Microcrystalline cellulose

Both inorganic and organic sorbent materials are suitable for apphcation in partition PLC. The relevant material in this connection is cellulose. Celluloses are natural products with the universal chemical formula (CgHioOj),. These native celluloses have a fibrous structure and they need to be groimd and purified before use in PLC. Besides native cellulose, microcrystalline cellulose can also be used in partition PLC. In this case the cellulose has been recrystaUized and is rod-shaped. The specific surface area of celluloses is in the range of about 2 m /g. [Pg.55]

The total cellulose (microcrystalline cellulose and carboxymethylcellulose sodium) quantitation is achievable through use of one of the following (1) total solid subtraction, (2) indirect quantification of sodium carboxymethylcellulose (NaCMC), or (3) direct quantification of the hydrolyzed monosaccharide. [Pg.90]

Methyl Ethyl Cellulose Microcrystalline Wax Paraffin, Synthetic Petroleum Wax Petroleum Wax, Synthetic Poloxamer... [Pg.130]

Anticaking agents commonly used include calcium carbonate, phosphate, silicate, and stearate cellulose (microcrystalline) kaolin magnesium carbonate, hydroxide, oxide, silicate, and stearate myristates palmitates phosphates silica (silicon dioxide) sodium ferrocyanide sodium silicoa-lummale and starches. [Pg.132]

Microcrystalline Cellulose. Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. It is widely used in pharmaceutical dosage forms, primarily as a filler-binder in oral tablets and capsules with both wet granulation and direct compression processes. Microcrystalline cellulose was marketed first in 1964 by the FMC Corporation under name Avicel PH in four different particle size grades, each with different properties.37 Addition of Avicel into a spray-dried lactose-based formulation overcame compressibility problems. At the same time, the lactose enhanced the flowability of the Avicel products available at that time. The direct compression tableting process became a reality, rather than a concept, partially because of the availability of Avicel. As of 2007, Avicel PH is commercially available in 10 types with different particle size, density, and moisture grades that have different properties and applications (Table 7.6).38 Other brands of microcrystalline cellulose are also available on the pharmaceutical market, including Pharmacel 101 and 102 from DMV International and Emcocel 50 M and 90 M from JRS Pharma. [Pg.175]

Another form of cellulose, microcrystalline cellulose, has been used for pharmaceutical applications. Microcrystalline cellulose is a nonhbrous form of cellulose in which the cellulose fibers are fragmented into particle forms ranging in size from... [Pg.488]

Cellulose, Microcrystalline, 95 Cellulose, Modified, (SI) 14 Cellulose, Powdered, 96 Centrifuge, Defined, 4 Ceric Ammonium Nitrate TS, 851 Ceric Sulfate, 0.01 N, 856 Ceric Sulfate, 0.1 N, 856 Chamomile Oil, English Type, 98, 578 Chamomile Oil, German Type, 98, 578 Chamomile Oil, Hungarian Type, 98 Changes in Format to the Food Chemicals Codex, Fourth Edition, xv Chemical Formulas and Atomic Weights, 3... [Pg.121]

Powder Leuprolide, calcitonin, FITC-dextran Hydroxypropyl cellulose, microcrystalline cellulose In rabbits Enhanced absorption 49... [Pg.673]

Abbreviations CMM, cellulose microcrystalline PEG, polyethylene glycal CMCNa, sodium carboxymethyl cellulose PVP, Kollidon K30 SDS, sodium docecyl sulfate MgEs, magnesium stearate NF, no flow ability. [Pg.1000]

SEPIFILM 003 and 752 The association of cellulose with a film coating agent was originally patented by SEPPIC. Microcrystalline cellulose is probably one of the most extensively used excipients in pharmaceutical and nutritional products. Unlike other fillers, such as lactose, cellulose is inert, vegetable derived, and accepted worldwide and its shelf life is unlimited. Figure 31 shows the advantage of cellulose microcrystalline in film coating. [Pg.1024]

Cores of 300mg that contained 50% ranitidine HC1, cellulose microcrystalline (PH-102) 27.25%,pregelatinized starch 22%, Aerosil 0.5%, and magnesium stearate... [Pg.1027]

MN 300 or 400 Machery Nagel proprietary fibrous celluloses Avicel American Viscose cellulose (microcrystalline)... [Pg.63]

CELLULOSE GUM see SF0500 CELLULOSE METHYL see MIF760 CELLULOSE METHYLATE see MIF760 CELLULOSE, MICROCRYSTALLINE see CCUlOO CELLULOSE NITRATE see CCU250 CELLULOSE, NITRATE (9CI) see CCU250 CELLULOSE, POWDERED see CCU150... [Pg.1567]

Cellulose, microcrystalline Good compression properties, may not need lubricant, can act as disintegrant (Avicel , Emcocel , Vivacel )... [Pg.3656]

Cellulose, microcrystalline silicified Combination of microcrystalline cellulose and silica (Prosolv )... [Pg.3656]

Cellulose, microcrystalline Avicel , Emcocel , Vivacel Highly compressible, low bulk density, acts as disintegrant... [Pg.3664]

Kothari SH, Kumar V, Banker GS. Comparative evaluations of powder and mechanical properties of low crystallinity celluloses, microcrystalline celluloses, and powdered celluloses. Int J Pharm 2002 232 69-80. [Pg.135]

Silicified microcrystalline cellulose is a synergistic, intimate physical mixture of two components microcrystalline cellulose and colloidal silicon dioxide (for further information see Cellulose, Microcrystalline and Colloidal Silicon Dioxide). Silicified microcrystalline cellulose contains 2% w/w colloidal silicon dioxide. [Pg.139]

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