Early adolescence

The infant, the adult, the aged person, each has is own kind of smell, and... it might be possible, within certain limits, to discover the age of a person by his odor. In both sexes puberty, adolescence, early manhood and womanhood are marked by a gradual development of the adult odor of skin and excreta, in general harmony with the secondary sexual developments of hair and pigment. 

Werry, J.S. (1992) Child and adolescent (early onset) schizophrenia a review in light of DSM-III-R. / Autism Dev Dis 22 601-624. 

Age Mid-teenage years Late adolescence/early adulthood... 

Lee LM, Karon JM, Selik R, Neal JJ, Fleming PL (2001) Survival after AIDS diagnosis in adolescents and adults during the treatment era, United States, 1994-1997. JAMA 285 1308-1315 Li L, Olvera JM, Yoder KE, Mitchell RS, Butler SL, Lieber M, Martin SL, Bushman FD (2001) Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection. EMBO J 20 3272-3281... 

Acne vulgaris typically begins around puberty and early adolescence it tends to present earlier in females, usually at about 12 or 13 years, than in males, 14 or 15 years, due to later onset of puberty in males. Acne has been estimated to affect 95-100% of 16- to 17-year-old boys and 83-85% of 16- to 17-year-old girls. Acne settles in the vast majority by 23-25 years of age, persisting for longer in some 7% of individuals 1% of males and 5% of females exhibit acne lesions at 40 years of age. There is a small group of individuals who develop late-onset acne, beyond the age of 25 years. 

Sampson HA, Mendelson L, Rosen JP Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 1992 327 380-384. De Bilderling G, Mathot M, Agustsson S, Tuerlinckx D. Jamart J. Bodart E Early skin sensitization to aeroallergens. Clin Exp Allergy 2008 38 643-648. 

Epstein-Barr virus (EBV) Enveloped, icosahedral particles 150nm in diameter Infections occur by salivary exchange. In young children they are commonly asymptomatic but the virus persists in a latent form in lymphocytes. Infection delayed until adolescence often results in glandularfever. In tropical Africa, a severe EBV infection early in life predisposes the child to malignant facial tumours (Burkitt s lymphoma)... 

Reductions in aggressive behavior after treatment with amphetamine and other psyehomotor stimulants are seen in children and adolescents who have been diagnosed with hyperkinesis or attention deficit disorder. There is considerable disagreement about these diagnostic categories and about whether the violent outbursts and uncontrolled episodes of aggressive behavior are limited to the early developmental period or continue into adulthood (Mendelson et al. 1971 Minde et al. 1972). 

Personality disorders are inflexible and maladaptive patterns of behavior that deviate markedly from expectations of society. These patterns are stable over time, pervasive and rigid, and lead to distress or impairment in the individual s life. Onset is in adolescence or early adulthood.1 Personality disorders and bipolar disorder may be comorbid, and patients with personality disorders may have mood symptoms. The two diagnoses are distinguished, however, by the predominance of mood symptoms and the episodic course of bipolar disorder, in contrast to the stability and persistence of the behavioral patterns of personality disorders. 

Typically presents in late adolescence or early adulthood. Onset in older adults increases suspicion of relationship to medical disorders or substance use. Laboratory evaluation must be driven by history and physical examination. 

A study of 55 adolescents who had been treated for lead intoxication in early childhood (11-17 years earlier) revealed no evidence of chronic nephropathy, as evidenced by endogenous creatinine clearance, BUN, serum uric acid, and routine urinalysis (Chisolm et al. 1976). PbB levels during the acute poisoning episode ranged from 100 to 650 pg/dL all patients received immediate chelation therapy. At the time of the study, their PbB levels had decreased to less than 40 pg/dL. 

Johnson JG, Cohen P, Pine DS, Klein DF, Kasen S and Brook JS. (2000). Association between cigarette smoking and anxiety disorders during adolescence and early childhood. Journal of the American Medical Association, 284, 2348-2351. 

McGhee R, Williams S, Poulton R and Moffitt T. (2000). A longitudinal study of cannabis use and mental health from adolescence to early adulthood. Addiction, 95, 491-504. 

Wu LT and Anthony JC (1999). Tobacco smoking and depressed mood in late childhood and early adolescence. American Journal of Public Health, 89, 1837-1840. 

Metachromatic leukodystrophy is due to a defect in arylsulfatase A (ASA). There are three major forms late infantile, juvenile and adult. The overall incidence is 1 40,000. In the late infantile and early juvenile forms, which comprise about 80% of patients, the initial symptoms involve the motor system, with falls, loss of ability to walk, flaccid paralysis, difficulty in swallowing, loss of speech, vision, seizures, decerebrate state and death 1-7 years after onset of symptoms. In the adolescent and... 

Schizophrenia is a severe, chronic disabling mental disorder. Schizophrenia affects approximately 1% of the population worldwide. Symptomatic onset occurs in late adolescence and early adulthood in males and somewhat later in females, who tend to be somewhat less severely affected. It is estimated to be the seventh most costly medical illness to society in terms of cost of care and loss of productivity, because less than 30% of affected individuals... 

Golub, M.S., M.E. Gershwin, L.S. Hurley, and A.G. Hendrickx. 1988. Studies of marginal zinc deprivation in rhesus monkeys. VIII. Effects in early adolescence. Amer. Jour. Clin. Nutr. 47 1046-1051. 

The primary goal of osteoporosis management is prevention. Optimizing skeletal development and peak bone mass accrual in childhood, adolescence, and early adulthood will reduce the future incidence of osteoporosis. 

---