Cleaning inspection procedures

According to Section 1910.134(b) of the Occupational Safety and Health Standards in Title 29 of the U.S. Code of Federal Regulations, an acceptable respiratory program must be instigated whenever respiratory health hazards are present in the work environment. The employer must develop formal written operational procedures covering every aspect of the program, including, for example, how contaminants are controlled, how contaminant concentration is measured, and how respirators are selected, used, cleaned, inspected, repaired, and stored. 

All pipelines and other equipment for transporting product to the packaging line should be thoroughly cleaned, inspected and labelled according to a specific written procedure. 

Studies involving bile salts in EKC separations include (i) determination of i -triazines and quats in well water samples (ii) separation of the 16 priority pollutant PAHs for inspection in ambient air samples (iii) characterization of the electrophoretic behavior of 56 aromatic compounds (phenoxy acid herbicides, phenylalkanoic acids, aromatic carboxylic acids, aromatic sulfonic acids, azo and other dyes, and nitrogen-containing aromatic acids) for further assessment of extraction and sample clean-up procedures using spiked water and soils and (iv) recovery of synthetic dyes from spiked water and soil matrices. Another interesting application of MEKC with diverse bile salts is the prediction of ecotoxicity of aromatic compounds. ... 

These procedures should include all necessary flushing, cleaning, inspections, and tests before introduction of chemicals, resins, or packing. They should consider and detail how chemicals will be introduced into the process and the subsequent operations required to bring the system up to operational capability. Careful consideration should be given as to how all control loops will be set up and tuned, on-line process and analytical instrumentation tested and calibrated, and alarm trips and interlocks verified. 

A particularly insidious failure mechanism that is commonly found in carbon-steel tubing is under-deposit corrosion. In many cases, corrosion products fomi a scab that can mask the presence of the pitting, making it difficult to quantitatively assess using conventional NDT methods. However, by combining proper cleaning procedures with laser-based inspection methods, the internal surface of the tubing can be accurately characterized and the presence of under-deposit corrosion can be confirmed and quantified. 

Clean and inspect equipment after each change Segregate incompatible materials Label material, lines, pumps and valves Use double check system Check labels against batch sheets Use procedures and training Set valves to correct flow path... 

Segregate incompatible materials Clean and inspect equipment after each batch Use procedures and training... 

Before carrying out any inspections or maintenance procedures on belt drives, make sure they are not in operation. Equipment operators should electrically isolate the drive system and lock-out and tag the machine that is to undergo maintenance. Once this precaution has been taken, the belts and pulleys can be removed from the machine for inspection, cleaning, and repair. 

Where an idle boiler is also subject to cleaning and inspection before going back online, these procedures usually are carried out at the end of the idle period to avoid the risk of corrosion to a clean boiler. 

To satisfy government agencies, instruments need to be adequately tested, calibrated, and/or standardized according to documented procedures. Current GLP standards state that equipment used in the generation, measurement, or assessment of data and equipment used for facility environmental control must be of appropriate design and capacity to function according to the protocol and shall be suitably located for operation, inspection, cleaning, and maintenance. 

Defined maintenance procedures should include model or manufacturer specifics and a list of parts to be inspected, cleaned, lubricated, replaced, and/or calibrated. The replacement part numbers, cleaning solutions and lubricants, and calibration standards, along with the manufacturer s maintenance procedures to be followed, should be specified. Documentation is easily managed by creating a one-page checklist of instructions or performance parameters that can be checked off as each task is completed. Any issues or comments can be captured directly on the checklist. Provisions for failure or out-of-tolerance notification need to be clearly defined, as the equipment cannot be put back into service until the performance has been verified by conducting a performance qualification. 

These procedures may also include pre-use inspection steps, clean-up after use, and periodic preventive maintenance that is appropriately performed by users of the equipment. 

Laboratory apparatus should be periodically inspected, cleaned, maintained, and calibrated according to standard operating procedures. 

The purpose is to validate the cleaning procedure and ensure that residues of previous product are removed in accordance with the maximum allowable carryover limit calculated, as well as other tests, i.e., visual inspection, pH, conductivity, and TOC. 

The written Standard Operating Procedures required under 58.81(b)(ll) shall set forth in sufficient detail the methods, materials, and schedules to be used in the routine inspection, cleaning, maintenance, testing, calibration, and/or standardization of equipment, and shall specify, when appropriate, remedial action to be taken in the event of failure or malfunction of equipment. The written standard operating procedures shall designate the person responsible for the performance of each operation. 

Screening of ENRO, CIPRO, DAN, NOR, FLU, OXO, and NALA in pork muscle was based on HPTLC after the SPE procedure (195). Tissue samples were extracted with MeCN-NaOH, the supernatant dried, and the residues dissolved in dipotassium hydrogen phosphate buffer (pH 7.4) hexane was added. The aqueous phase was cleaned up using the SPE technique. After washing the cartridge, analytes were eluted with MeOH-ammonia solution (75 25). After the preparation step, extracts were spotted and eluted on silica gel plates. The plate is first inspected under UV illumination at 312 nm and then sprayed with terbium chloride. The method was validated at the levels of 15 yug/kg for ENRO, CPRO, DAN, and NOR and 5 yug/kg for FLU, 0X0, and NALA. 

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