Corynebacterium parvum may have similar nonspecific immunostimulant properties. A chemically defined derivative of the BCG cell wall, [Lys18]-muramyl dipeptide, has been licensed in Japan to enhance bone marrow recovery after cancer chemotherapy. [Pg.1355]

Li XY, Lamb D, Donaldson K. 1994. Mesothelial cell injury caused by pleural leukocytes from rats treated with intratracheal instillation of crocidolite asbestos or Corynebacterium parvum. Environ Res 64(2) 181-191. [Pg.294]

Inactivated Corynebacterium parvum has been tried as an adjuvant in patients with cancer and in the treatment of malignant pleural effusions. Fever and chiUs were frequent, with sustained fever and chest or abdominal pain in several patients (1,2). [Pg.983]

Ludwig Lung Cancer Study Group. Adverse effect of intrapleural Corynebacterium parvum as adjuvant therapy in resected stage I and II non-small cell carcinoma of the lung. J Thorac Cardiovasc Surg 1985 89(6) 842-7. [Pg.983]

Forest V. Intrapleural Corynebacterium parvum for recurrent malignant pleural effusions. Respiration 1995 62(l) 21-6. [Pg.983]

Polysaccharides may be active components in undefined aqueous extracts (from sonicated E. coli) which inhibited ascites tumors, such as Sarcoma 180, Ehrlich carcinoma, and MM2 in ddD mice.70 Likewise, polysaccharides may be implicated in the activity of heat-killed Corynebacterium parvum against tumors in mice.71-73... [Pg.243]

Senaldi G, Shaklee CL, Mak TW, Ulich TR. Corynebacterium parvum- and Mycobacterium bovis Bacillus Calmette and Guerin-induced granuloma formation in mice lacking CD4 and CDS. Cell Immunol 1999 193 155-161. [Pg.341]

III. Effects of NO Synthesis Induced by Endotoxin or Corynebacterium parvum on Total CYP Heme and Total Microsomal Heme------------------------------... [Pg.279]

TABLE II Effects of Endogenous Nitric Oxide Synthesis on Total Cytochrome M50 Heme and Total Microsomal Heme in Microsomes from Freshly Isolated and Cultured Hepatocytes of Corynebacterium parvum-Treated Rats ... [Pg.281]

Raiford, D. S., and Thigpen, M. C. (1994). Kupffer cell stimulation with Corynebacterium parvum reduces some cytochrome P450-dependent activities and diminishes acetaminophen and carbon tetrachloride-induced liver injury in the rat. Toxicol. Appl. Pharmacol. 129, 36-45. [Pg.290]

A -THC, WIN55212-2, HU210 3.125-50 mg/kg Mouse, control or primed with Corynebacterium parvum Circnlating levels of TNF-a, IL-12, IL-10... [Pg.437]

Bacterial species such as Bacille Calmette-Gu" rin, Bordetellapertussis, or Corynebacterium parvum. [Pg.405]

Lau BHS, Woolley JL, Marsh CL, Barker GR, Koobs DH, Torrey RR (1986) Superiority of intralesional immunotherapy with corynebacterium parvum and allium sativum in control of murine transitional cell carcinoma. J Urol 136 701-705... [Pg.287]

Adlam C, Broughton E and Scott MT (1972) Enhanced resistance of mice to infection with bacteria following pre-treatment with Corynebacterium parvum. Nature New Biol 235 219-224... [Pg.249]

Baum M and Breese M (1976) Antitumour effect of Corynebacterium parvum. Possible mode of action. Br J Cancer 33 468-473... [Pg.251]

Bomford R and Olivotto M (1975) Inhibition by Corynebacterium parvum of lung-nodule formation by intravenously injected fibrosarcoma cells. In Halpem B (ed) Corynebacterium parvum. Applications in Experimental and Clinical Oncology, pp 268-275. Plenum Press, New York... [Pg.252]

Cerutti I (1975) Antiviral properties of Corynebacterium parvum. In Halpem B (ed)... [Pg.253]

Corynebacterium parvum. Applications in Experimental and Clinical Oncology, pp 84-90. Plenum Press, New York... [Pg.253]

Fauve RM (1975) Stimulating effect of Corynebacterium parvum and C. parvum extract on the macrophage activities against Salmonella typhimurium and Listeria monocytogenes. [Pg.257]

See also in sourсe #XX -- [ Pg.132 , Pg.140 , Pg.141 ]

See also in sourсe #XX -- [ Pg.390 ]

See also in sourсe #XX -- [ Pg.218 ]

See also in sourсe #XX -- [ Pg.4 , Pg.13 , Pg.23 , Pg.134 ]

See also in sourсe #XX -- [ Pg.134 ]

See also in sourсe #XX -- [ Pg.103 ]

See also in sourсe #XX -- [ Pg.735 ]

See also in sourсe #XX -- [ Pg.2 , Pg.32 , Pg.33 , Pg.238 , Pg.239 , Pg.240 , Pg.241 ]

See also in sourсe #XX -- [ Pg.22 ]

See also in sourсe #XX -- [ Pg.138 ]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...