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Channel Architecture

Channel-forming proteins exhibit a number of structural motifs the influenza virus M2 proton channel and voltage-gated channels for K+, Na+ and Ca2+are all composed of four identical subunits that aggregate to form a central pore as shown in Fig. 5.7 an acid sensing Na+ ion channel has a similar structure but with threefold symmetry Ca2+ release channels, the divalent metal ion transporter CorA, the [Pg.161]


A quantitative data analysis of the fluorescence intensity in the 10 detection lanes revealed strong intensity in five lanes, one weak signal in one lane and four lanes without any detectable fluorescence, which is in line with a bi-laminated pattern fed to a multi-channel architecture [162]. [Pg.243]

Several channel architectures have been considered when designing artificial mimics. The most obvious biologically inspired method is to prepare extended helical molecules in an attempt to reproduce the channels either within the helix or where the molecules meet. A small number of systems have been designed using this... [Pg.172]

Tsai SC, Lu H, Cane DE, Khosla C, Stroud RM. Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases. Biochemistry 2002 41 12598-12606. [Pg.1534]

IBM -compatible computer Originally, any personal computer compatible with the IBM line of personal computers. With the launch of IBM s proprietary micro channel architecture in the PS/2 line of computers, which replaced the AT bus, two incompatible standards emerged, and so the term became misleading. Now, it is becoming more common to use the term industry-standard computer when referring to a computer that uses the AT or ISA bus, and the term DOS computer to describe any PC that runs DOS and is based on one of the Intel family of chips. [Pg.838]

IBM PS/2 A series of personal computers using several different Intel processors, introduced by IBM in 1987. The main difference between the PS/2 line and earlier IBM personal computers was a major change to the internal bus. Previous computers used the AT bus, also known as industry-standard architecture, but IBM used the proprietary micro channel architecture in the PS/2 line instead. Micro channel architecture expansion boards will not work in a computer using ISA. See IBM-compatible computer. [Pg.839]

XGA Acronym for Extended Graphics Array. XGA is only available as a micro channel architecture expansion board it is not available in ISA or EISA form. XGA supports resolution of 1024 horizontal pixels by 768 vertical pixels with 256 colors, as well as a VGA mode of 640 pixels by 480 pixels with 65,536 colors, and like the 8514/A, XGA is interlaced. XGA is optimized for use with graphical user interfaces, and instead of being very good at drawing lines, it is a bit-block transfer device designed to move blocks of bits Hke windows or dialog boxes. [Pg.871]

C. The Micro Channel Architecture (MCA) bus was developed by IBM for their PS/2 computers as an upgrade to the ISA architecture. See Chapter 5 for more information. [Pg.896]

MOR = 0.015. These results can be directly related to the micro-porous structure of the different catalysts, for which the pores of the tridimensional Y framework allow a readier diffusion of both substrate and product than those of the interconnected channels architecture of BEA and those of the bidimensional MOR framework. [Pg.79]

Describe the subunit structure, ligand binding sites, and channel architecture of the... [Pg.213]

Energetics and Gating of Narrow Ionic Channels The Influence of Channel Architecture and Lipid-Channel Interactions... [Pg.6]

SPINLINE3 architectures are designed using two kinds of basic components Processing Units (PU) and data links. Theses basic components are combined to implement multi channel architectures with distribution of treatments and redundancy of data links where relevant in order to meet the functional and non-functional requirements. The properties of the processing units and data links ensure a deterministic system behavior with bounded response time for the functions under any load conditions. [Pg.38]

Microporous carriers as zeolites and molecular sieves are preferred catalyst carriers, because of the large variety of micrporous structures which are available and because of the regular pore or channel architecture of each of those materials. [Pg.559]

In the last years, the separation method of field-flow fractionation (FFF) comes more into the focus of size determination and separation of polymer mixtures consisting of different components, for example, aggregates, gels, or defined assemblies. Here, the separation takes place in a long and narrow chaimel, where a carrier liquid transports the molecules. Perpendicular to the main flow direction, a force field will be applied, which influences the sample molecules in order to separate thena. Caused by the channel architecture, the... [Pg.142]

The selectivity of the sodium channels in excitable membranes may well depend on the ability of the ion to interact with fixed anionic or hydrogen bonding sites, together with the requirement to lose some or all of the water from the co-ordination sphere. The free energy of solvation and interaction with anionic sites will increase with ionic radius, but other subtleties of channel architecture may play important roles. [Pg.22]

Generic failure rates were chosen from the Safety Equipment Reliability Handbook (Ref. 4) and referenced. For the PLC, a "Generic S1L2" safety PLC was chosen with a single channel architecture. [Pg.197]

NOTE Whether or not the potential Is realized may depend on the channel architecture of the system in systems with multiple channels to Improve safety, a dangerous hardware failure is less likely to lead to the overall hazardous or fail-to-function state. [Pg.26]

NOTE 1 Whether or not the potential is realized may depend on the channel architecture cf the system. [Pg.34]

The proposed requirements have been further elaborated and now comprise the concept of White and Black Channel architectures. Briefly ... [Pg.288]

This contract implies that there is never a situation in which a wrong output is present in the absence of the safe-state. This timing behaviour might be correct for safety concepts using multi-channel architectures and voting, but it is not correct in case malfunctions are detected by periodic tests. Therefore the perm operator has been introduced, leading to an additional contract template C3... [Pg.100]


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