Biosensors gold nanoparticles-based

The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticles and nanotubes nanomaterial-based electrochemical DNA detection electrochemical detection of microorganism-based DNA biosensor gold nanoparticle-based electrochemical DNA biosensors electrochemical detection of the aptamer-target interaction nanoparticle-induced catalysis for DNA biosensing basic terms regarding electrochemical DNA (nucleic acids) biosensors screen-printed electrodes for electrochemical DNA detection application of field-effect transistors to label-free electrical DNA biosensor arrays and electrochemical detection of nucleic acids using branched DNA amplifiers. 

Pingarron, J.M., P. Yanez-Sedeno, and A. Gonzalez-Cortes. 2008. Gold nanoparticle-based electrochemical biosensors. Electrochim. Acta 53 5848-5866. 

The other fundamental advantage of gold nanoparticles-based electrochemical DNA biosensors is the development of amplification routes for the DNA sensing events. According to Willner etal. [7], the concept of the amplified detection of DNA using gold nanoparticles... 

Table 4.1. Gold nanoparticle-based electrochemical DNA biosensors using direct detection of redox markers...

Table 4.6. Gold nanoparticle-based electrochemical biosensors using signal enhancement methods... 

Ou,L. J., JinJ. Y.,etal. Sensitiveand Visual Detection of Sequence-Specific DNA-Bind-ing Protein via a Gold Nanoparticle-Based Colorimetric Biosensor. "Analytical Chemis-hy,82(14), 6015-6024 (2010). 

Shang, L., Yin, J.,et al. Gold nanoparticle-based near-inlrared fluorescent detection of biological thiols in human plasma. Biosensors and Bioelectronics,25(2), 269-274 (2009). 

Yaftez-Sedeno, P. and Pingarrbn, J. M. Gold nanoparticle-based electrochemical biosensors. Analytical and Bioanalytical Chemistry,382(4), 884-886 (2005). 

Gold Nanoparticles-Based Optically Detectable Biosensors.171... 

Pingarron JM, Yanez-Sedeno P, Gonzalez-Cortes A. Gold nanoparticle-based electrochemical biosensors. Electrochimica Acta 2008 53 5848-66. http //dx.doi.0rg/lO.lOl6/j.electacta. 2008.03.005. 

Particularly attractive for numerous bioanalytical applications are colloidal metal (e.g., gold) and semiconductor quantum dot nanoparticles. The conductivity and catalytic properties of such systems have been employed for developing electrochemical gas sensors, electrochemical sensors based on molecular- or polymer-functionalized nanoparticle sensing interfaces, and for the construction of different biosensors including enzyme-based electrodes, immunosensors, and DNA sensors. Advances in the application of molecular and biomolecular functionalized metal, semiconductor, and magnetic particles for electroanalytical and bio-electroanalytical applications have been reviewed by Katz et al. [142]. 

Zhong X, Yuan R, Chai Y, Liu Y, Dai J, Tang D (2005) Glucose biosensor based on self-assembled gold nanoparticles and double-layer 2d-network (3-mercaptopropyl)-trimethoxy-silane polymer onto gold substrate. Sensor Actuator B 104 191-198... 

V. Carralero Sanz, M.L. Mena, A. Gonzalez-Cortes, P. Yanez-Sedeno and J.M. Pingarron, Development of a tyrosinase biosensor based on gold nanoparticles-modified glassy carbon electrodes. Application to the measurement of a bioelectrochemical polyphenols index in wines, Anal. Chim. Acta, 528(1) (2005) 1-8. 

Recently, a renewable potentiometric urease inhibition biosensor based on self-assembled gold nanoparticles has been developed by Yunhui et al. for the determination of mercury ions [43]. The advantages of self-assembled immobilization are low detection limit (0.05 iM), fast response, and relatively easy regeneration of the biosensors. The assembled gold nanoparticles and inactivated enzyme layers denatured by Hg2+ can be rinsed out via a saline solution with acid and alkali successively. 

Y. Yang, Z. Wang, M. Yang, M. Guo, Z. Wu, G. Shen and R. Yu, Inhibitive determination of mercury ion using a renewable urease biosensor based on self-assembled gold nanoparticles, Sens. Actuators B, 114 (2006) 1-8. 

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