Anoxia

The mouse anoxia or oxygen-consumption test is based on the stimulation of the basal metaboHc rate by thyromimetic compounds. Mice or other small animals are placed in airtight containers of known volume and their survival time is determined (34). 

ASPHYXIA The result of a diminished supply of oxygen to the blood and tissues and interference with the respiratory function. Simple anoxia may be caused by inert gases , e.g. nitrogen, and some flammable gases, e.g. methane. Toxic anoxia may be caused by certain substances, e.g. carbon monoxide and hydrogen cyanide, which interfere with the body s ability to transfer or utilize oxygen in the tissues. Rapid unconsciousness and death can occur in either case. 

Exert an effect by interference with Simple anoxia caused by oxygen Carbon dioxide methane hydrogen ... 

Toxic anoxia caused by damage to Carbon monoxide cyanogen, hydrogen ... 

Levels below 19.5% oxygen ean have detrimental effeets if the body is already under stress, e.g. at high altitudes. Exposures below 18% should not be permitted under any eireumstanee. Other ehemieals, e.g. earbon monoxide, result in toxie anoxia due to damage of the body s oxygen transport or utilization meehanism. 

Anoxia Anoxia is the absence of oxygen in inspired gases or in arterial blood and/or in the tissues. This is closely related to hypoxia, which is a severe oxygen deficiency in the tissues. One can think of anoxia as the most extreme case of hypoxia. 

Sedbrook, J. C., et al. (1996). Transgenic aequorin reveals organ-specific cytosolic Ca2+ responses to anoxia in Arabidopsis thaliana seedlings. Plant Physiol. Ill 243-257. 

Toxicity. A 1% concn of the gas in air is lethal to rats in 1 hour, its effect being similar to C monoxide the LD50 in rats when injected intra-peritoneally is 8.2ml/kg (Ref 16). Earlier workers assumed that the toxicity of N trifluoride would be similar to H fluoride and that the latter would be formed by hydrolysis in body tissues (Ref 1). This has recently been shown to be erroneous, and that it is stable under physiological conds. The toxic effect is due to its ability to complex with the hemoglobin of the blood causing anoxia. This effect is reversible, and animals receiving a sublethal dose recover rapidly upon removal from contact with N trifluoride (Ref 14)... 

If contractions are frequent, prolonged, or excessive, die infusion is stopped to prevent fetal anoxia or trauma to die uterus. Excessive stimulation of die uterus can cause uterine hypertonicity and possible uterine rupture. The nurse places die patient on her side and provides supplemental oxygen. The effects of die drug diminish rapidly because oxytocin is short acting. 

Perifascicular capillaries are closer to aggregates of antibody-secreting cells (B-lymphocytes) situated in perimysial connective tissue and therefore are most severely affected by antibody-dependent cytotoxic reactions. Immune-complex deposition occurs at a higher level in the vascular tree (i.e., at arteriolar level) and this may cause fluctuations in perfusion pressure. Perifascicular capillaries are most distal from the head of vascular pressure and therefore most likely to suffer from periodic anoxia. 

Continued intracellular freezing Recrystallization Hypoosmolality Indirect effects Tissue anoxia Thrombosis Edema Inflammation... 

Ingall, E. and Jahnke, R. (1997). Influence of water-column anoxia on the elemental fractionation of carbon and phosphorus during sediment diagenesis. Mar. Geol. 139, 219-229. 

Van Cappellen, P. and Ingall, E. D. (1994). Benthic phosphorus regeneration, net primary production, and ocean anoxia A model of the coupled marine biogeochemical cycles of carbon and phosphoms. Paleoceanography 9,677-692. 

Keywords Climate change impacts, Anoxia, Anoxic Factor, ENSO, Streamflow, Sau Reservoir... 

Fig. 11 Schematic representation of cascade effects of climate change on reservoir water quality (expressed as anoxia extent)...

Ntimberg GK (1995) Quantifying anoxia in lakes. Limnol Oceanogr 40 1100-1111... 

After approximately 90 min of anoxia, the induced synthesis of an additional group of c. 20 polypeptides is first detected. This group of 20 anaerobic polypeptides (ANPs) represents more than 70% of the total labelled amino acid incorporation after five hours of anaerobiosis (Fig. 3). By this time the synthesis of the TPs is at a minimal level however, these polypeptides accumulate to a high level during early anaerobiosis and have been shown by pulse-chase experiments to be very stable. The synthesis of... 

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