Tissue engineering mesenchymal stem cells

Jo, J. 1., Nagaya, N., Miyahara, Y, Kataoka, M., Harada-Shiba, M., Kangawa, K., and Tabata, Y. 2007. Transplantation of genetically engineered mesenchymal stem cells improves cardiac function in rats with myocardial infarction Benefit of a novel nonviral vector, cationized dextran. Tissue Engineering, 13,313-322. 

Ob, JS, Ha, Y, An, SS, Kban, M, Pennant, WA, Kim, HJ, Yoon do, H, Lee, M, and Kim, KN. 2010. Hypoxia-preconditioned adipose tissue-derived mesenchymal stem cell increase tbe survival and gene expression of engineered neural stem cells in a spinal cord injury modeL Neuroscience Letters 472(3) 215-219. 

Neuss and coworkers have reported the possibility of SMPs using PCL dimethacrylate copolymers as cellular scaffold for tissue engineering. Behaviors of different cells from three different species (human mesenchymal stem cells, human mesothelial cells, and rat mesothelial cells) on the matrices were investigated, and the differentiation capacity of mesenchymal stem cells on the matrices was also analyzed [329]. The SMPs proved biocompatibility for all tested cell types, supporting viability and proliferation. The SMPs also supported the osteogenic and adipogenic differentiation of human mesenchymal stem cells 3 weeks after induction. 

BC is a good material not only for wound treatment and other fields of veterinary medicine, but also as a scaffold material for cell cultivation in tissue engineering [156,157]. On such scaffolds the fzmb has cultivated the following cell types successfully human osteoblasts, human osteogenic sarcoma cells (SAOS-2), equine osteoblast lines and chondrocytes, and mesenchymal stem cells. 

Meinel, L., Hofmann, S., Karageorgiou, V., Zichner, L., Langer, R., Kaplan, D., and Vunjak-Novakovic, G. "Engineering cartilage-like tissue using human mesenchymal stem cells and silk protein scaffolds". Biotechnol. Bioeng. 88(3), 379-391 (2004a). 

Wise JK et al (2009) Chondrogenic differentiation of human mesenchymal stem cells on oriented nanofibrous scaffolds engineering the superficial zone of articular cartilage. Tissue Eng A 15(4) 913-921... 

Hannouche, D., Terai, H., Fuchs, J. R., Terada, S., Zand, S., Nasseri, B. A., Petite, H., Sedel, L., Vacanti, J. P. Engineering of implantable cartilaginous structures from bone marrow-derived mesenchymal stem cells. Tissue Engineering. 2007,13, 87-99. 

Buxton, A. N., Zhu, J., Marchant, R., West, J. L., Yoo, J. U., Johnstone, B. Design and characterization of poly(ethylene glycol) photopolymerizahle semi-interpenetrating networks for chondrogenesis of human mesenchymal stem cells. Tissue Engineering. 2007,13, 2549-2560. 

Salinas, C. N., Cole, B. B., Kasko, A. M., Anseth, K. S. Chondrogenic differentiation potential of human mesenchymal stem cells photoencapsulated within poly(ethylene glycol)-arginine-glycine-aspartic acid-serine thiol-methacrylate mixed-mode networks. Tissue Engineering. 2007,13, 1025-1034. 

Kim, H., Kim, H. W, Suh, H. Sustained release of ascorbate-2-phosphate and dexamethasone from porous PLGA scaffolds for bone tissue engineering using mesenchymal stem cells. Biomaterials. 2003, 24, 4671-4679. 

Neubauer, M., Hacker, M., Bauer-Kreisel, P., Weiser, B., Fischbach, C., Schulz, M. B., Goepferich, A., Blunk, T. Adipose tissue engineering based on mesenchymal stem cells and basic fibroblast growth factor in vitro. Tissue Engineering. 11,1840-1851. 

Li, W. Tuli, R. Okafor, C. Derfoul, A. Danielson, K.G. Hall, D.J. Tuan, R.S. A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells. Biomaterials 2005, 26 (6), 599-609. 

Shin M, Yoshimoto H, Vacanti JP (2004) In vivo bone tissue engineering using mesenchymal stem cells on a novel electrospun nanofibrous scaffold. Tissue Eng 10 33-41 Shinomiya M, Iwata T, Doi Y (1998) The adsorption of substrate-binding domain of PHB depolymerases to the surface of poly(3-hydroxybutyric acid). Int J Biol Macromol 22 129-135 Sim YC, Sudesh K (Unpublished). Annual report 2009 (2009) http //www.simedaiby.com/ downloads/pdfs/SDB/Annual Report/Sime Darby AR2009.pdf. Accessed online. Accessed Oct 1 2010... 

For specific applications [e.g., bone tissue engineering], BC-gelatin/PA doped with hydroxyapatite [HAp] were synthesized [BC-gelatin/PA/Hap]. The cell compatibility of BC-gelatin/PA/HAp was tested with mesenchymal stem cells [58]. The results indicated that the composite supported cell growth and proliferation, over 7 days of cultivation. Studies on the effectiveness of composites in vitro and in vivo behavior should be further explored. 

K. Ito, Y. Yamada, T. NaiM, M. Ueda, Simultaneous implant placement and bone regeneration around dental implants using tissue-engineered bone with fibrin glue, mesenchymal stem cells and platelet-rich plasma, Clin. Oral Implants Res. 17 (2006) 579-586. 

M.S. Peach, et al., Polyphosphazene functionalized polyester fiber matrices for tendon tissue engineering in vitro evaluation with human mesenchymal stem cells, Biomed. Mater. 7 (4) (2012) 045016. 

S.D. Lin, K.H. Wang, A.P. Kao, Engineered adipose tissue of predefined shape and dimensions from human adipose-derived mesenchymal stem cells. Tissue Eng Part A 14 (2008) 571-581. 

Y.S. Choi, S.N. Park, H. Suh, Adipose tissue engineering using mesenchymal stem cells attached to injectable PLGA spheres. Biomaterials 26 (2005)5855-5863. 

M. Neubauer, et al.. Adipose tissue engineering based on mesenchymal stem cells and basic fibroblast growth factor in vitro. Tissue Eng. 11 (2005)1840-1851. 

A. Alhadlaq, M. Tang, J.J. Mao, Engineered adipose tissue from human mesenchymal stem cells maintains predefined shape and dimension implications in soft tissue augmentation and reconstruction. Tissue Eng. 11 (2005) 556-566. 

J.R. Mauney, et al.. Engineering adipose-Uke tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds, Biomaterials 28 (2007) 5280-5290. 

Meinel, L. Karageorgiou, V. Fajardo, R. Snyder, B. Shinde-Patil, V. Zichner, L. Kaplan, D.L. Langer, R. Vunjak-Novakovic, G. Bone tissue engineering using human mesenchymal stem cells effects of scaffold material and medium flow. Annals Biomed. Eng. 32 112-122 (2004). 

Park, H., Temenoff, J. S., Tabata, Y., Caplan, A. I. Mikos, A. G. (2007) Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials, 28, 3217-27. 

---