Trace elements human tissue

Zhong H, Tan M, Eu Y, Huang J and Tang Z (1999) Determination of trace elements in tissue of human uterine cancer by instrumental neutron activation analysis. Biol Trace Elem Res 71-72 569-574. 

An average of about 7 ppm of bromine is found ia terrestrial plants, and edible foods contain up to 20 ppm. Among animals the highest bromide contents are found ia sea life, such as fish, sponges, and cmstaceans (44). Animal tissues contain 1—9 ppm of bromide and blood 5—15 ppm. The World Health Organization has set a maximum acceptable bromide iatake for humans at 1 mg/kg of body weight per day. In adult males the bromine content ia semm has been found to be 3.2—5.6 p.g/mL, ia urine 0.3—7.0 p.g/mL, and ia hair 1.1—49.0 p.g/mL. Bromine may be an essential trace element as are the other hahdes (45). 

We proposed to study diet and health by combining bone chemistry and histomorphometry. Diet would be determined by analysis of stable isotopes of carbon and nitrogen in bone protein and some preserved hair. In addition, trace elements would be quantitatively analyzed in preserved bone mineral. Abonyi (1993) participated in the study by reconstructing the diet from historical sources and analyzing various foods. Having analyzed human tissues for stable isotopes and trace elements, and foods for the same variables, we hoped to learn more about 19th century diet in southern Ontario, and at the same time, learn more about paleodiet reconstruction. 

Radosevich, S.C. (1993). The six deadly sins of trace element analysis A case of wishful thinking in science. In Investigations of Ancient Human Tissue Chemical Analysis in Anthropology, ed. Sandford, M.K., Gordon and Breach, Langhorne, pp. 269-332. 

Tipton IH, Cook MJ. 1963. Trace elements in human tissue. Part II. Adult subjects from the United States. Health Physics 9 103-145. 

Fluoride is a cumulative toxin, which accumulates in mineralized tissues, notably in the lattice of bone and tooth crystals [8,39]. The biological effects in humans due to chronic fluoride ingestion depend not only on the total dosage and duration of exposure, but also on associated factors such as nutritional status, functional status of the renal tissue and interaction with other trace elements [41]. The effect of... 

Analytical issues (i) X-ray elemental microanalysis (ii) Ion-selective electrodes for chnical use. (iii) Electron probe and electron energy loss analysis. (iv) Intracellular measurements . (v) Determination of Mg in human tissues and fluids . (vi) Trace elements in hair. (vii) Determination of Ca and Mg in wines . 

Microdialysis to monitor the chemistry of extracellular space in human tissue is a challenging technique that has been applied in the neurosciences to measure neurochemical composition in vivo.104 Microdialysis coupled online with in-tube solid phase extraction (SPE) and ICP-MS has been developed by Sun et al.105 for the in vivo determination of several trace metals in order to study the transfer kinetics of trace elements in brain extracellular fluid. 

FIGURE 1-12 Elements essential to animal life and health. Bulk elements (shaded orange) are structural components of cells and tissues and are required in the diet in gram quantities daily. For trace elements (shaded bright yellow), the requirements are much smaller for humans, a few milligrams per day of Fe, Cu, and Zn, even less of the others. The elemental requirements for plants and microorganisms are similar to those shown here the ways in which they acquire these elements vary. 

Toulsen et al. (1994) appear to use the term reference interval as synonymous with reference range. In a paper titled Trace element reference values. . . , the authors emphasize that knowledge of the reference intervals (baseline data) for the trace elements in human body fluids and tissues is of paramount importance. ... 

The standard patient has a mass of 70 kg, and the density of the human body is very close to 1 g/mL. What is the body volume of the standard patient in liters Based on this volume and using the data in Table 3.1, determine the molar concentration of iron in the body. Assume all the iron in the body is evenly distributed throughout all tissues. Repeat the calculation on selenium, an element involved in certain oxidation-reduction processes in the body. The lesson of this question is that trace elements can be very trace indeed. 

Stitch SR. 1957. Trace elements in human tissue. I. A semi-quantitative spectrographic survey. Biochem J 67 97-109. 

Sowden EM. 1958. Trace elements in human tissue 3. Strontium and barium in non-skeletal tissue. Biochem J 70 712-715. 

Tipton IH, Schroeder HA, Perry HM, et al. 1965. Trace elements in human tissues Part III. Subjects from Africa, the Near and Far East and Europe. Health Phys 11 403-451. 

VersieckJ. 1985. Trace elements in human body fluids and tissues. CRC Crit Rev Clin Lab Sci 22 97-184. 

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