Aquatic toxicity potential

Walker, J.D., Knaebel, D., Mayo, K., Tunkel, J. and Gray, D.A. (2004) Use of QSARs to promote more cost-effective use of chemical monitoring resources. 1. Screening industrial chemicals and pesticides, direct food additives, indirect food additives and pharmaceuticals for biodegradation, bioconcentration and aquatic toxicity potential, Water Quality Research Journal of Canada 39, 35-39. 

Aquatic toxicity potential is calculated based on tbe maximum tolerable concentrations of different toxic substances in water by aquatic organisms. 

Score) for aquatic toxicity potential (ATP) for a chemical i were determined by,... 

AP Acidification potential ATP Aquatic toxicity potential APEA Aspen Process Economic Analyzer CEI Chemical exposure index... 

Human Toxicity Potential. As for aquatic toxicity, the database for human toxicity potential is still being established but is based on acceptable daily doses. The total potential is the sum of potentials released to different media. 

For each chemical class, a set of 4-7 key attributes were identified that can be used to differentiate a chemical from others in the same class. These may include biodegradability, aquatic toxicity, sensitization potential, renewable resource derived, and so forth. Each attribute was selected to be ... 

EPA has developed an evaluation tool, the PBT Profiler, which predicts PBT potential of chemicals. The PBT Profiler estimates environmental persistence (P), bioconcentration potential (B), and aquatic toxicity (T) of discrete chemicals based on their molecular structure. It is Internet-based and there is no cost for use. 

The use of screens in environmental assessment and occupational health is fairly straightforward. On the occupational side, the concerns (as addressed in Chapter 11 of this volume) address the potential hazards to those involved in making the bulk drug. The need to address potential environmental concerns covers both true environmental items (aquatic toxicity, etc.) and potential health concerns for environmental exposures of individuals. The resulting work tends to be either regulatorily defined tests (for aquatic toxicity) or defined endpoints such as dermal irritation and sensitization, which have been (in a sense) screened for already in other nonspecific tests. 

While the PEEP index can theoretically be employed to assess the toxic potential of varied liquid media and groups of specific chemical products of interest (Section 8.3), it was originally conceived to appraise that of liquid wastes of point source discharges to aquatic environments. The index is thus described for this purpose in this section. 

The pT-method can be used to assess the toxic potential of both treated and untreated wastewater, surface water (receiving streams), groundwater, pore water, elutriates and chemical extracts of sediments. This paper deals with wastewater, the application of the pT-method to sediments is described in Chapter 9 of this volume. The method can be applied universally and is user-friendly. Any number of aquatic... 

This section illustrates how the SED-TOX index has been effective in assessing the relative toxic potential of freshwater sediments to aquatic organisms. The index was... 

Neely, W.B. (1984) An analysis of aquatic toxicity data Water solubility and acute LC50 fish data. Chemosphere 13, 813-819. Neely, W.B., Branson, D.R. Blau, G.E. (1974) Partition coefficient to measure bioconcentration potential of organic chemicals in fish. Environ. Sci. Technol. 8, 1113-1115. 

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