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Arteriosclerosis and heart disease

Ahrens, E. H Jr. 1982. Diet and heart disease Shaping public perceptions when proof is lacking. Arteriosclerosis 2, 85-86. [Pg.391]

Indications Liver/kidney yin deficiency, liver yang ascendancy, qi and blood counterflow and chaos. Wind stroke, convulsions, epilepsy, cerebrovascular accident, aphasia, apraxia, renal hypertension, essential hypertension, hypertensive encephalopathy, cerebral arteriosclerosis, arteriosclerotic heart disease, hyperthyroidism, premenstrual tension, postpartum fever with spasms and convulsions, and glaucoma... [Pg.171]

Christie (2) has discussed various functions of lipids as follows their involvement in disturbances of lipid metabolism associated with specific lipidoses and gangliosidoses accumulation of various neutral, complex, and conjugated lipids in arteriosclerosis and atherosclerosis (coronary blood vessel and heart disease) the role of lipids in nutrition, disease, and human welfare the importance of fats and oils as agricultural products and as major items in international trade the role of fats as a major dietary component and supplier of calories for humans in developed countries the contribution that fats make to the taste and structure of foods. [Pg.688]

Heart disease is any condition that diminishes the hearts ability to pump blood. A common heart disease is arteriosclerosis, a buildup of plaque on the inside walls of arteries. As discussed in Section 13.8, plaque deposits are mostly an accumulation of low-density lipoproteins, which are high in cholesterol and saturated fats. Plaque-filled arteries are less elastic and have a decreased volume. Both these effects make pumping blood more difficult, and the heart becomes overworked and weakens. Accumulated damage to heart muscle from arteriosclerosis or other stresses can result in abnormal heart rhythms, known as arrhythmia. Chest pains, known as angina, result from an insufficient oxygen supply to heart muscles. Ultimately, the weakened heart does not adequately circulate blood to the body. People with heart disease have decreased stamina and frequently need to catch their breath. [Pg.511]

The determination of cholesterol is important for the diagnosis and prevention of a number of clinical disorders such as hypertension, arteriosclerosis, cerebral thrombosis and coronary heart disease. As the majority of cholesterol in human blood is present in an esterified form, a separate saponification step is required to obtain a total cholesterol analysis early methods for this involved caustic and toxic reagents, long analysis times and a relatively large sample volume. Free cholesterol can be determined chromatographically, although this requires cumbersome and expensive laboratory-based equipment. Modern methods use the enzyme cholesterol esterase to release esterified cholesterol which is then oxidised by a second enzyme, cholesterol oxidase (ChOx, Fig. 23.3) [48]. [Pg.504]

Chen, C.-J., Chiou, H.-Y., Chiang, M.-H. et al. (1996) Dose-response relationship between ischemic heart disease mortality and long-term arsenic exposure. Arteriosclerosis, Thrombosis, and Vascular Biology, 16(4), 504-10. [Pg.266]

Cardiovascular Disease. Patients with systemic hypertension, arteriosclerosis, and other cardiovascular diseases may be at risk when high concentrations of topically administered adrenergic agonists such as phenylephrine are used. Repeated topical doses or soaked cotton pledgets placed in the conjunctival sac have been associated with adverse cardiovascular effects. Likewise, P-blockers should be avoided or used cautiously in patients with congestive heart disease, severe bradycardia, and high-grade atrioventricular block. Topical P-blockers, however, may be used safely in patients with cardiac pacemakers. [Pg.6]

The food we eat plays a critical role in our overall health. It is believed that a substantial amount of chronic disease risk is diet-related and could be significantly reduced through improvements in dietary habits, e.g., up to 70% of aU cancers in the United States are attributable to diet (95). Indeed, a recent report by the USDA indicates that poor diet and diet-related chronic diseases contribute to five of the ten leading causes of death (heart disease, cancer, stroke, diabetes, and arteriosclerosis) costing the United States economy an estimated 250 billion annually (96). [Pg.623]

For several years, lovastatin represented the commerically most successful drug from nature. Named mevinolin, it was discovered as a metabolite from Aspergillus terreus cultures at the US company Merck by a target-directed screening for inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, a key enzyme of cholesterol biosynthesis [32]. Cholesterol, which in humans more than one-half of the total body cholesterol is derived from its de novo biosynthesis in the liver, is the major component of atherosclerotic plaques built up as fatty deposits on the inner walls of arteries, thus contributing to arteriosclerosis and coronary heart diseases [33]. [Pg.111]

Since Johann Lobstein first coined the term arteriosclerosis, or hardening of the arteries in 1833, to the Framingham Study which began in 1948 (42), to the isolation of mevastatin by Akira Endo in 1976 (43), and on to the publication of the Scandinavian Simvastatin Survival Study (4S) in 1994 (44), cholesterol levels have emerged as perhaps the most potent modifiable risk factor in the treatment of chronic ischemic heart disease. Genetic disorders such as homozygous familial hypercholesterolemia where severe atherosclerosis is present by early adolescence have helped clarify the importance of LDL cholesterol in the pathogenesis of atherosclerosis. [Pg.71]

A year later, in the August/September 2003 issue, Wayne Martin again addresses the prudent diet vs. saturated fats in an article titled The Role of Dietary Polyunsaturated Fats in Heart Disease and Atherosclerosis. (Atherosclerosis is a form of arteriosclerosis.) The data overwhelmingly indicate that saturated fats, whether butter or lard or whatever, are preferable to polyunsaturated fats, contrary to the present conventional wisdom. Moreover, aspirin was found to have no beneficial effect against heart attacks. [Pg.367]

Martin, W. 2003. The Role of Dietary Polyunsaturated Fats in Heart Disease and Arteriosclerosis. Townsend Letterfor Doctors and Patients, nos. 241/242 (August/September) 80-84. [Pg.438]

The nse of methysergide is contraindicated in peripheral vascnlar disease, severe arteriosclerosis, severe hypertension, coronary artery disease, phlebitis or cellnlitis of the lower limbs, pnhnonary disease, collagen disease or fibrotic processes, impaired liver or renal fnnction, and valvnlar heart disease (see also Figure 93). [Pg.435]

Recently, it has been reported that cancer, arteriosclerosis and coronary heart diseases have long been considered major contributors to morbidity and mortality in developed countries. Many medicinal plants and foodstuffs are used for their preventive effects against life-style-related diseases, such as coronary heart diseases, hypertension, thrombosis, allergic inflammation, arteriosclerosis, hyperlipidemia, and cancer. Although based on the classic concept of Diet and Medicine from the Same Source , as described in old Chinese and Japanese medical books, evidence based on clinical and experimental results were not yet clear. I have been using biochemical and pharmacological approaches to study... [Pg.55]

Coronary Heart Disease Several studies have linked mercury exposure to cardiovascular disease. These studies are important because consumers are advised to eat fish to protect against heart disease. Some fish species contain beneficial omega-3 fatty acids, and fish is also a low-fat source of protein. However, recent studies have raised the possibility that a moderate mercury content in fish may diminish the cardioprotective effect of fish intake in humans. Salonen et al. (2000) reported an association between moderate hair mercury content and accelerated progression of carotid arteriosclerosis in a prospective study among 1014 men aged 42-60 years in Finland. Hair mercury levels > 2 pg g showed a doubling of the risk of... [Pg.975]

Th e dm are used cautiously during pregnancy (epinephrine and apraclonidine, Pr nancy Cat ory C dipivefrin, Piregnancy Category B) and lactation and in patients witii hypertension, diabet, hyperthyroidism, heart disease, cerebral arteriosclerosis, or bronchial asthma. Some of these dru contain sulfite that may cause allergic-like reactions (hives, wheezing, anaphylaxis) in patients with sulfite sensitivity. See Chapter 22 for information on interactions. [Pg.627]


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See also in sourсe #XX -- [ Pg.13 ]




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