CDS T cell

Cavani, A., et al., Characterization of epitopes recognized by hapten-specific CD-4+ T cells. Journal of Immunology, 154, 1232, 1995. 

Pasare, C. and Medzhitov, R. 2004. Toll-dependent control mechanisms of CD 4 T cell activation. Immunity 21 733-741. 

Delaney C. Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CDS 4-T-cell response against the nonengrafted unit. Blood 2010 115(4) 757-65. 

Fig. 4. Cell interactions, cell surface determinants and cytokines in the ACAID pathway to CDS suppressor T cells. 

CD 4 T-helper cells Zytomed Berlin Medak Wedel... 

CDS Defines MHC class I-restricted T cell subset present on NK cells CDIO Known to be common acute leukaemia antigen CDlla Known to be zn a chain of LFA-1 (leucocyte function antigen-1) present on several types of leucocyte and which mediates adhesion CDllc Known to be z complement receptor 4 a chain. 

CD8 + T cells are driven by MHC class I molecules and do not require professional APC. CD 45 Ro + CD8 + T cells are increased in early infection and are often maintained in symptomatic disease however, dendritic cells are important in stimulating cytotoxic T lymphocyte (CTL) responses in unprimed CD8 + T cell. CD8 cells may also be subdivided based on their cytokine secretion. CD8 CTL clones produce INF-y, IL-6, TNF-a, and ILIO, whereas suppressor cells produce high levels of cytokines associated with Th-2 cells, including IL-4 and low levels of IL-5, IL-6, and IL-10. 

Blair PJ, BultmanSJ, Haas JC, Rouse BT, Wilkinson JE, Godfrey VL CD4 4- CDS — T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. 

Karwot R, Maxeiner JH, Schmitt S, et al Protective role of nuclear factor of activated T cells 2 in CDS 4- long-lived memory T cells in an allergy 33... 

Seymour BW. Gershwin LJ. Coffman RL Aerosol-induced immunoglobulin-E unresponsiveness to ovalbumin does not require CDS 4- or T-cell receptor-y/8-H T cells or interferon-y in a murine model of allergen sensitization. 1 Exp Med 1998 187 721-731. 

A relatively recent twist in studying SE toxicity has employed transgenic mice. As an example, animals expressing both human HEA-DQ6 and duster of differentiation antigen (CD)4-positive T cells readily succumb to normally sublethal amounts of SEB (versus nontransgenic controls) without any potentiating... 

Fig. 1. Photomicrographs of a reactive lymph node follicle with germinal center (G), mantle (M), and surrounding paracortex (P) immunostained using the avi-din-biotin complex technique. (Top) Follicle stained with an antibody specific to B-cells, B1 (CD20) (Coulter Immunology, Hialeah, FL), counterstained with Methyl Green. (Bottom) Parallel section of the same follicle stained with an antibody specific to T-cells, Leu 4 (CDS) (Becton-Dickinson, Mountain View, CA). Scale bar = 100 p.

Kilmartin et al. (2006) 7 CD subjects Immune response of gliadin-reactive mucosal T cell lines to wheat, barley, rye, and oat-related cereals All 5 T cell lines demonstrated immunoreactivity to protein fractions from 4 related cereals Some cell lines reactivity to wheat, barley, and rye was evident only when cereal fractions were pretreated with tTG Confirms similar T cell antigenic reactivity of 4 related cereals... 

Beyer M, Schultze JL. 2007. CD 4+CD25+high Foxp3+ regulatory T cells in peripheral blood are primarily of effector memory phenotype. J Clin Oncol. 25 2628-2630. 

Hong J, Zang YC, Nie H, Zhong J. 2006. CD 4+ regulatory T cell responses induced by T cell vaccination in patients with multiple sclerosis, PNAS. 103 5024-5029. 

Shevach EM. 2002. CD 4+CD25+ suppressor T cells More questions than answers. Nat Rev Immunol. 2 389 100. 

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