Diseases pathogenesis

Major advances made in our understanding of the immune system and disease pathogenesis have... 

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In addition to CIA, there are several other models of arthritis that have also provided evidence for an important role of the chemokine system. Next, we will review some of the data available regarding the contribution of chemokines to disease pathogenesis in specific model systems beyond mere description of any given factor in the joints. 

It seems obvious to assume that by virtue of their powerful regulatory effects of leukocyte recruitment, many chemokine/chemokine receptors may play an important role in an inflammatory disease of the joints such as RA. However, chemokines may have other effects in disease pathogenesis that may not be related to leukocyte chemotaxis. 

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Gene Protein Location Inheritance Relevance to Alzheimer s disease pathogenesis... 

Blair PJ, BultmanSJ, Haas JC, Rouse BT, Wilkinson JE, Godfrey VL CD4 4- CDS — T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. 

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Parihar MS, Hemnani T. Alzheimer s disease pathogenesis and therapeutic interventions. / Clin Neurosci 2004 11 456-67. 

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